PDB entry 2grp

View 2grp on RCSB PDB site
Description: Crystal Structure of human RanGAP1-Ubc9-Y87A
Class: ligase
Keywords: ubiquitin, conjugation, small ubiquitin like modifer, smt3, LIGASE
Deposited on 2006-04-24, released 2006-05-30
The last revision prior to the SCOPe 2.03 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.05 Å
R-factor: 0.191
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ubiquitin-conjugating enzyme E2 I
    Species: Homo sapiens [TaxId:9606]
    Gene: UBE2I, UBC9, UBCE9
    Database cross-references and differences (RAF-indexed):
    • Uniprot P63279 (3-End)
      • engineered (89)
    Domains in SCOPe 2.03: d2grpa_
  • Chain 'B':
    Compound: ran gtpase-activating protein 1
    Species: Homo sapiens [TaxId:9606]
    Gene: RANGAP1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d2grpb_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2grpA (A:)
    gshmsgialsrlaqerkawrkdhpfgfvavptknpdgtmnlmnwecaipgkkgtpweggl
    fklrmlfkddypssppkckfepplfhpnvapsgtvclsileedkdwrpaitikqillgiq
    ellnepniqdpaqaeaytiycqnrveyekrvraqakkfaps
    

    Sequence, based on observed residues (ATOM records): (download)
    >2grpA (A:)
    msgialsrlaqerkawrkdhpfgfvavptknpdgtmnlmnwecaipgkkgtpwegglfkl
    rmlfkddypssppkckfepplfhpnvapsgtvclsileedkdwrpaitikqillgiqell
    nepniqdpaqaeaytiycqnrveyekrvraqakkfap
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >2grpB (B:)
    stgepapvlsspppadvstflafpspekllrlgpkssvliaqqtdtsdpekvvsaflkvs
    svfkdeatvrmavqdavdalmqkafnsssfnsntfltrllvhmgllksedkvkaianlyg
    plmalnhmvqqdyfpkalaplllafvtkpnsalescsfarhsllqtlykv
    

    Sequence, based on observed residues (ATOM records): (download)
    >2grpB (B:)
    padvstflafpspekllrlgpkssvliaqqtdtsdpekvvsaflkvssvfkdeatvrmav
    qdavdalmqkafnsssfnsntfltrllvhmgllksedkvkaianlygplmalnhmvqqdy
    fpkalaplllafvtkpnsalescsfarhsllqtlykv