PDB entry 2gfd

View 2gfd on RCSB PDB site
Description: GRP94 in complex with the novel HSP90 Inhibitor Radamide
Class: chaperone
Keywords: GRP94, HSP82, HSP90, HTPG, chaperone, ligand, radicicol, geldanamycin, radester, radamide
Deposited on 2006-03-21, released 2007-04-03
The last revision prior to the SCOP 1.73 freeze date was dated 2007-04-03, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.211
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Endoplasmin
    Species: Canis familiaris
    Gene: TRA1
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d2gfda1
  • Chain 'B':
    Compound: Endoplasmin
    Species: Canis familiaris
    Gene: TRA1
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d2gfdb1
  • Heterogens: RDA, PG4, 1PE, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2gfdA (A:)
gshmlreksekfafqaevnrmmkliinslyknkeiflrelisnasdaldkirlisltden
alagneeltvkikcdkeknllhvtdtgvgmtreelvknlgtiaksgtseflnkmteaqed
gqstseligqfgvgfysaflvadkvivtskhnndtqhiwesdsnefsviadprgntlgrg
ttitlvlkeeasdyleldtiknlvkkysqfinfpiyvwssktggggktvwdwelmn

    Sequence, based on observed residues (ATOM records): (download) 
    >2gfdA (A:)
ekfafqaevnrmmkliinslyknkeiflrelisnasdaldkirlisltdenalagneelt
vkikcdkeknllhvtdtgvgmtreelvknlgtikgtseflnkmtestseligqfgvgfys
aflvadkvivtskhnndtqhiwesdsnefsviadprgntlgrgttitlvlkeeasdylel
dtiknlvkkysqfinfpiyvwssktktvwdwelmn

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2gfdB (B:)
gshmlreksekfafqaevnrmmkliinslyknkeiflrelisnasdaldkirlisltden
alagneeltvkikcdkeknllhvtdtgvgmtreelvknlgtiaksgtseflnkmteaqed
gqstseligqfgvgfysaflvadkvivtskhnndtqhiwesdsnefsviadprgntlgrg
ttitlvlkeeasdyleldtiknlvkkysqfinfpiyvwssktggggktvwdwelmn

    Sequence, based on observed residues (ATOM records): (download) 
    >2gfdB (B:)
ekfafqaevnrmmkliinslyknkeiflrelisnasdaldkirlisltdenalagneelt
vkikcdkeknllhvtdtgvgmtreelvknlgtiagtseflnkmteaqstseligqfgvgf
ysaflvadkvivtskhnndtqhiwesdsnefsviadprgntlgrgttitlvlkeeasdyl
eldtiknlvkkysqfinfpiyvwssktktvwdwelmn