PDB entry 2g4c

View 2g4c on RCSB PDB site
Description: Crystal Structure of human DNA polymerase gamma accessory subunit
Class: transferase
Keywords: alpha and beta protein, anti-codon binding domain-like, aaRS class II-like, TRANSFERASE
Deposited on 2006-02-22, released 2006-04-18
The last revision prior to the SCOPe 2.02 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 3.15 Å
R-factor: 0.232
AEROSPACI score: 0.15 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA polymerase gamma subunit 2
    Species: Homo sapiens [TaxId:9606]
    Gene: POLG2, MTPOLB
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UHN1 (Start-473)
      • see remark 999 (157)
    Domains in SCOPe 2.02: d2g4ca1, d2g4ca2
  • Chain 'B':
    Compound: DNA polymerase gamma subunit 2
    Species: Homo sapiens [TaxId:9606]
    Gene: POLG2, MTPOLB
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UHN1 (Start-473)
      • see remark 999 (157)
    Domains in SCOPe 2.02: d2g4cb1, d2g4cb2
  • Chain 'C':
    Compound: DNA polymerase gamma subunit 2
    Species: Homo sapiens [TaxId:9606]
    Gene: POLG2, MTPOLB
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UHN1 (Start-473)
      • see remark 999 (157)
    Domains in SCOPe 2.02: d2g4cc1, d2g4cc2
  • Chain 'D':
    Compound: DNA polymerase gamma subunit 2
    Species: Homo sapiens [TaxId:9606]
    Gene: POLG2, MTPOLB
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UHN1 (Start-473)
      • see remark 999 (157)
    Domains in SCOPe 2.02: d2g4cd1, d2g4cd2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2g4cA (A:)
mrgshhhhhhgstmdagqpelltersspkgghvkshaelegngehpeapgsgegsealle
icqrrhflsgskqqlsrdsllsgchpgfgplgvelrknlaaewwtsvvvfreqvfpvdal
hhkpgpllpgdsafrlvsaetlreilqdkelskeqlvtflenvlktsgklrenllhgale
hyvncldlvnkrlpyglaqigvcfhpvfdtkqirngvksigekteaslvwftpprtsnqw
ldfwlrhrlqwwrkfamspsnfsssdcqdeegrkgnklyynfpwgkelietlwnlgdhel
lhmypgnvsklhgrdgrknvvpcvlsvngdldrgmlaylydsfqltensftrkknlhrkv
lklhpclapikvaldvgrgptlelrqvcqglfnellengisvwpgyletmqssleqlysk
ydemsilftvlvtettlenglihlrsrdttmkemmhisklkdflikyissaknv

    Sequence, based on observed residues (ATOM records): (download) 
    >2g4cA (A:)
sealleicqrrhflsgskqqlsrdsllsgchpgfgplgvelrknlaaewwtsvvvfreqv
fpvdalhhkpgpllpgdsafrlvsaetlreilqdkelskeqlvtflenvlktsgklrenl
lhgalehyvncldlvnkrlpyglaqigvcfhpvksigekteaslvwftpprtsnqwldfw
lrhrlqwwrkfamspsnfsssdcqdeegrkgnklyynfpwgkelietlwnlgdhellhmy
pgnvsklhgrdgrknvvpcvlsvngdldrgmlaylydsfqrkvlklhpclapikvaldvg
rgptlelrqvcqglfnellengisvwpgyletmqssleqlyskydemsilftvlvtettl
englihlrsrdttmkemmhisklkdflikyissaknv

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2g4cB (B:)
mrgshhhhhhgstmdagqpelltersspkgghvkshaelegngehpeapgsgegsealle
icqrrhflsgskqqlsrdsllsgchpgfgplgvelrknlaaewwtsvvvfreqvfpvdal
hhkpgpllpgdsafrlvsaetlreilqdkelskeqlvtflenvlktsgklrenllhgale
hyvncldlvnkrlpyglaqigvcfhpvfdtkqirngvksigekteaslvwftpprtsnqw
ldfwlrhrlqwwrkfamspsnfsssdcqdeegrkgnklyynfpwgkelietlwnlgdhel
lhmypgnvsklhgrdgrknvvpcvlsvngdldrgmlaylydsfqltensftrkknlhrkv
lklhpclapikvaldvgrgptlelrqvcqglfnellengisvwpgyletmqssleqlysk
ydemsilftvlvtettlenglihlrsrdttmkemmhisklkdflikyissaknv

