PDB entry 2g70

View 2g70 on RCSB PDB site
Description: Structure of human PNMT in complex with inhibitor 3-hydroxymethyl-7-nitro-THIQ and AdoMet (SAM)
Class: transferase
Keywords: methyltransferase
Deposited on 2006-02-27, released 2007-02-13
The last revision prior to the SCOP 1.73 freeze date was dated 2007-02-13, with a file datestamp of 2007-06-28.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.24
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Phenylethanolamine N-methyltransferase
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d2g70a1
  • Chain 'B':
    Compound: Phenylethanolamine N-methyltransferase
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d2g70b1
  • Heterogens: PO4, SAM, HNT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2g70A (A:)
msgadrspnagaapdsapgqaavasayqrfepraylrnnyapprgdlcnpngvgpwklrc
laqtfatgevsgrtlidigsgptvyqllsacshfeditmtdflevnrqelgrwlqeepga
fnwsmysqhacliegkgecwqdkerqlrarvkrvlpidvhqpqplgagspaplpadalvs
afcleavspdlasfqraldhittllrpgghllligaleeswylagearltvvpvseeevr
ealvrsgykvrdlrtyimpahlqtgvddvkgvffawaqkvglehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2g70A (A:)
qaavasayqrfepraylrnnyapprgdlcnpngvgpwklrclaqtfatgevsgrtlidig
sgptvyqllsacshfeditmtdflevnrqelgrwlqeepgafnwsmysqhacliegkgec
wqdkerqlrarvkrvlpidvhqpqplgagspaplpadalvsafcleavspdlasfqrald
hittllrpgghllligaleeswylagearltvvpvseeevrealvrsgykvrdlrtyimp
ahlqtgvddvkgvffawaqkv

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2g70B (B:)
msgadrspnagaapdsapgqaavasayqrfepraylrnnyapprgdlcnpngvgpwklrc
laqtfatgevsgrtlidigsgptvyqllsacshfeditmtdflevnrqelgrwlqeepga
fnwsmysqhacliegkgecwqdkerqlrarvkrvlpidvhqpqplgagspaplpadalvs
afcleavspdlasfqraldhittllrpgghllligaleeswylagearltvvpvseeevr
ealvrsgykvrdlrtyimpahlqtgvddvkgvffawaqkvglehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2g70B (B:)
sapgqaavasayqrfepraylrnnyapprgdlcnpngvgpwklrclaqtfatgevsgrtl
idigsgptvyqllsacshfeditmtdflevnrqelgrwlqeepgafnwsmysqhaclieg
kgecwqdkerqlrarvkrvlpidvhqpqplgagspaplpadalvsafcleavspdlasfq
raldhittllrpgghllligaleeswylagearltvvpvseeevrealvrsgykvrdlrt
yimpahlqtgvddvkgvffawaqkv