PDB entry 2gp0

View 2gp0 on RCSB PDB site
Description: HePTP Catalytic Domain (residues 44-339), S225D mutant
Class: hydrolase
Keywords: HePTP, Human Hemapoietic Tyrosine Phosphatase Catalytic Domain, PTPN7, HYDROLASE
Deposited on 2006-04-15, released 2006-05-09
The last revision prior to the SCOPe 2.04 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-25.
Experiment type: XRAY
Resolution: 2.05 Å
R-factor: 0.179
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Tyrosine-protein phosphatase non-receptor type 7
    Species: Homo sapiens [TaxId:9606]
    Gene: PTPN7
    Database cross-references and differences (RAF-indexed):
    • Uniprot P35236 (13-End)
      • engineered (194)
    Domains in SCOPe 2.04: d2gp0a_
  • Heterogens: PO4, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2gp0A (A:)
    mgsdkihhhhhhmntprevtlhflrtaghpltrwalqrqppspkqleeeflkipsnfvsp
    edldipghaskdryktilpnpqsrvclgraqsqedgdyinanyirgydgkekvyiatqgp
    mpntvsdfwemvwqeevslivmltqlregkekcvhywpteeetygpfqiriqdmkecpey
    tvrqltiqyqeerrdvkhilfsawpdhqtpesagpllrlvaeveespetaahpgpivvhc
    sagigrtgcfiatrigcqqlkargevdilgivcqlrldrggmiqtaeqyqflhhtlalya
    gqlpeepsp
    

    Sequence, based on observed residues (ATOM records): (download)
    >2gp0A (A:)
    ntprevtlhflrtaghpltrwalqrqppspkqleeeflkipsnfvspedldipghaskdr
    yktilpnpqsrvclgraqsqedgdyinanyirgydgkekvyiatqgpmpntvsdfwemvw
    qeevslivmltqlrecvhywpteeetygpfqiriqdmkecpeytvrqltiqyqeerrdvk
    hilfsawpdhqtpesagpllrlvaeveespetaahpgpivvhcsagigrtgcfiatrigc
    qqlkargevdilgivcqlrldrggmiqtaeqyqflhhtlalyagqlpe