PDB entry 2g0a

View 2g0a on RCSB PDB site
Description: X-ray structure of mouse pyrimidine 5'-nucleotidase type 1 with lead(II) bound in active site
Class: hydrolase
Keywords: UniProt Q9D020, UMPH-1, Cytosolic 5'-nucleotidase III, Pyrimidine 5'-nucleotidase 1, P5n-1, NT5C3 PROTEIN, AAH38029, BC038029, MM.158936, Lead Poisoning, STRUCTURAL GENOMICS FUNCTIONAL FOLLOW-UP STUDY, PROTEIN STRUCTURE INITIATIVE, PSI, CENTER FOR EUKARYOTIC STRUCTURAL GENOMICS, CESG, HYDROLASE
Deposited on 2006-02-11, released 2006-04-04
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.35 Å
R-factor: 0.153
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cytosolic 5'-nucleotidase III
    Species: Mus musculus [TaxId:10090]
    Gene: Nt5c3
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9D020 (Start-296)
      • modified residue (11-12)
      • modified residue (51)
      • modified residue (109)
      • modified residue (140)
      • modified residue (191)
      • modified residue (244)
      • modified residue (272)
    Domains in SCOPe 2.08: d2g0aa_
  • Chain 'B':
    Compound: Cytosolic 5'-nucleotidase III
    Species: Mus musculus [TaxId:10090]
    Gene: Nt5c3
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9D020 (Start-296)
      • modified residue (11-12)
      • modified residue (51)
      • modified residue (109)
      • modified residue (140)
      • modified residue (191)
      • modified residue (244)
      • modified residue (272)
    Domains in SCOPe 2.08: d2g0ab_
  • Heterogens: PB, EPE, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2g0aA (A:)
stnqesavhlkmmpefqkssvriknptrveeiicglikggaaklqiitdfdmtlsrfsyn
gkrcptchniidncklvtdecrrkllqlkeqyyaievdpvltveekfpymvewytkshgl
lieqgipkaklkeivadsdvmlkegyenffgklqqhgipvfifsagigdvleevirqagv
yhsnvkvvsnfmdfdengvlkgfkgelihvfnkhdgalkntdyfsqlkdnsniillgdsq
gdlrmadgvanvehilkigylndrvdellekymdsydivlvkeeslevvnsilqktl

    Sequence, based on observed residues (ATOM records): (download) 
    >2g0aA (A:)
avhlkmmpefqkssvriknptrveeiicglikggaaklqiitdfdmtlsrfsyngkrcpt
chniidncklvtdecrrkllqlkeqyyaievdpvltveekfpymvewytkshgllieqgi
pkaklkeivadsdvmlkegyenffgklqqhgipvfifsagigdvleevirqagvyhsnvk
vvsnfmdfdengvlkgfkgelihvfnkhdgalkntdyfsqlkdnsniillgdsqgdlrma
dgvanvehilkigylndrvdellekymdsydivlvkeeslevvnsilqktl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2g0aB (B:)
stnqesavhlkmmpefqkssvriknptrveeiicglikggaaklqiitdfdmtlsrfsyn
gkrcptchniidncklvtdecrrkllqlkeqyyaievdpvltveekfpymvewytkshgl
lieqgipkaklkeivadsdvmlkegyenffgklqqhgipvfifsagigdvleevirqagv
yhsnvkvvsnfmdfdengvlkgfkgelihvfnkhdgalkntdyfsqlkdnsniillgdsq
gdlrmadgvanvehilkigylndrvdellekymdsydivlvkeeslevvnsilqktl

    Sequence, based on observed residues (ATOM records): (download) 
    >2g0aB (B:)
avhlkmmpefqkssvriknptrveeiicglikggaaklqiitdfdmtlsrfsyngkrcpt
chniidncklvtdecrrkllqlkeqyyaievdpvltveekfpymvewytkshgllieqgi
pkaklkeivadsdvmlkegyenffgklqqhgipvfifsagigdvleevirqagvyhsnvk
vvsnfmdfdengvlkgfkgelihvfnkhdgalkntdyfsqlkdnsniillgdsqgdlrma
dgvanvehilkigylndrvdellekymdsydivlvkeeslevvnsilqktl