PDB entry 2go4

View 2go4 on RCSB PDB site
Description: Crystal structure of Aquifex aeolicus LpxC complexed with TU-514
Class: hydrolase
Keywords: LpxC-inhibitor complex
Deposited on 2006-04-12, released 2006-07-04
The last revision prior to the SCOP 1.73 freeze date was dated 2006-07-04, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: 0.21
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
    Species: Aquifex aeolicus
    Gene: lpxC, envA
    Database cross-references and differences (RAF-indexed):
    • Uniprot O67648 (Start-266)
      • engineered (180)
    Domains in SCOP 1.73: d2go4a1, d2go4a2
  • Chain 'B':
    Compound: UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
    Species: Aquifex aeolicus
    Gene: lpxC, envA
    Database cross-references and differences (RAF-indexed):
    • Uniprot O67648 (Start-266)
      • engineered (180)
    Domains in SCOP 1.73: d2go4b1, d2go4b2
  • Heterogens: ZN, CL, TUX, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2go4A (A:)
mglektvkeklsfegvgihtgeyskliihpekegtgirffkngvyiparhefvvhtnhst
dlgfkgqriktvehilsvlhlleitnvtievigneipildgsgwefyeairknilnqnre
idyfvveepiivedegrlikaepsdtlevtyegefknflgrqkftfvegneeeivlartf
afdweiehikkvglgkggslkntlvlgkdkvynpeglryenepvrhkvfdligdlyllgs
pvkgkfysfrgghslnvklvkelakkq

    Sequence, based on observed residues (ATOM records): (download) 
    >2go4A (A:)
glektvkeklsfegvgihtgeyskliihpekegtgirffkngvyiparhefvvhtnhstd
lgfkgqriktvehilsvlhlleitnvtievigneipildgsgwefyeairknilnqnrei
dyfvveepiivedegrlikaepsdtlevtyegefknflgrqkftfvegneeeivlartfa
fdweiehikkvglgkggslkntlvlgkdkvynpeglryenepvrhkvfdligdlyllgsp
vkgkfysfrgghslnvklvkelakkq

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2go4B (B:)
mglektvkeklsfegvgihtgeyskliihpekegtgirffkngvyiparhefvvhtnhst
dlgfkgqriktvehilsvlhlleitnvtievigneipildgsgwefyeairknilnqnre
idyfvveepiivedegrlikaepsdtlevtyegefknflgrqkftfvegneeeivlartf
afdweiehikkvglgkggslkntlvlgkdkvynpeglryenepvrhkvfdligdlyllgs
pvkgkfysfrgghslnvklvkelakkq

    Sequence, based on observed residues (ATOM records): (download) 
    >2go4B (B:)
glektvkeklsfegvgihtgeyskliihpekegtgirffkngvyiparhefvvhtnhstd
lgfkgqriktvehilsvlhlleitnvtievigneipildgsgwefyeairknilnqnrei
dyfvveepiivedegrlikaepsdtlevtyegefknflgrqkftfvegneeeivlartfa
fdweiehikkvglgkggslkntlvlgkdkvynpeglryenepvrhkvfdligdlyllgsp
vkgkfysfrgghslnvklvkelakkq