PDB entry 2g5f

View 2g5f on RCSB PDB site
Description: The structure of MbtI from Mycobacterium Tuberculosis, the first enzyme in the synthesis of Mycobactin, reveals it to be a salicylate synthase
Class: biosynthetic protein
Keywords: Beta Sandwhich, Structural Genomics, PSI, Protein Structure Initiative, TB Structural Genomics Consortium, TBSGC, BIOSYNTHETIC PROTEIN
Deposited on 2006-02-22, released 2006-09-05
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.205
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: COG0147: Anthranilate/para-aminobenzoate synthases component I
    Species: Mycobacterium tuberculosis [TaxId:83332]
    Gene: MbtI
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2g5fa1
  • Chain 'B':
    Compound: COG0147: Anthranilate/para-aminobenzoate synthases component I
    Species: Mycobacterium tuberculosis [TaxId:83332]
    Gene: MbtI
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2g5fb_
  • Chain 'C':
    Compound: COG0147: Anthranilate/para-aminobenzoate synthases component I
    Species: Mycobacterium tuberculosis [TaxId:83332]
    Gene: MbtI
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2g5fc_
  • Chain 'D':
    Compound: COG0147: Anthranilate/para-aminobenzoate synthases component I
    Species: Mycobacterium tuberculosis [TaxId:83332]
    Gene: MbtI
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2g5fd_
  • Heterogens: PYR, IMD, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2g5fA (A:)
vselsvatgavstasssipmpagvnpadlaaelaavvtesvdedyllyecdgqwvlaagv
qamveldsdelrvirdgvtrrqqwsgrpgaalgeavdrllletdqafgwvafefgvhryg
lqqrlaphtplarvfsprtrimvsekeirlfdagirhreaidrllatgvrevpqsrsvdv
sddpsgfrrrvavavdeiaagryhkvilsrcvevpfaidfpltyrlgrrhntpvrsfllq
lggiralgyspelvtavradgvviteplagtralgrgpaidrlarddlesnskeivehai
svrssleeitdiaepgsaavidfmtvrergsvqhlgstirarldpssdrmaalealfpav
tasgipkaagveaifrldecprglysgavvmlsadggldaaltlraayqvggrtwlraga
giieeseperefeetceklstltpylvarq

    Sequence, based on observed residues (ATOM records): (download) 
    >2g5fA (A:)
sssipmpagvnpadlaaelaavvtesvdedyllyecdgqwvlaagvqamveldsdelrvi
rdgvtrrqqwsgrpgaalgeavdrllletdqafgwvafefgvhryglqqrlaphtplarv
fsprtrimvsekeirlfdagirhreaidrllatgvrevpqsrsvdvsddpsgfrrrvava
vdeiaagryhkvilsrcvevpfaidfpltyrlgrrhntpvrsfllqlggiralgyspelv
tavradgvviteplagtralgrgpaidrlarddlesnskeivehaisvrssleeitdiae
pgsaavidfmtvrergsvqhlgstirarldpssdrmaalealfpavtasgipkaagveai
frldecprglysgavvmlsadggldaaltlraayqvggrtwlragagiieeseperefee
tceklstltpylvar

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2g5fB (B:)
vselsvatgavstasssipmpagvnpadlaaelaavvtesvdedyllyecdgqwvlaagv
qamveldsdelrvirdgvtrrqqwsgrpgaalgeavdrllletdqafgwvafefgvhryg
lqqrlaphtplarvfsprtrimvsekeirlfdagirhreaidrllatgvrevpqsrsvdv
sddpsgfrrrvavavdeiaagryhkvilsrcvevpfaidfpltyrlgrrhntpvrsfllq
lggiralgyspelvtavradgvviteplagtralgrgpaidrlarddlesnskeivehai
svrssleeitdiaepgsaavidfmtvrergsvqhlgstirarldpssdrmaalealfpav
tasgipkaagveaifrldecprglysgavvmlsadggldaaltlraayqvggrtwlraga
giieeseperefeetceklstltpylvarq

