PDB entry 2ghw

View 2ghw on RCSB PDB site
Description: Crystal structure of SARS spike protein receptor binding domain in complex with a neutralizing antibody, 80R
Class: virus/viral protein/antibiotic
Keywords: SARS, S protein, neutralizing antibody, VIRUS/VIRAL PROTEIN/ANTIBIOTIC COMPLEX
Deposited on 2006-03-27, released 2006-09-19
The last revision prior to the SCOPe 2.01 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.251
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Spike glycoprotein
    Species: SARS coronavirus [TaxId:227859]
    Gene: S
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d2ghwa_
  • Chain 'B':
    Compound: anti-sars scFv antibody, 80R
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d2ghwb1, d2ghwb2
  • Chain 'C':
    Compound: Spike glycoprotein
    Species: SARS coronavirus [TaxId:227859]
    Gene: S
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d2ghwc_
  • Chain 'D':
    Compound: anti-sars scFv antibody, 80R
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d2ghwd1, d2ghwd2
  • Heterogens: CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2ghwA (A:)
madpnitnlcpfgevfnatkfpsvyawerkkisncvadysvlynstffstfkcygvsatk
lndlcfsnvyadsfvvkgddvrqiapgqtgviadynyklpddfmgcvlawntrnidatst
gnynykyrylrhgklrpferdisnvpfspdgkpctppalncywplndygfytttgigyqp
yrvvvlsfellnapatvsglvpr

    Sequence, based on observed residues (ATOM records): (download) 
    >2ghwA (A:)
itnlcpfgevfnatkfpsvyawerkkisncvadysvlynstffstfkcygvsatklndlc
fsnvyadsfvvkgddvrqiapgqtgviadynyklpddfmgcvlawntrnidatstgnyny
kyrylrhgklrpferdisnvpfspdgkpctppalncywplndygfytttgigyqpyrvvv
lsfellnapat

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2ghwB (B:)
maevqlvqsgggvvqpgkslrlscaasgfafssyamhwvrqapgkglewvavisydgsnk
yyadsvkgrftisrdnskntlylqmnslraedtavyycardrsyyldywgqgtlvtvssg
gggsggggsggggsettltqspatlslspgeratlscrasqsvrsnlawyqqkpgqaprp
liydastratgipdrfsgsgsgtdftltisrlepedfavyycqqrsnwpptfgqgtkvev
ksglvpr

    Sequence, based on observed residues (ATOM records): (download) 
    >2ghwB (B:)
evqlvqsgggvvqpgkslrlscaasgfafssyamhwvrqapgkglewvavisydgsnkyy
adsvkgrftisrdnskntlylqmnslraedtavyycardrsyyldywgqgtlvtvssggs
ettltqspatlslspgeratlscrasqsvrsnlawyqqkpgqaprpliydastratgipd
rfsgsgsgtdftltisrlepedfavyycqqrsnwpptfgqgtkvevksglvp

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2ghwC (C:)
madpnitnlcpfgevfnatkfpsvyawerkkisncvadysvlynstffstfkcygvsatk
lndlcfsnvyadsfvvkgddvrqiapgqtgviadynyklpddfmgcvlawntrnidatst
gnynykyrylrhgklrpferdisnvpfspdgkpctppalncywplndygfytttgigyqp
yrvvvlsfellnapatvsglvpr

    Sequence, based on observed residues (ATOM records): (download) 
    >2ghwC (C:)
nitnlcpfgevfnatkfpsvyawerkkisncvadysvlynstffstfkcygvsatklndl
cfsnvyadsfvvkgddvrqiapgqtgviadynyklpddfmgcvlawntrnidatstgnyn
ykyrylrhgklrpferdisnvpfspdgkpctppalncywplndygfytttgigyqpyrvv
vlsfelln

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2ghwD (D:)
maevqlvqsgggvvqpgkslrlscaasgfafssyamhwvrqapgkglewvavisydgsnk
yyadsvkgrftisrdnskntlylqmnslraedtavyycardrsyyldywgqgtlvtvssg
gggsggggsggggsettltqspatlslspgeratlscrasqsvrsnlawyqqkpgqaprp
liydastratgipdrfsgsgsgtdftltisrlepedfavyycqqrsnwpptfgqgtkvev
ksglvpr

    Sequence, based on observed residues (ATOM records): (download) 
    >2ghwD (D:)
evqlvqsgggvvqpgkslrlscaasgfafssyamhwvrqapgkglewvavisydgsnkyy
adsvkgrftisrdnskntlylqmnslraedtavyycardrsyyldywgqgtlvtvssset
tltqspatlslspgeratlscrasqsvrsnlawyqqkpgqaprpliydastratgipdrf
sgsgsgtdftltisrlepedfavyycqqrsnwpptfgqgtkvevksglvpr