PDB entry 2gfo

View 2gfo on RCSB PDB site
Description: Structure of the Catalytic Domain of Human Ubiquitin Carboxyl-terminal Hydrolase 8
Class: hydrolase
Keywords: Hydrolase, Protease, Thiol protease, Ubl conjugation pathway, Deubiquitinating Enzyme, DUB, Zinc ribbon, Structural Genomics Consortium, SGC
Deposited on 2006-03-22, released 2006-04-04
The last revision prior to the SCOPe 2.01 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.171
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ubiquitin carboxyl-terminal hydrolase 8
    Species: Homo sapiens [TaxId:9606]
    Gene: USP8, KIAA0055, UBPY
    Database cross-references and differences (RAF-indexed):
    • Uniprot P40818
      • modified residue (73)
      • modified residue (119)
      • modified residue (162)
      • modified residue (235)
    Domains in SCOPe 2.01: d2gfoa1
  • Heterogens: ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2gfoA (A:)
mgsshhhhhhssglvprgsptvtptvnrenkptcypkaeisrlsasqirnlnpvfggsgp
altglrnlgntcymnsilqclcnaphladyfnrncyqddinrsnllghkgevaeefgiim
kalwtgqyryispkdfkitigkindqfagysqqdsqelllflmdglhedlnkadnrkryk
eenndhlddfkaaehawqkhkqlnesiivalfqgqfkstvqcltchkksrtfeafmylsl
plastskctlqdclrlfskeekltdnnrfycshcrarrdslkkieiwklppvllvhlkrf
sydgrwkqklqtsvdfplenldlsqyvigpknnlkkynlfsvsnhyggldgghytayckn
aarqrwfkfddhevsdisvssvkssaayilfytslg

    Sequence, based on observed residues (ATOM records): (download) 
    >2gfoA (A:)
irnlnpvfggsgpaltglrnlgntcymnsilqclcnaphladyfnrncyqddinrsnllg
hkgevaeefgiimkalwtgqyryispkdfkitigkindqfagysqqdsqelllflmdglh
edlnkadndhlddfkaaehawqkhkqlnesiivalfqgqfkstvqcltchkksrtfeafm
ylslplastskctlqdclrlfskeekltdnnrfycshcrarrdslkkieiwklppvllvh
lkrfsydgrwkqklqtsvdfplenldlsqyvigpknnlkkynlfsvsnhyggldgghyta
ycknaarqrwfkfddhevsdisvssvkssaayilfytsl