SCOPe 2.05: Structural Classification of Proteins

PDB entry 2gpw

View 2gpw on RCSB PDB site
Description: Crystal Structure of the Biotin Carboxylase Subunit, F363A Mutant, of Acetyl-CoA Carboxylase from Escherichia coli.
Class: Ligase
Keywords: ATP-grasp, carboxylase, biotin-dependent, fatty acid synthesis, dimer-interface mutant, Ligase
Deposited on 2006-04-18, released 2006-07-04
The last revision prior to the SCOPe 2.05 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.192
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

Chain 'A':
Compound: biotin carboxylase
Species: Escherichia coli [TaxId:562]
Gene: accC
Database cross-references and differences (RAF-indexed):
- Uniprot P24182 (20-End)
  - cloning artifact (16-19)
  - engineered (382)
Domains in SCOPe 2.05: d2gpwa1, d2gpwa2, d2gpwa3
Chain 'B':
Compound: biotin carboxylase
Species: Escherichia coli [TaxId:562]
Gene: accC
Database cross-references and differences (RAF-indexed):
- Uniprot P24182 (20-End)
  - cloning artifact (16-19)
  - engineered (382)
Domains in SCOPe 2.05: d2gpwb1, d2gpwb2, d2gpwb3
Chain 'C':
Compound: biotin carboxylase
Species: Escherichia coli [TaxId:562]
Gene: accC
Database cross-references and differences (RAF-indexed):
- Uniprot P24182 (20-End)
  - cloning artifact (16-19)
  - engineered (382)
Domains in SCOPe 2.05: d2gpwc1, d2gpwc2, d2gpwc3
Chain 'D':
Compound: biotin carboxylase
Species: Escherichia coli [TaxId:562]
Gene: accC
Database cross-references and differences (RAF-indexed):
- Uniprot P24182 (20-End)
  - cloning artifact (15-19)
  - engineered (382)
Domains in SCOPe 2.05: d2gpwd1, d2gpwd2, d2gpwd3
Heterogens: HOH

PDB Chain Sequences:

Chain 'A':
Sequence, based on SEQRES records: (download)

>2gpwA (A:)
mgsshhhhhhssglvprgshmldkivianrgeialrilrackelgiktvavhssadrdlk
hvlladetvcigpapsvksylnipaiisaaeitgavaihpgygflsenanfaeqversgf
ifigpkaetirlmgdkvsaiaamkkagvpcvpgsdgplgddmdknraiakrigypviika
sgggggrgmrvvrgdaelaqsismtraeakaafsndmvymekylenprhveiqvladgqg
naiylaerdcsmqrrhqkvveeapapgitpelrryigercakacvdigyrgagtfeflfe
ngefyfiemntriqvehpvtemitgvdlikeqlriaagqplsikqeevhvrghavecrin
aedpntflpspgkitrfhapggagvrweshiyagytvppyydsmigklicygenrdvaia
rmknalqeliidgiktnvdlqirimndenfqhggtnihylekklglqek

Sequence, based on observed residues (ATOM records): (download)

>2gpwA (A:)
rgshmldkivianrgeialrilrackelgiktvavhssadrdlkhvlladetvcigpaps
vksylnipaiisaaeitgavaihpgygflsenanfaeqversgfifigpkaetirlmgdk
vsaiaamkkagvpcvpgsdgplgddmdknraiakrigypviikasggmrvvrgdaelaqs
ismtraeakaafndmvymekylenprhveiqvladgqgnaiylaerdcsmqrrhqkvvee
apapgitpelrryigercakacvdigyrgagtfeflfengefyfiemntriqvehpvtem
itgvdlikeqlriaagqplsikqeevhvrghavecrinaedpntflpspgkitrfhapgg
agvrweshiyagytvppyydsmigklicygenrdvaiarmknalqeliidgiktnvdlqi
rimndenfqhggtnihylekklglq

Chain 'B':
Sequence, based on SEQRES records: (download)

>2gpwB (B:)
mgsshhhhhhssglvprgshmldkivianrgeialrilrackelgiktvavhssadrdlk
hvlladetvcigpapsvksylnipaiisaaeitgavaihpgygflsenanfaeqversgf
ifigpkaetirlmgdkvsaiaamkkagvpcvpgsdgplgddmdknraiakrigypviika
sgggggrgmrvvrgdaelaqsismtraeakaafsndmvymekylenprhveiqvladgqg
naiylaerdcsmqrrhqkvveeapapgitpelrryigercakacvdigyrgagtfeflfe
ngefyfiemntriqvehpvtemitgvdlikeqlriaagqplsikqeevhvrghavecrin
aedpntflpspgkitrfhapggagvrweshiyagytvppyydsmigklicygenrdvaia
rmknalqeliidgiktnvdlqirimndenfqhggtnihylekklglqek

