PDB entry 2gix

View 2gix on RCSB PDB site
Description: Cytoplasmic Domain Structure of Kir2.1 containing Andersen's Mutation R218Q and Rescue Mutation T309K
Class: metal transport
Keywords: Cytoplasmic Domains of Kir2.1, Andersen's Mutation, METAL TRANSPORT
Deposited on 2006-03-29, released 2006-07-25
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-10-18, with a file datestamp of 2017-10-13.
Experiment type: XRAY
Resolution: 2.02 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Inward rectifier potassium channel 2
    Species: Mus musculus [TaxId:10090]
    Gene: Kcnj2, Irk1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P35561 (25-End)
      • engineered (54)
      • engineered (145)
      • cloning artifact (1-3)
    • Uniprot P35561 (4-24)
    Domains in SCOPe 2.07: d2gixa1, d2gixa2
  • Chain 'B':
    Compound: Inward rectifier potassium channel 2
    Species: Mus musculus [TaxId:10090]
    Gene: Kcnj2, Irk1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P35561 (25-End)
      • engineered (54)
      • engineered (145)
      • cloning artifact (1-3)
    • Uniprot P35561 (4-24)
    Domains in SCOPe 2.07: d2gixb1, d2gixb2
  • Chain 'C':
    Compound: Inward rectifier potassium channel 2
    Species: Mus musculus [TaxId:10090]
    Gene: Kcnj2, Irk1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P35561 (25-End)
      • engineered (54)
      • engineered (145)
      • cloning artifact (1-3)
    • Uniprot P35561 (4-24)
    Domains in SCOPe 2.07: d2gixc1, d2gixc2
  • Chain 'D':
    Compound: Inward rectifier potassium channel 2
    Species: Mus musculus [TaxId:10090]
    Gene: Kcnj2, Irk1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P35561 (25-End)
      • engineered (54)
      • engineered (145)
      • cloning artifact (1-3)
    • Uniprot P35561 (4-24)
    Domains in SCOPe 2.07: d2gixd1, d2gixd2
  • Heterogens: K, MPD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2gixA (A:)
gshgrsrfvkkdghcnvqfinvgekrnetlvfshnaviamrdgklclmwrvgnlqkshlv
eahvraqllksritsegeyipldqidinvgfdsgidriflvspitivheidedsplydls
kqdidnadfeivvilegmveatamtkqcrssylaneilwghryepvlfeekhyykvdysr
fhktyevpntplcsardlaekkyilsna

    Sequence, based on observed residues (ATOM records): (download) 
    >2gixA (A:)
shgrsrfvkkdghcnvqfinvgekrnetlvfshnaviamrdgklclmwrvgnlqkshlve
ahvraqllksritsegeyipldqidinvgfdsgidriflvspitivheidedsplydlsk
qdidnadfeivvilegmveatamtkqcrssylaneilwghryepvlfeekhyykvdysrf
hktyevpntplcsardlaekkyilsn

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2gixB (B:)
gshgrsrfvkkdghcnvqfinvgekrnetlvfshnaviamrdgklclmwrvgnlqkshlv
eahvraqllksritsegeyipldqidinvgfdsgidriflvspitivheidedsplydls
kqdidnadfeivvilegmveatamtkqcrssylaneilwghryepvlfeekhyykvdysr
fhktyevpntplcsardlaekkyilsna

    Sequence, based on observed residues (ATOM records): (download) 
    >2gixB (B:)
shgrsrfvkkdghcnvqfinvgekrnetlvfshnaviamrdgklclmwrvgnlqkshlve
ahvraqllksritsegeyipldqidinvgfdsgidriflvspitivheidedsplydlsk
qdidnadfeivvilegmveatamtkqcrssylaneilwghryepvlfeekhyykvdysrf
hktyevpntplcsardlaekk

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2gixC (C:)
gshgrsrfvkkdghcnvqfinvgekrnetlvfshnaviamrdgklclmwrvgnlqkshlv
eahvraqllksritsegeyipldqidinvgfdsgidriflvspitivheidedsplydls
kqdidnadfeivvilegmveatamtkqcrssylaneilwghryepvlfeekhyykvdysr
fhktyevpntplcsardlaekkyilsna

    Sequence, based on observed residues (ATOM records): (download) 
    >2gixC (C:)
shgrsrfvkkdghcnvqfinvgekrnetlvfshnaviamrdgklclmwrvgnlqkshlve
ahvraqllksritsegeyipldqidinvgfdsgidriflvspitivheidedsplydlsk
qdidnadfeivvilegmveatamtkqcrssylaneilwghryepvlfeekhyykvdysrf
hktyevpntplcsardlaekkyilsn

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2gixD (D:)
gshgrsrfvkkdghcnvqfinvgekrnetlvfshnaviamrdgklclmwrvgnlqkshlv
eahvraqllksritsegeyipldqidinvgfdsgidriflvspitivheidedsplydls
kqdidnadfeivvilegmveatamtkqcrssylaneilwghryepvlfeekhyykvdysr
fhktyevpntplcsardlaekkyilsna

    Sequence, based on observed residues (ATOM records): (download) 
    >2gixD (D:)
shgrsrfvkkdghcnvqfinvgekrnetlvfshnaviamrdgklclmwrvgnlqkshlve
ahvraqllksritsegeyipldqidinvgfdsgidriflvspitivheidedsplydlsk
qdidnadfeivvilegmveatamtkqcrssylaneilwghryepvlfeekhyykvdysrf
hktyevpntplcsardlaekkyils