    Sequence, based on observed residues (ATOM records): (download) 
    >2g5fB (B:)
sipmpagvnpadlaaelaavvtededyllyecdgqwvlaagvqamveldsdelrvirgvt
rrqqwsgrpgaalgeavdrllletdqafgwvafefgvhryglqqrlaphtplarvfsprt
rimvsekeirlfdagirhreaidrllatgvrevpqsrsvdvsddpsgfrrrvavavdeia
agryhkvilsrcvevpfaidfpltyrlgrrhntpvrsfllqlggiralgyspelvtavra
dgvviteplagtralgrgpaidrlarddlesnskeivehaisvrssleeitdiaepgsaa
vidfmtvrergsvqhlgstirarldpssdrmaalealfpavtasgipkaagveaifrlde
cprglysgavvmlsadggldaaltlraayqvggrtwlragagiieeseperefeetcekl
stltpylvar

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2g5fC (C:)
vselsvatgavstasssipmpagvnpadlaaelaavvtesvdedyllyecdgqwvlaagv
qamveldsdelrvirdgvtrrqqwsgrpgaalgeavdrllletdqafgwvafefgvhryg
lqqrlaphtplarvfsprtrimvsekeirlfdagirhreaidrllatgvrevpqsrsvdv
sddpsgfrrrvavavdeiaagryhkvilsrcvevpfaidfpltyrlgrrhntpvrsfllq
lggiralgyspelvtavradgvviteplagtralgrgpaidrlarddlesnskeivehai
svrssleeitdiaepgsaavidfmtvrergsvqhlgstirarldpssdrmaalealfpav
tasgipkaagveaifrldecprglysgavvmlsadggldaaltlraayqvggrtwlraga
giieeseperefeetceklstltpylvarq

    Sequence, based on observed residues (ATOM records): (download) 
    >2g5fC (C:)
sssipmpagvnpadlaaelaavvtesvdedyllyecdgqwvlaagvqamveldsdelrvi
rdgvtrrqqwsgrpgaalgeavdrllletdqafgwvafefgvhryglqqrlaphtplarv
fsprtrimvsekeirlfdagirhreaidrllatgvrevpqsrsvdvsddpsgfrrrvava
vdeiaagryhkvilsrcvevpfaidfpltyrlgrrhntpvrsfllqlggiralgyspelv
tavradgvviteplagtralgrgpaidrlarddlesnskeivehaisvrssleeitdiae
pgsaavidfmtvrergsvqhlgstirarldpssdrmaalealfpavtasgipkaagveai
frldecprglysgavvmlsadggldaaltlraayqvggrtwlragagiieeseperefee
tceklstltpylvar

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2g5fD (D:)
vselsvatgavstasssipmpagvnpadlaaelaavvtesvdedyllyecdgqwvlaagv
qamveldsdelrvirdgvtrrqqwsgrpgaalgeavdrllletdqafgwvafefgvhryg
lqqrlaphtplarvfsprtrimvsekeirlfdagirhreaidrllatgvrevpqsrsvdv
sddpsgfrrrvavavdeiaagryhkvilsrcvevpfaidfpltyrlgrrhntpvrsfllq
lggiralgyspelvtavradgvviteplagtralgrgpaidrlarddlesnskeivehai
svrssleeitdiaepgsaavidfmtvrergsvqhlgstirarldpssdrmaalealfpav
tasgipkaagveaifrldecprglysgavvmlsadggldaaltlraayqvggrtwlraga
giieeseperefeetceklstltpylvarq

    Sequence, based on observed residues (ATOM records): (download) 
    >2g5fD (D:)
sssipmpagvnpadlaaelaavvtesvdedyllyecdgqwvlaagvqamveldsdelrvi
rdgvtrrqqwsgrpgaalgeavdrllletdqafgwvafefgvhryglqqrlaphtplarv
fsprtrimvsekeirlfdagirhreaidrllatgvrevpqsrsvdvsddpsgfrrrvava
vdeiaagryhkvilsrcvevpfaidfpltyrlgrrhntpvrsfllqlggiralgyspelv
tavradgvviteplagtralgrgpaidrlarddlesnskeivehaisvrssleeitdiae
pgsaavidfmtvrergsvqhlgstirarldpssdrmaalealfpavtasgipkaagveai
frldecprglysgavvmlsadggldaaltlraayqvggrtwlragagiieeseperefee
tceklstltpylvar