PDB entry 2ghp

View 2ghp on RCSB PDB site
Description: Crystal structure of the N-terminal 3 RNA binding domains of the yeast splicing factor Prp24
Class: RNA binding protein
Keywords: RNA chaperone, RNA binding domain, RNA recognition motif, splicing factor, snRNP, spliceosome, Structural Genomics, Protein Structure Initiative, PSI, Center for Eukaryotic Structural Genomics, CESG, RNA BINDING PROTEIN
Deposited on 2006-03-27, released 2006-04-25
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-10-18, with a file datestamp of 2017-10-13.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: N/A
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: U4/U6 snRNA-associated splicing factor PRP24
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: PRP24
    Database cross-references and differences (RAF-indexed):
    • Uniprot P49960 (Start-291)
      • modified residue (121)
      • modified residue (213)
      • modified residue (258)
      • modified residue (272)
    Domains in SCOPe 2.07: d2ghpa1, d2ghpa2, d2ghpa3
  • Chain 'B':
    Compound: U4/U6 snRNA-associated splicing factor PRP24
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: PRP24
    Database cross-references and differences (RAF-indexed):
    • Uniprot P49960 (Start-291)
      • modified residue (121)
      • modified residue (213)
      • modified residue (258)
      • modified residue (272)
    Domains in SCOPe 2.07: d2ghpb1, d2ghpb2, d2ghpb3
  • Chain 'C':
    Compound: U4/U6 snRNA-associated splicing factor PRP24
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: PRP24
    Database cross-references and differences (RAF-indexed):
    • Uniprot P49960 (Start-291)
      • modified residue (121)
      • modified residue (213)
      • modified residue (258)
      • modified residue (272)
    Domains in SCOPe 2.07: d2ghpc1, d2ghpc2, d2ghpc3
  • Chain 'D':
    Compound: U4/U6 snRNA-associated splicing factor PRP24
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: PRP24
    Database cross-references and differences (RAF-indexed):
    • Uniprot P49960 (Start-291)
      • modified residue (121)
      • modified residue (213)
      • modified residue (258)
      • modified residue (272)
    Domains in SCOPe 2.07: d2ghpd1, d2ghpd2, d2ghpd3
  • Chain 'E':
    Compound: U4/U6 snRNA-associated splicing factor PRP24
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: PRP24
    Database cross-references and differences (RAF-indexed):
    • Uniprot P49960 (Start-291)
      • modified residue (121)
      • modified residue (213)
      • modified residue (258)
      • modified residue (272)
    Domains in SCOPe 2.07: d2ghpe1, d2ghpe2, d2ghpe3
  • Chain 'F':
    Compound: U4/U6 snRNA-associated splicing factor PRP24
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: PRP24
    Database cross-references and differences (RAF-indexed):
    • Uniprot P49960 (Start-291)
      • modified residue (121)
      • modified residue (213)
      • modified residue (258)
      • modified residue (272)
    Domains in SCOPe 2.07: d2ghpf1, d2ghpf2, d2ghpf3
  • Chain 'G':
    Compound: U4/U6 snRNA-associated splicing factor PRP24
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: PRP24
    Database cross-references and differences (RAF-indexed):
    • Uniprot P49960 (Start-291)
      • modified residue (121)
      • modified residue (213)
      • modified residue (258)
      • modified residue (272)
    Domains in SCOPe 2.07: d2ghpg1, d2ghpg2, d2ghpg3
  • Chain 'H':
    Compound: U4/U6 snRNA-associated splicing factor PRP24
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: PRP24
    Database cross-references and differences (RAF-indexed):
    • Uniprot P49960 (Start-291)
      • modified residue (121)
      • modified residue (213)
      • modified residue (258)
      • modified residue (272)
    Domains in SCOPe 2.07: d2ghph1, d2ghph2, d2ghph3
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2ghpA (A:)
smeyghharpdskrpldegspaaagltskkanealtrnrelttvlvknlpksynqnkvyk
yfkhcgpiihvdvadslkknfrfariefarydgalaaitkthkvvgqneiivshltectl
wmtnfppsytqrnirdllqdinvvalsirlpslrfntsrrfayidvtskedarycvekln
glkiegytlvtkvsnplekskrtdsatlegreimirnlstelldenllresfegfgsiek
inipagqkehsfnnccafmvfenkdsaeralqmnrsllgnreisvsladkkp

