PDB entry 2g59

View 2g59 on RCSB PDB site
Description: Crystal Structure of the Catalytic Domain of Protein Tyrosine Phosphatase from Homo sapiens
Class: hydrolase
Keywords: Protein Tyrosine Phosphatase, Dephosphorylation, Structural Genomics, PSI, Protein Structure Initiative, New York SGX Research Center for Structural Genomics, NYSGXRC, HYDROLASE
Deposited on 2006-02-22, released 2006-03-14
The last revision prior to the SCOPe 2.04 freeze date was dated 2008-03-25, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.19 Å
R-factor: 0.199
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Receptor-type tyrosine-protein phosphatase O
    Species: Homo sapiens [TaxId:9606]
    Gene: PTPRO, GLEPP1, PTPU2
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q16827 (2-288)
      • expression tag (1)
      • expression tag (289-290)
    Domains in SCOPe 2.04: d2g59a_
  • Chain 'B':
    Compound: Receptor-type tyrosine-protein phosphatase O
    Species: Homo sapiens [TaxId:9606]
    Gene: PTPRO, GLEPP1, PTPU2
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q16827 (2-288)
      • expression tag (1)
      • expression tag (289-295)
    Domains in SCOPe 2.04: d2g59b_
  • Heterogens: PO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2g59A (A:)
msltnpvqlddfdayikdmakdsdykfslqfeelkligldiphfaadlplnrcknrytni
lpydfsrvrlvsmneeegadyinanyipgynspqeyiatqgplpetrndfwkmvlqqksq
iivmltqcnekrrvkcdhywpfteepiaygditvemiseeeqddwacrhfrinyademqd
vmhfnytawpdhgvptanaaesilqfvhmvrqqatkskgpmiihcsagvgrtgtfialdr
llqhirdhefvdilglvsemrsyrmsmvqteeqyifihqcvqlmwmkkkeghhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2g59A (A:)
sltnpvqlddfdayikdmakdsdykfslqfeelkligldiphfaadlplnrcknrytnil
pydfsrvrlvsmneeegadyinanyipgynspqeyiatqgplpetrndfwkmvlqqksqi
ivmltqcnekrrvkcdhywpfteepiaygditvemiseeeqddwacrhfrinyademqdv
mhfnytawpdhgvptaesilqfvhmvrqqatkskgpmiihcsagvgrtgtfialdrllqh
irdhefvdilglvsemrsyrmsmvqteeqyifihqcvqlmwmkkkeg

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2g59B (B:)
msltnpvqlddfdayikdmakdsdykfslqfeelkligldiphfaadlplnrcknrytni
lpydfsrvrlvsmneeegadyinanyipgynspqeyiatqgplpetrndfwkmvlqqksq
iivmltqcnekrrvkcdhywpfteepiaygditvemiseeeqddwacrhfrinyademqd
vmhfnytawpdhgvptanaaesilqfvhmvrqqatkskgpmiihcsagvgrtgtfialdr
llqhirdhefvdilglvsemrsyrmsmvqteeqyifihqcvqlmwmkkkeghhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2g59B (B:)
sltnpvqlddfdayikdmakdsdykfslqfeelkligldiphfaadlplnrcknrytnil
pydfsrvrlveegadyinanyipgynspqeyiatqgplpetrndfwkmvlqqksqiivml
tqdhywpfteepiaygditvemiseeeqddwacrhfrinyademqdvmhfnytawpdhgv
ptanaaesilqfvhmvrqqatkskgpmiihcsagvgrtgtfialdrllqhirdhefvdil
glvsemrsyrmsmvqteeqyifihqcvqlmwmkkkeghhhhh