PDB entry 2g4c

View 2g4c on RCSB PDB site
Description: Crystal Structure of human DNA polymerase gamma accessory subunit
Class: transferase
Keywords: alpha and beta protein, anti-codon binding domain-like, aaRS class II-like
Deposited on 2006-02-22, released 2006-04-18
The last revision prior to the SCOP 1.73 freeze date was dated 2006-05-09, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 3.15 Å
R-factor: 0.232
AEROSPACI score: 0.15 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA polymerase gamma subunit 2
    Species: HOMO SAPIENS
    Gene: POLG2, MTPOLB
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UHN1 (Start-473)
      • see remark 999 (157)
    Domains in SCOP 1.73: d2g4ca1, d2g4ca2
  • Chain 'B':
    Compound: DNA polymerase gamma subunit 2
    Species: HOMO SAPIENS
    Gene: POLG2, MTPOLB
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UHN1 (Start-473)
      • see remark 999 (157)
    Domains in SCOP 1.73: d2g4cb1, d2g4cb2
  • Chain 'C':
    Compound: DNA polymerase gamma subunit 2
    Species: HOMO SAPIENS
    Gene: POLG2, MTPOLB
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UHN1 (Start-473)
      • see remark 999 (157)
    Domains in SCOP 1.73: d2g4cc1, d2g4cc2
  • Chain 'D':
    Compound: DNA polymerase gamma subunit 2
    Species: HOMO SAPIENS
    Gene: POLG2, MTPOLB
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UHN1 (Start-473)
      • see remark 999 (157)
    Domains in SCOP 1.73: d2g4cd1, d2g4cd2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2g4cA (A:)
    mrgshhhhhhgstmdagqpelltersspkgghvkshaelegngehpeapgsgegsealle
    icqrrhflsgskqqlsrdsllsgchpgfgplgvelrknlaaewwtsvvvfreqvfpvdal
    hhkpgpllpgdsafrlvsaetlreilqdkelskeqlvtflenvlktsgklrenllhgale
    hyvncldlvnkrlpyglaqigvcfhpvfdtkqirngvksigekteaslvwftpprtsnqw
    ldfwlrhrlqwwrkfamspsnfsssdcqdeegrkgnklyynfpwgkelietlwnlgdhel
    lhmypgnvsklhgrdgrknvvpcvlsvngdldrgmlaylydsfqltensftrkknlhrkv
    lklhpclapikvaldvgrgptlelrqvcqglfnellengisvwpgyletmqssleqlysk
    ydemsilftvlvtettlenglihlrsrdttmkemmhisklkdflikyissaknv
    

    Sequence, based on observed residues (ATOM records): (download)
    >2g4cA (A:)
    sealleicqrrhflsgskqqlsrdsllsgchpgfgplgvelrknlaaewwtsvvvfreqv
    fpvdalhhkpgpllpgdsafrlvsaetlreilqdkelskeqlvtflenvlktsgklrenl
    lhgalehyvncldlvnkrlpyglaqigvcfhpvksigekteaslvwftpprtsnqwldfw
    lrhrlqwwrkfamspsnfsssdcqdeegrkgnklyynfpwgkelietlwnlgdhellhmy
    pgnvsklhgrdgrknvvpcvlsvngdldrgmlaylydsfqrkvlklhpclapikvaldvg
    rgptlelrqvcqglfnellengisvwpgyletmqssleqlyskydemsilftvlvtettl
    englihlrsrdttmkemmhisklkdflikyissaknv
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >2g4cB (B:)
    mrgshhhhhhgstmdagqpelltersspkgghvkshaelegngehpeapgsgegsealle
    icqrrhflsgskqqlsrdsllsgchpgfgplgvelrknlaaewwtsvvvfreqvfpvdal
    hhkpgpllpgdsafrlvsaetlreilqdkelskeqlvtflenvlktsgklrenllhgale
    hyvncldlvnkrlpyglaqigvcfhpvfdtkqirngvksigekteaslvwftpprtsnqw
    ldfwlrhrlqwwrkfamspsnfsssdcqdeegrkgnklyynfpwgkelietlwnlgdhel
    lhmypgnvsklhgrdgrknvvpcvlsvngdldrgmlaylydsfqltensftrkknlhrkv
    lklhpclapikvaldvgrgptlelrqvcqglfnellengisvwpgyletmqssleqlysk
    ydemsilftvlvtettlenglihlrsrdttmkemmhisklkdflikyissaknv
    

