PDB entry 2gs6

View 2gs6 on RCSB PDB site
Description: Crystal Structure of the active EGFR kinase domain in complex with an ATP analog-peptide conjugate
Class: transferase
Keywords: EGFR, kinase, active, ATP-analog peptide conjugate, TRANSFERASE
Deposited on 2006-04-25, released 2006-06-20
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-10-18, with a file datestamp of 2017-10-13.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: N/A
AEROSPACI score: 0.19 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Epidermal growth factor receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: EGFR, ERBB1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9H2C9 (3-End)
      • cloning artifact (0-2)
    Domains in SCOPe 2.07: d2gs6a2, d2gs6a3
  • Chain 'B':
    Compound: peptide
    Database cross-references and differences (RAF-indexed):
    • PDB 2GS6
  • Heterogens: CL, 112, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2gs6A (A:)
gamgeapnqallrilketefkkikvlgsgafgtvykglwipegekvkipvaikelreats
pkankeildeayvmasvdnphvcrllgicltstvqlitqlmpfgclldyvrehkdnigsq
yllnwcvqiakgmnyledrrlvhrdlaarnvlvktpqhvkitdfglakllgaeekeyhae
ggkvpikwmalesilhriythqsdvwsygvtvwelmtfgskpydgipaseissilekger
lpqppictidvymimvkcwmidadsrpkfreliiefskmardpqrylviqgdermhlpsp
tdsnfyralmdeedmddvvdadeylipqqg

    Sequence, based on observed residues (ATOM records): (download) 
    >2gs6A (A:)
gamgeapnqallrilketefkkikvlgsgafgtvykglwipegekvkipvaikeltspka
nkeildeayvmasvdnphvcrllgicltstvqlitqlmpfgclldyvrehkdnigsqyll
nwcvqiakgmnyledrrlvhrdlaarnvlvktpqhvkitdfglakllgaeekeyhaeggk
vpikwmalesilhriythqsdvwsygvtvwelmtfgskpydgipaseissilekgerlpq
ppictidvymimvkcwmidadsrpkfreliiefskmardpqrylviqgdermhlpsedmd
dvvdadeylip

  • Chain 'B':
    No sequence available.