    Sequence, based on observed residues (ATOM records): (download) 
    >2ghpA (A:)
ttvlvknlpksynqnkvykyfkhcgpiihvdvadslkknfrfariefarydgalaaitkt
hkvvgqneiivshltectlwmtnfppsytqrnirdllqdinvvalsirlprrfayidvts
kedarycveklnglkiegytlvtkvsnpltlegreimirnlstelldenllresfegfgs
iekinipagqkfnnccafmvfenkdsaeralqmnrsllgnreisvsladkkp

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2ghpB (B:)
smeyghharpdskrpldegspaaagltskkanealtrnrelttvlvknlpksynqnkvyk
yfkhcgpiihvdvadslkknfrfariefarydgalaaitkthkvvgqneiivshltectl
wmtnfppsytqrnirdllqdinvvalsirlpslrfntsrrfayidvtskedarycvekln
glkiegytlvtkvsnplekskrtdsatlegreimirnlstelldenllresfegfgsiek
inipagqkehsfnnccafmvfenkdsaeralqmnrsllgnreisvsladkkp

    Sequence, based on observed residues (ATOM records): (download) 
    >2ghpB (B:)
ttvlvknlpksynqnkvykyfkhcgpiihvdvadslkknfrfariefarydgalaaitkt
hkvvgqneiivshltectlwmtnfppsytqrnirdllqdinvvalsirlpslrfntsrrf
ayidvtskedarycveklnglkiegytlvtkvsnpltlegreimirnlstelldenllre
sfegfgsiekinipagqkfnnccafmvfenkdsaeralqmnrsllgnreisvsladkkp

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2ghpC (C:)
smeyghharpdskrpldegspaaagltskkanealtrnrelttvlvknlpksynqnkvyk
yfkhcgpiihvdvadslkknfrfariefarydgalaaitkthkvvgqneiivshltectl
wmtnfppsytqrnirdllqdinvvalsirlpslrfntsrrfayidvtskedarycvekln
glkiegytlvtkvsnplekskrtdsatlegreimirnlstelldenllresfegfgsiek
inipagqkehsfnnccafmvfenkdsaeralqmnrsllgnreisvsladkkp

    Sequence, based on observed residues (ATOM records): (download) 
    >2ghpC (C:)
ttvlvknlpksynqnkvykyfkhcgpiihvdvadslkknfrfariefarydgalaaitkt
hkvvgqneiivshltectlwmtnfppsytqrnirdllqdinvvalsirlprrfayidvts
kedarycveklnglkiegytlvtkvsnpltlegreimirnlstelldenllresfegfgs
iekinipagqkfnnccafmvfenkdsaeralqmnrsllgnreisvsladkkp

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2ghpD (D:)
smeyghharpdskrpldegspaaagltskkanealtrnrelttvlvknlpksynqnkvyk
yfkhcgpiihvdvadslkknfrfariefarydgalaaitkthkvvgqneiivshltectl
wmtnfppsytqrnirdllqdinvvalsirlpslrfntsrrfayidvtskedarycvekln
glkiegytlvtkvsnplekskrtdsatlegreimirnlstelldenllresfegfgsiek
inipagqkehsfnnccafmvfenkdsaeralqmnrsllgnreisvsladkkp

    Sequence, based on observed residues (ATOM records): (download) 
    >2ghpD (D:)
ttvlvknlpksynqnkvykyfkhcgpiihvdvadslkknfrfariefarydgalaaitkt
hkvvgqneiivshltectlwmtnfppsytqrnirdllqdinvvalsirlprrfayidvts
kedarycveklnglkiegytlvtkvsnpltlegreimirnlstelldenllresfegfgs
iekinipagqkfnnccafmvfenkdsaeralqmnrsllgnreisvsladkkp

