PDB entry 2gph

View 2gph on RCSB PDB site
Description: Docking motif interactions in the MAP kinase ERK2
Class: transferase
Keywords: ERK2, docking interaction, D-motif, allostery, CD-site, phosphatase-derived peptide, processing conformation, Transferase
Deposited on 2006-04-17, released 2006-07-04
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-10-18, with a file datestamp of 2017-10-13.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Mitogen-activated protein kinase 1
    Species: Rattus norvegicus [TaxId:10116]
    Gene: ERK2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P63086
      • engineered (121)
    Domains in SCOPe 2.08: d2gpha_
  • Chain 'B':
    Compound: Tyrosine-protein phosphatase non-receptor type 7
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • Uniprot P35236 (0-15)
      • engineered (15)
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2gphA (A:)
hhhhhhmaaaaaagpemvrgqvfdvgprytnlsyigegaygmvcsaydnlnkvrvaikki
spfehqtycqrtlreikillrfrheniigindiiraptieqmkdvyivqdlmetdlykll
kcqhlsndhicyflyqilrglkyihsanvlhrdlkpsnlllnttcdlkicdfglarvadp
dhdhtgflteyvatrwyrapeimlnskgytksidiwsvgcilaemlsnrpifpgkhyldq
lnhilgilgspsqedlnciinlkarnyllslphknkvpwnrlfpnadskaldlldkmltf
nphkrieveqalahpyleqyydpsdepiaeapfkfdmelddlpkeklkelifeetarfqp
gyrs

    Sequence, based on observed residues (ATOM records): (download) 
    >2gphA (A:)
emvrgqvfdvgprytnlsyigegaygmvcsaydnlnkvrvaikkispfehqtycqrtlre
ikillrfrheniigindiiraptieqmkdvyivqdlmetdlykllkcqhlsndhicyfly
qilrglkyihsanvlhrdlkpsnlllnttcdlkicdfglarvadpdhdhtgflteyvatr
wyrapeimlnskgytksidiwsvgcilaemlsnrpifpgkhyldqlnhilgilgspsqed
lnciinlkarnyllslphknkvpwnrlfpnadskaldlldkmltfnphkrieveqalahp
yleqyydpsdepiaeapfkfdmelddlpkeklkelifeetarfqp

  • Chain 'B':
    No sequence available.