PDB entry 2goo

View 2goo on RCSB PDB site
Description: Ternary Complex of BMP-2 bound to BMPR-Ia-ECD and ActRII-ECD
Class: transferase
Keywords: TGF-beta, BMP-2, BMPR-Ia, ActRII, ALK-3,
Deposited on 2006-04-13, released 2006-05-09
The last revision prior to the SCOP 1.73 freeze date was dated 2006-05-09, with a file datestamp of 2007-06-28.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.224
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Bone morphogenetic protein 2
    Species: HOMO SAPIENS
    Gene: BMP2
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d2gooa1
  • Chain 'B':
    Compound: Bone morphogenetic protein receptor type IA
    Species: HOMO SAPIENS
    Gene: BMPR1A
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d2goob1
  • Chain 'C':
    Compound: Activin receptor type 2A
    Species: MUS MUSCULUS
    Gene: Acvr2a
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d2gooc1
  • Chain 'D':
    Compound: Bone morphogenetic protein 2
    Species: HOMO SAPIENS
    Gene: BMP2
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d2good1
  • Chain 'E':
    Compound: Bone morphogenetic protein receptor type IA
    Species: HOMO SAPIENS
    Gene: BMPR1A
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d2gooe1
  • Chain 'F':
    Compound: Activin receptor type 2A
    Species: MUS MUSCULUS
    Gene: Acvr2a
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d2goof1
  • Heterogens: NDG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2gooA (A:)
qakhkqrkrlkssckrhplyvdfsdvgwndwivappgyhafychgecpfpladhlnstnh
aivqtlvnsvnskipkaccvptelsaismlyldenekvvlknyqdmvvegcgcr

    Sequence, based on observed residues (ATOM records): (download) 
    >2gooA (A:)
ssckrhplyvdfsdvgwndwivappgyhafychgecpfpladhlnstnhaivqtlvnsvn
skipkaccvptelsaismlyldenekvvlknyqdmvvegcgcr

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2gooB (B:)
gsqnldsmlhgtgmksdsdqkksengvtlapedtlpflkcycsghcpddainntcitngh
cfaiieeddqgettlasgcmkyegsdfqckdspkaqlrrtieccrtnlcnqylqptlppv
vigpffdgsir

    Sequence, based on observed residues (ATOM records): (download) 
    >2gooB (B:)
pflkcycsghcpddainntcitnghcfaiieeddqgettlasgcmkyegsdfqckdspka
qlrrtieccrtnlcnqylqptlppv

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2gooC (C:)
ailgrsetqeclffnanwerdrtnqtgvepcygdkdkrrhcfatwknisgsieivkqgcw
lddincydrtdciekkdspevyfcccegnmcnekfsyfpeme

    Sequence, based on observed residues (ATOM records): (download) 
    >2gooC (C:)
tqeclffnanwerdrtnqtgvepcygdkdkrrhcfatwknisgsieivkqgcwlddincy
drtdciekkdspevyfcccegnmcnekfsyfp

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2gooD (D:)
qakhkqrkrlkssckrhplyvdfsdvgwndwivappgyhafychgecpfpladhlnstnh
aivqtlvnsvnskipkaccvptelsaismlyldenekvvlknyqdmvvegcgcr

    Sequence, based on observed residues (ATOM records): (download) 
    >2gooD (D:)
kssckrhplyvdfsdvgwndwivappgyhafychgecpfpladhlnstnhaivqtlvnsv
nskipkaccvptelsaismlyldenekvvlknyqdmvvegcgcr

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >2gooE (E:)
gsqnldsmlhgtgmksdsdqkksengvtlapedtlpflkcycsghcpddainntcitngh
cfaiieeddqgettlasgcmkyegsdfqckdspkaqlrrtieccrtnlcnqylqptlppv
vigpffdgsir

    Sequence, based on observed residues (ATOM records): (download) 
    >2gooE (E:)
lpflkcycsghcpddainntcitnghcfaiieeddqgettlasgcmkyegsdfqckdspk
aqlrrtieccrtnlcnqylqptlppvvi

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >2gooF (F:)
ailgrsetqeclffnanwerdrtnqtgvepcygdkdkrrhcfatwknisgsieivkqgcw
lddincydrtdciekkdspevyfcccegnmcnekfsyfpeme

    Sequence, based on observed residues (ATOM records): (download) 
    >2gooF (F:)
etqeclffnanwerdrtnqtgvepcygdkdkrrhcfatwknisgsieivkqgcwlddinc
ydrtdciekkdspevyfcccegnmcnekfsyfp