PDB entry 2gl7

View 2gl7 on RCSB PDB site
Description: Crystal Structure of a beta-catenin/BCL9/Tcf4 complex
Class: transcription
Keywords: protein complex, armadillo repeat, transcription
Deposited on 2006-04-04, released 2006-10-31
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.223
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: beta-catenin
    Species: Homo sapiens [TaxId:9606]
    Gene: CTNNB1, CTNNB
    Database cross-references and differences (RAF-indexed):
    • Uniprot P35222
      • engineered (5)
    Domains in SCOPe 2.08: d2gl7a_
  • Chain 'B':
    Compound: transcription factor 7-like 2
    Species: Homo sapiens [TaxId:9606]
    Gene: TCF7L2, TCF4
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: B-cell lymphoma 9 protein
    Species: Homo sapiens [TaxId:9606]
    Gene: BCL9
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: beta-catenin
    Species: Homo sapiens [TaxId:9606]
    Gene: CTNNB1, CTNNB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2gl7d_
  • Chain 'E':
    Compound: transcription factor 7-like 2
    Species: Homo sapiens [TaxId:9606]
    Gene: TCF7L2, TCF4
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: B-cell lymphoma 9 protein
    Species: Homo sapiens [TaxId:9606]
    Gene: BCL9
    Database cross-references and differences (RAF-indexed):
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2gl7A (A:)
snlineqddaelatraipeltkllndedqvvvnkaavmvhqlskkeasrhaimrspqmvs
aivrtmqntndvetarctagtlhnlshhregllaifksggipalvkmlgspvdsvlfyai
ttlhnlllhqegakmavrlagglqkmvallnktnvkflaittdclqilaygnqeskliil
asggpqalvnimrtytyekllwttsrvlkvlsvcssnkpaiveaggmqalglhltdpsqr
lvqnclwtlrnlsdaatkqegmegllgtlvqllgsddinvvtcaagilsnltcnnyknkm
mvcqvggiealvrtvlragdreditepaicalrhltsrhqeaemaqnavrlhyglpvvvk
llhppshwplikatvglirnlalcpanhaplreqgaiprlvqllvrahqdtqrrtsmggt
qqqfvegvrmeeivegctgalhilardvhnrivirglntiplfvqllyspieniqrvaag
vlcelaqdkeaaeaieaegatapltellhsrnegvatyaaavlfrmsedkpqdykkrlsv
eltsslfrte

    Sequence, based on observed residues (ATOM records): (download) 
    >2gl7A (A:)
eqddaelatraipeltkllndedqvvvnkaavmvhqlskkeasrhaimrspqmvsaivrt
mqntndvetarctagtlhnlshhregllaifksggipalvkmlgspvdsvlfyaittlhn
lllhqegakmavrlagglqkmvallnktnvkflaittdclqilaygnqeskliilasggp
qalvnimrtytyekllwttsrvlkvlsvcssnkpaiveaggmqalglhltdpsqrlvqnc
lwtlrnlsdaatkqegmegllgtlvqllgsddinvvtcaagilsnltcnnyknkmmvcqv
ggiealvrtvlragdreditepaicalrhltsrhqeaemaqnavrlhyglpvvvkllhpp
shwplikatvglirnlalcpanhaplreqgaiprlvqllvrahqdtqrfvegvrmeeive
gctgalhilardvhnrivirglntiplfvqllyspieniqrvaagvlcelaqdkeaaeai
eaegatapltellhsrnegvatyaaavlfrms

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2gl7D (D:)
snlineqddaelatraipeltkllndedqvvvnkaavmvhqlskkeasrhaimrspqmvs
aivrtmqntndvetarctagtlhnlshhregllaifksggipalvkmlgspvdsvlfyai
ttlhnlllhqegakmavrlagglqkmvallnktnvkflaittdclqilaygnqeskliil
asggpqalvnimrtytyekllwttsrvlkvlsvcssnkpaiveaggmqalglhltdpsqr
lvqnclwtlrnlsdaatkqegmegllgtlvqllgsddinvvtcaagilsnltcnnyknkm
mvcqvggiealvrtvlragdreditepaicalrhltsrhqeaemaqnavrlhyglpvvvk
llhppshwplikatvglirnlalcpanhaplreqgaiprlvqllvrahqdtqrrtsmggt
qqqfvegvrmeeivegctgalhilardvhnrivirglntiplfvqllyspieniqrvaag
vlcelaqdkeaaeaieaegatapltellhsrnegvatyaaavlfrmsedkpqdykkrlsv
eltsslfrte

    Sequence, based on observed residues (ATOM records): (download) 
    >2gl7D (D:)
elatraipeltkllndedqvvvnkaavmvhqlskkeasrhaimrspqmvsaivrtmqntn
dvetarctagtlhnlshhregllaifksggipalvkmlgspvdsvlfyaittlhnlllhq
egakmavrlagglqkmvallnktnvkflaittdclqilaygnqeskliilasggpqalvn
imrtytyekllwttsrvlkvlsvcssnkpaiveaggmqalglhltdpsqrlvqnclwtlr
nlsdaatkqegmegllgtlvqllgsddinvvtcaagilsnltcnnyknkmmvcqvggiea
lvrtvlragdreditepaicalrhltsrhqeaemaqnavrlhyglpvvvkllhppshwpl
ikatvglirnlalcpanhaplreqgaiprlvqllvrahqdtqrfvegvrmeeivegctga
lhilardvhnrivirglntiplfvqllyspieniqrvaagvlcelaqdkeaaeaieaega
tapltellhsrnegvatyaaavlfrm

  • Chain 'E':
    No sequence available.

  • Chain 'F':
    No sequence available.