PDB entry 2g71

View 2g71 on RCSB PDB site
Description: Structure of hPNMT with inhibitor 3-fluoromethyl-7-trifluoropropyl-THIQ and AdoHcy
Class: transferase
Keywords: methyltransferase, TRANSFERASE
Deposited on 2006-02-27, released 2007-02-13
The last revision prior to the SCOPe 2.05 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.213
AEROSPACI score: 0.39 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Phenylethanolamine N-methyltransferase
    Species: Homo sapiens [TaxId:9606]
    Gene: PNMT
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d2g71a_
  • Chain 'B':
    Compound: Phenylethanolamine N-methyltransferase
    Species: Homo sapiens [TaxId:9606]
    Gene: PNMT
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d2g71b_
  • Heterogens: SAH, FTS, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2g71A (A:)
msgadrspnagaapdsapgqaavasayqrfepraylrnnyapprgdlcnpngvgpwklrc
laqtfatgevsgrtlidigsgptvyqllsacshfeditmtdflevnrqelgrwlqeepga
fnwsmysqhacliegkgecwqdkerqlrarvkrvlpidvhqpqplgagspaplpadalvs
afcleavspdlasfqraldhittllrpgghllligaleeswylagearltvvpvseeevr
ealvrsgykvrdlrtyimpahlqtgvddvkgvffawaqkvglehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2g71A (A:)
aavasayqrfepraylrnnyapprgdlcnpngvgpwklrclaqtfatgevsgrtlidigs
gptvyqllsacshfeditmtdflevnrqelgrwlqeepgafnwsmysqhacliegkgecw
qdkerqlrarvkrvlpidvhqpqplgagspaplpadalvsafcleavspdlasfqraldh
ittllrpgghllligaleeswylagearltvvpvseeevrealvrsgykvrdlrtyimpa
hlqtgvddvkgvffawaqkvg

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2g71B (B:)
msgadrspnagaapdsapgqaavasayqrfepraylrnnyapprgdlcnpngvgpwklrc
laqtfatgevsgrtlidigsgptvyqllsacshfeditmtdflevnrqelgrwlqeepga
fnwsmysqhacliegkgecwqdkerqlrarvkrvlpidvhqpqplgagspaplpadalvs
afcleavspdlasfqraldhittllrpgghllligaleeswylagearltvvpvseeevr
ealvrsgykvrdlrtyimpahlqtgvddvkgvffawaqkvglehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2g71B (B:)
pdsapgqaavasayqrfepraylrnnyapprgdlcnpngvgpwklrclaqtfatgevsgr
tlidigsgptvyqllsacshfeditmtdflevnrqelgrwlqeepgafnwsmysqhacli
egkgecwqdkerqlrarvkrvlpidvhqpqplgagspaplpadalvsafcleavspdlas
fqraldhittllrpgghllligaleeswylagearltvvpvseeevrealvrsgykvrdl
rtyimpahlqtgvddvkgvffawaqkvg