PDB entry 2g77

View 2g77 on RCSB PDB site
Description: Crystal Structure of Gyp1 TBC domain in complex with Rab33 GTPase bound to GDP and AlF3
Class: hydrolase activator/protein transport
Keywords: Protein transport, Gyp1 TBC domain, Rab33, vesicular trafficking
Deposited on 2006-02-27, released 2006-07-25
The last revision prior to the SCOP 1.75 freeze date was dated 2006-07-25, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.26 Å
R-factor: 0.207
AEROSPACI score: 0.43 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: GTPase-activating protein GYP1
    Species: Saccharomyces cerevisiae
    Gene: GYP1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q08484
      • engineered (177)
    Domains in SCOP 1.75: d2g77a1, d2g77a2
  • Chain 'B':
    Compound: Ras-related protein Rab-33B
    Species: MUS MUSCULUS
    Gene: Rab33b
    Database cross-references and differences (RAF-indexed):
    • Uniprot O35963 (Start-197)
      • modified residue (111)
      • modified residue (114)
      • modified residue (167)
      • modified residue (188)
    Domains in SCOP 1.75: d2g77b1
  • Heterogens: MG, GDP, AF3, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2g77A (A:)
mghhhhhhgslvprgsdvqelnsiiqriskfdnilkdktiinqqdlrqiswngipkihrp
vvwklligylpvntkrqegflqrkrkeyrdslkhtfsdqhsrdiptwhqieidiprtnph
iplyqfksvqnslqrilylwairhpasgyvqgindlvtpffetflteylppsqiddvkik
dpstymvdeqitdleadtfwcltklleqitdnyihgqpgilrqvknlsqlvkridadlyn
hfqnehvefiqfafrwmncllmrefqmgtvirmwdtylsetsqevtssysmssndikppv
tpteprvasfvtptkdfqspttalsnmtpnnavedsgkmrqsslnefhvfvcaaflikws
dqlmemdfqetitflqnpptkdwtetdiemllseafiwqslykdatshwl

    Sequence, based on observed residues (ATOM records): (download) 
    >2g77A (A:)
qelnsiiqriskfdnilkdktiinqqdlrqiswngipkihrpvvwklligylpvntkrqe
gflqrkrkeyrdslkhtfsdqhsrdiptwhqieidiprtnphiplyqfksvqnslqrily
lwairhpasgyvqgindlvtpffetflteylppsqiddvkikdpstymvdeqitdleadt
fwcltklleqitdnyihgqpgilrqvknlsqlvkridadlynhfqnehvefiqfafrwmn
cllmrefqmgtvirmwdtylsetsqqsslnefhvfvcaaflikwsdqlmemdfqetitfl
qnpptkdwtetdiemllseafiwqslykdat

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2g77B (B:)
mghhhhhhgssscavsgasgclpparsrifkiivigdsnvgktcltyrfcagrfpdrtea
tigvdfreravdidgerikiqlwdtagqerfrksmvqhyyrnvhavvfvydmtnmasfhs
lpawieeckqhllandiprilvgnkcdlrsaiqvptdlaqkfadthsmplfetsaknpnd
ndhveaifmtlahklksh

    Sequence, based on observed residues (ATOM records): (download) 
    >2g77B (B:)
rsrifkiivigdsnvgktcltyrfcagrfpdrteatigvdfreravdidgerikiqlwdt
agqerfrksmvqhyyrnvhavvfvydmtnmasfhslpawieeckqhllandiprilvgnk
cdlrsaiqvptdlaqkfadthsmplfetsaknpndndhveaifmtlahklksh