PDB entry 2g9n

View 2g9n on RCSB PDB site
Description: Structure of the DEAD domain of Human eukaryotic initiation factor 4A, eIF4A
Class: hydrolase
Keywords: DEAD-box, Helicase, DDX2A, RNA, Structural Genomics, Structural Genomics Consortium, SGC, HYDROLASE
Deposited on 2006-03-07, released 2006-03-14
The last revision prior to the SCOPe 2.08 freeze date was dated 2010-10-27, with a file datestamp of 2010-10-22.
Experiment type: XRAY
Resolution: 2.25 Å
R-factor: 0.18
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Eukaryotic initiation factor 4A-I
    Species: Homo sapiens [TaxId:9606]
    Gene: EIF4A1, DDX2A, EIF4A
    Database cross-references and differences (RAF-indexed):
    • Uniprot P60842 (Start-220)
      • modified residue (36)
      • modified residue (50)
      • modified residue (64)
      • modified residue (81)
      • modified residue (100)
      • modified residue (128)
      • modified residue (156)
      • modified residue (159)
      • modified residue (175)
      • modified residue (184)
      • modified residue (207-208)
      • modified residue (219-220)
    Domains in SCOPe 2.08: d2g9na1
  • Chain 'B':
    Compound: Eukaryotic initiation factor 4A-I
    Species: Homo sapiens [TaxId:9606]
    Gene: EIF4A1, DDX2A, EIF4A
    Database cross-references and differences (RAF-indexed):
    • Uniprot P60842
      • modified residue (36)
      • modified residue (50)
      • modified residue (64)
      • modified residue (81)
      • modified residue (100)
      • modified residue (128)
      • modified residue (156)
      • modified residue (159)
      • modified residue (175)
      • modified residue (184)
      • modified residue (207-208)
      • modified residue (219)
    Domains in SCOPe 2.08: d2g9nb_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2g9nA (A:)
smegviesnwneivdsfddmnlsesllrgiyaygfekpsaiqqrailpcikgydviaqaq
sgtgktatfaisilqqieldlkatqalvlaptrelaqqiqkvvmalgdymgaschacigg
tnvraevqklqmeaphiivgtpgrvfdmlnrrylspkyikmfvldeademlsrgfkdqiy
difqklnsntqvvllsatmpsdvlevtkkfmrdpirilvkk

    Sequence, based on observed residues (ATOM records): (download) 
    >2g9nA (A:)
gviesnwneivdsfddmnlsesllrgiyaygfekpsaiqqrailpcikgydviaqaqsgt
gktatfaisilqqieldlkatqalvlaptrelaqqiqkvvmalgdymgaschacignvra
evqklqmeaphiivgtpgrvfdmlnrrylspkyikmfvldeademlsrgfkdqiydifqk
lnsntqvvllsatmpsdvlevtkkfmrdpirilvkk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2g9nB (B:)
smegviesnwneivdsfddmnlsesllrgiyaygfekpsaiqqrailpcikgydviaqaq
sgtgktatfaisilqqieldlkatqalvlaptrelaqqiqkvvmalgdymgaschacigg
tnvraevqklqmeaphiivgtpgrvfdmlnrrylspkyikmfvldeademlsrgfkdqiy
difqklnsntqvvllsatmpsdvlevtkkfmrdpirilvkk

    Sequence, based on observed residues (ATOM records): (download) 
    >2g9nB (B:)
iesnwneivdsfddmnlsesllrgiyaygfekpsaiqqrailpcikgydviaqaqsgtgk
tatfaisilqqieldlkatqalvlaptrelaqqiqkvvmalgdymgaschaciggtnvra
evqklqmeaphiivgtpgrvfdmlnrrylspkyikmfvldeademlsrgfkdqiydifqk
lnsntqvvllsatmpsdvlevtkkfmrdpirilvk