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >2ghpE (E:)
smeyghharpdskrpldegspaaagltskkanealtrnrelttvlvknlpksynqnkvyk
yfkhcgpiihvdvadslkknfrfariefarydgalaaitkthkvvgqneiivshltectl
wmtnfppsytqrnirdllqdinvvalsirlpslrfntsrrfayidvtskedarycvekln
glkiegytlvtkvsnplekskrtdsatlegreimirnlstelldenllresfegfgsiek
inipagqkehsfnnccafmvfenkdsaeralqmnrsllgnreisvsladkkp

    Sequence, based on observed residues (ATOM records): (download) 
    >2ghpE (E:)
ttvlvknlpksynqnkvykyfkhcgpiihvdvadslkknfrfariefarydgalaaitkt
hkvvgqneiivshltectlwmtnfppsytqrnirdllqdinvvalsirlprrfayidvts
kedarycveklnglkiegytlvtkvsnpltlegreimirnlstelldenllresfegfgs
iekinipagqkfnnccafmvfenkdsaeralqmnrsllgnreisvsladkkp

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >2ghpF (F:)
smeyghharpdskrpldegspaaagltskkanealtrnrelttvlvknlpksynqnkvyk
yfkhcgpiihvdvadslkknfrfariefarydgalaaitkthkvvgqneiivshltectl
wmtnfppsytqrnirdllqdinvvalsirlpslrfntsrrfayidvtskedarycvekln
glkiegytlvtkvsnplekskrtdsatlegreimirnlstelldenllresfegfgsiek
inipagqkehsfnnccafmvfenkdsaeralqmnrsllgnreisvsladkkp

    Sequence, based on observed residues (ATOM records): (download) 
    >2ghpF (F:)
ttvlvknlpksynqnkvykyfkhcgpiihvdvadslkknfrfariefarydgalaaitkt
hkvvgqneiivshltectlwmtnfppsytqrnirdllqdinvvalsirlpslrfntsrrf
ayidvtskedarycveklnglkiegytlvtkvsnpltlegreimirnlstelldenllre
sfegfgsiekinipagqkfnnccafmvfenkdsaeralqmnrsllgnreisvsladkkp

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >2ghpG (G:)
smeyghharpdskrpldegspaaagltskkanealtrnrelttvlvknlpksynqnkvyk
yfkhcgpiihvdvadslkknfrfariefarydgalaaitkthkvvgqneiivshltectl
wmtnfppsytqrnirdllqdinvvalsirlpslrfntsrrfayidvtskedarycvekln
glkiegytlvtkvsnplekskrtdsatlegreimirnlstelldenllresfegfgsiek
inipagqkehsfnnccafmvfenkdsaeralqmnrsllgnreisvsladkkp

    Sequence, based on observed residues (ATOM records): (download) 
    >2ghpG (G:)
ttvlvknlpksynqnkvykyfkhcgpiihvdvadslkknfrfariefarydgalaaitkt
hkvvgqneiivshltectlwmtnfppsytqrnirdllqdinvvalsirlprrfayidvts
kedarycveklnglkiegytlvtkvsnpltlegreimirnlstelldenllresfegfgs
iekinipagqkfnnccafmvfenkdsaeralqmnrsllgnreisvsladkkp

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >2ghpH (H:)
smeyghharpdskrpldegspaaagltskkanealtrnrelttvlvknlpksynqnkvyk
yfkhcgpiihvdvadslkknfrfariefarydgalaaitkthkvvgqneiivshltectl
wmtnfppsytqrnirdllqdinvvalsirlpslrfntsrrfayidvtskedarycvekln
glkiegytlvtkvsnplekskrtdsatlegreimirnlstelldenllresfegfgsiek
inipagqkehsfnnccafmvfenkdsaeralqmnrsllgnreisvsladkkp

    Sequence, based on observed residues (ATOM records): (download) 
    >2ghpH (H:)
ttvlvknlpksynqnkvykyfkhcgpiihvdvadslkknfrfariefarydgalaaitkt
hkvvgqneiivshltectlwmtnfppsytqrnirdllqdinvvalsirlprrfayidvts
kedarycveklnglkiegytlvtkvsnpltlegreimirnlstelldenllresfegfgs
iekinipagqkfnnccafmvfenkdsaeralqmnrsllgnreisvsladkkp