Sequence, based on observed residues (ATOM records): (download)

>2gpwB (B:)
rgshmldkivianrgeialrilrackelgiktvavhssadrdlkhvlladetvcigpaps
vksylnipaiisaaeitgavaihpgygflsenanfaeqversgfifigpkaetirlmgdk
vsaiaamkkagvpcvpgsdgplgddmdknraiakrigypviikasggmrvvrgdaelaqs
ismtraeakadmvymekylenprhveiqvladgqgnaiylaerdcsmqrrhqkvveeapa
pgitpelrryigercakacvdigyrgagtfeflfengefyfiemntriqvehpvtemitg
vdlikeqlriaagqplsikqeevhvrghavecrinaedpntflpspgkitrfhapggagv
rweshiyagytvppyydsmigklicygenrdvaiarmknalqeliidgiktnvdlqirim
ndenfqhggtnihylekklglq

Chain 'C':
Sequence, based on SEQRES records: (download)

>2gpwC (C:)
mgsshhhhhhssglvprgshmldkivianrgeialrilrackelgiktvavhssadrdlk
hvlladetvcigpapsvksylnipaiisaaeitgavaihpgygflsenanfaeqversgf
ifigpkaetirlmgdkvsaiaamkkagvpcvpgsdgplgddmdknraiakrigypviika
sgggggrgmrvvrgdaelaqsismtraeakaafsndmvymekylenprhveiqvladgqg
naiylaerdcsmqrrhqkvveeapapgitpelrryigercakacvdigyrgagtfeflfe
ngefyfiemntriqvehpvtemitgvdlikeqlriaagqplsikqeevhvrghavecrin
aedpntflpspgkitrfhapggagvrweshiyagytvppyydsmigklicygenrdvaia
rmknalqeliidgiktnvdlqirimndenfqhggtnihylekklglqek

Sequence, based on observed residues (ATOM records): (download)

>2gpwC (C:)
rgshmldkivianrgeialrilrackelgiktvavhssadrdlkhvlladetvcigpaps
vksylnipaiisaaeitgavaihpgygflsenanfaeqversgfifigpkaetirlmgdk
vsaiaamkkagvpcvpgsdgplgddmdknraiakrigypviikasggmrvvrgdaelaqs
ismtraeakaafsndmvymekylenprhveiqvladgqgnaiylaerdcsmqrrhqkvve
eapapgitpelrryigercakacvdigyrgagtfeflfengefyfiemntriqvehpvte
mitgvdlikeqlriaagqplsikqeevhvrghavecrinaedpntflpspgkitrfhapg
gagvrweshiyagytvppyydsmigklicygenrdvaiarmknalqeliidgiktnvdlq
irimndenfqhggtnihylekklglq

Chain 'D':
Sequence, based on SEQRES records: (download)

>2gpwD (D:)
mgsshhhhhhssglvprgshmldkivianrgeialrilrackelgiktvavhssadrdlk
hvlladetvcigpapsvksylnipaiisaaeitgavaihpgygflsenanfaeqversgf
ifigpkaetirlmgdkvsaiaamkkagvpcvpgsdgplgddmdknraiakrigypviika
sgggggrgmrvvrgdaelaqsismtraeakaafsndmvymekylenprhveiqvladgqg
naiylaerdcsmqrrhqkvveeapapgitpelrryigercakacvdigyrgagtfeflfe
ngefyfiemntriqvehpvtemitgvdlikeqlriaagqplsikqeevhvrghavecrin
aedpntflpspgkitrfhapggagvrweshiyagytvppyydsmigklicygenrdvaia
rmknalqeliidgiktnvdlqirimndenfqhggtnihylekklglqek

Sequence, based on observed residues (ATOM records): (download)

>2gpwD (D:)
prgshmldkivianrgeialrilrackelgiktvavhssadrdlkhvlladetvcigpap
svksylnipaiisaaeitgavaihpgygflsenanfaeqversgfifigpkaetirlmgd
kvsaiaamkkagvpcvpgsdgplgddmdknraiakrigypviikasggmrvvrgdaelaq
sismtraeakaafsndmvymekylenprhveiqvladgqgnaiylaerdcsmqrrhqkvv
eeapapgitpelrryigercakacvdigyrgagtfeflfengefyfiemntriqvehpvt
emitgvdlikeqlriaagqplsikqeevhvrghavecrinaedpntflpspgkitrfhap
ggagvrweshiyagytvppyydsmigklicygenrdvaiarmknalqeliidgiktnvdl
qirimndenfqhggtnihylekklglq