    Sequence, based on observed residues (ATOM records): (download)
    >2g4cB (B:)
    sealleicqrrhflsgskqqlsrdsllsgchpgfgplgvelrknlaaewwtsvvvfreqv
    fpvdalhhkpgpllpgdsafrlvsaetlreilqdkelskeqlvtflenvlktsgklrenl
    lhgalehyvncldlvnkrlpyglaqigvcfhpvksigekteaslvwftpprtsnqwldfw
    lrhrlqwwrkfamspsnfsssdcqdeegrkgnklyynfpwgkelietlwnlgdhellhmy
    pgnvsklhgrdgrknvvpcvlsvngdldrgmlaylydsfqrkvlklhpclapikvaldvg
    rgptlelrqvcqglfnellengisvwpgyletmqssleqlyskydemsilftvlvtettl
    englihlrsrdttmkemmhisklkdflikyissaknv
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >2g4cC (C:)
    mrgshhhhhhgstmdagqpelltersspkgghvkshaelegngehpeapgsgegsealle
    icqrrhflsgskqqlsrdsllsgchpgfgplgvelrknlaaewwtsvvvfreqvfpvdal
    hhkpgpllpgdsafrlvsaetlreilqdkelskeqlvtflenvlktsgklrenllhgale
    hyvncldlvnkrlpyglaqigvcfhpvfdtkqirngvksigekteaslvwftpprtsnqw
    ldfwlrhrlqwwrkfamspsnfsssdcqdeegrkgnklyynfpwgkelietlwnlgdhel
    lhmypgnvsklhgrdgrknvvpcvlsvngdldrgmlaylydsfqltensftrkknlhrkv
    lklhpclapikvaldvgrgptlelrqvcqglfnellengisvwpgyletmqssleqlysk
    ydemsilftvlvtettlenglihlrsrdttmkemmhisklkdflikyissaknv
    

    Sequence, based on observed residues (ATOM records): (download)
    >2g4cC (C:)
    ealleicqrrhflsgskqqlsrdsllsgchpgfgplgvelrknlaaewwtsvvvfreqvf
    pvdalhhkpgpllpgdsafrlvsaetlreilqdkelskeqlvtflenvlktsgklrenll
    hgalehyvncldlvnkrlpyglaqigvcfhpvksigekteaslvwftpprtsnqwldfwl
    rhrlqwwrkfamspsnfsssdcqdeegrkgnklyynfpwgkelietlwnlgdhellhmyp
    gnvsklhgrdgrknvvpcvlsvngdldrgmlaylydsfqhrkvlklhpclapikvaldvg
    rgptlelrqvcqglfnellengisvwpgyletmqssleqlyskydemsilftvlvtettl
    englihlrsrdttmkemmhisklkdflikyissaknv
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >2g4cD (D:)
    mrgshhhhhhgstmdagqpelltersspkgghvkshaelegngehpeapgsgegsealle
    icqrrhflsgskqqlsrdsllsgchpgfgplgvelrknlaaewwtsvvvfreqvfpvdal
    hhkpgpllpgdsafrlvsaetlreilqdkelskeqlvtflenvlktsgklrenllhgale
    hyvncldlvnkrlpyglaqigvcfhpvfdtkqirngvksigekteaslvwftpprtsnqw
    ldfwlrhrlqwwrkfamspsnfsssdcqdeegrkgnklyynfpwgkelietlwnlgdhel
    lhmypgnvsklhgrdgrknvvpcvlsvngdldrgmlaylydsfqltensftrkknlhrkv
    lklhpclapikvaldvgrgptlelrqvcqglfnellengisvwpgyletmqssleqlysk
    ydemsilftvlvtettlenglihlrsrdttmkemmhisklkdflikyissaknv
    

    Sequence, based on observed residues (ATOM records): (download)
    >2g4cD (D:)
    ealleicqrrhflsgskqqlsrdsllsgchpgfgplgvelrknlaaewwtsvvvfreqvf
    pvdalhhkpgpllpgdsafrlvsaetlreilqdkelskeqlvtflenvlktsgklrenll
    hgalehyvncldlvnkrlpyglaqigvcfhpvksigekteaslvwftpprtsnqwldfwl
    rhrlqwwrkfamspsnfsssdcqdeegrkgnklyynfpwgkelietlwnlgdhellhmyp
    gnvsklhgrdgrknvvpcvlsvngdldrgmlaylydsfqhrkvlklhpclapikvaldvg
    rgptlelrqvcqglfnellengisvwpgyletmqssleqlyskydemsilftvlvtettl
    englihlrsrdttmkemmhisklkdflikyissaknv