    Sequence, based on observed residues (ATOM records): (download) 
    >2g4cB (B:)
sealleicqrrhflsgskqqlsrdsllsgchpgfgplgvelrknlaaewwtsvvvfreqv
fpvdalhhkpgpllpgdsafrlvsaetlreilqdkelskeqlvtflenvlktsgklrenl
lhgalehyvncldlvnkrlpyglaqigvcfhpvksigekteaslvwftpprtsnqwldfw
lrhrlqwwrkfamspsnfsssdcqdeegrkgnklyynfpwgkelietlwnlgdhellhmy
pgnvsklhgrdgrknvvpcvlsvngdldrgmlaylydsfqrkvlklhpclapikvaldvg
rgptlelrqvcqglfnellengisvwpgyletmqssleqlyskydemsilftvlvtettl
englihlrsrdttmkemmhisklkdflikyissaknv

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2g4cC (C:)
mrgshhhhhhgstmdagqpelltersspkgghvkshaelegngehpeapgsgegsealle
icqrrhflsgskqqlsrdsllsgchpgfgplgvelrknlaaewwtsvvvfreqvfpvdal
hhkpgpllpgdsafrlvsaetlreilqdkelskeqlvtflenvlktsgklrenllhgale
hyvncldlvnkrlpyglaqigvcfhpvfdtkqirngvksigekteaslvwftpprtsnqw
ldfwlrhrlqwwrkfamspsnfsssdcqdeegrkgnklyynfpwgkelietlwnlgdhel
lhmypgnvsklhgrdgrknvvpcvlsvngdldrgmlaylydsfqltensftrkknlhrkv
lklhpclapikvaldvgrgptlelrqvcqglfnellengisvwpgyletmqssleqlysk
ydemsilftvlvtettlenglihlrsrdttmkemmhisklkdflikyissaknv

    Sequence, based on observed residues (ATOM records): (download) 
    >2g4cC (C:)
ealleicqrrhflsgskqqlsrdsllsgchpgfgplgvelrknlaaewwtsvvvfreqvf
pvdalhhkpgpllpgdsafrlvsaetlreilqdkelskeqlvtflenvlktsgklrenll
hgalehyvncldlvnkrlpyglaqigvcfhpvksigekteaslvwftpprtsnqwldfwl
rhrlqwwrkfamspsnfsssdcqdeegrkgnklyynfpwgkelietlwnlgdhellhmyp
gnvsklhgrdgrknvvpcvlsvngdldrgmlaylydsfqhrkvlklhpclapikvaldvg
rgptlelrqvcqglfnellengisvwpgyletmqssleqlyskydemsilftvlvtettl
englihlrsrdttmkemmhisklkdflikyissaknv

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2g4cD (D:)
mrgshhhhhhgstmdagqpelltersspkgghvkshaelegngehpeapgsgegsealle
icqrrhflsgskqqlsrdsllsgchpgfgplgvelrknlaaewwtsvvvfreqvfpvdal
hhkpgpllpgdsafrlvsaetlreilqdkelskeqlvtflenvlktsgklrenllhgale
hyvncldlvnkrlpyglaqigvcfhpvfdtkqirngvksigekteaslvwftpprtsnqw
ldfwlrhrlqwwrkfamspsnfsssdcqdeegrkgnklyynfpwgkelietlwnlgdhel
lhmypgnvsklhgrdgrknvvpcvlsvngdldrgmlaylydsfqltensftrkknlhrkv
lklhpclapikvaldvgrgptlelrqvcqglfnellengisvwpgyletmqssleqlysk
ydemsilftvlvtettlenglihlrsrdttmkemmhisklkdflikyissaknv

    Sequence, based on observed residues (ATOM records): (download) 
    >2g4cD (D:)
ealleicqrrhflsgskqqlsrdsllsgchpgfgplgvelrknlaaewwtsvvvfreqvf
pvdalhhkpgpllpgdsafrlvsaetlreilqdkelskeqlvtflenvlktsgklrenll
hgalehyvncldlvnkrlpyglaqigvcfhpvksigekteaslvwftpprtsnqwldfwl
rhrlqwwrkfamspsnfsssdcqdeegrkgnklyynfpwgkelietlwnlgdhellhmyp
gnvsklhgrdgrknvvpcvlsvngdldrgmlaylydsfqhrkvlklhpclapikvaldvg
rgptlelrqvcqglfnellengisvwpgyletmqssleqlyskydemsilftvlvtettl
englihlrsrdttmkemmhisklkdflikyissaknv