PDB entry 2fyu

View 2fyu on RCSB PDB site
Description: Crystal structure of bovine heart mitochondrial bc1 with jg144 inhibitor
Class: oxidoreductase
Keywords: Transmembrane helices, 11 protein complex, OXIDOREDUCTASE
Deposited on 2006-02-08, released 2006-08-29
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.26 Å
R-factor: 0.249
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ubiquinol-cytochrome-c reductase complex core protein I, mitochondrial
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2fyua1, d2fyua2
  • Chain 'B':
    Compound: Ubiquinol-cytochrome-c reductase complex core protein 2, mitochondrial
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2fyub1, d2fyub2
  • Chain 'C':
    Compound: cytochrome b
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2fyuc1, d2fyuc2
  • Chain 'D':
    Compound: Cytochrome c1, heme protein, mitochondrial
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2fyud1, d2fyud2
  • Chain 'E':
    Compound: Ubiquinol-cytochrome c reductase iron-sulfur subunit, mitochondrial
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2fyue1, d2fyue2
  • Chain 'F':
    Compound: Hypothetical protein LOC616871
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2fyuf_
  • Chain 'G':
    Compound: ubiquinol-cytochrome c reductase complex ubiquinone-binding protein qp-c
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2fyug_
  • Chain 'H':
    Compound: Ubiquinol-cytochrome c reductase complex 11 kDa protein
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2fyuh_
  • Chain 'I':
    Compound: Ubiquinol-cytochrome c reductase iron-sulfur subunit, mitochondrial
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2fyui_
  • Chain 'J':
    Compound: Ubiquinol-cytochrome c reductase complex 7.2 kDa protein
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2fyuj_
  • Chain 'K':
    Compound: Ubiquinol-cytochrome c reductase complex 6.4 kDa protein
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2fyuk_
  • Heterogens: HEM, FDN, FES, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2fyuA (A:)
tatyaqalqsvpetqvsqldnglrvaseqssqptctvgvwidagsryeseknngagyfve
hlafkgtknrpgnalekevesmgahlnaystrehtayyikalskdlpkavelladivqnc
sledsqiekerdvilqelqendtsmrdvvfnylhatafqgtplaqsvegpsenvrklsra
dlteylsrhykaprmvlaaagglehrqlldlaqkhfsglsgtydedavptlspcrftgsq
ichredglplahvaiavegpgwahpdnvalqvanaiighydctygggahlssplasiaat
nklcqsfqtfnicyadtgllgahfvcdhmsiddmmfvlqgqwmrlctsatesevlrgknl
lrnalvshldgttpvcedigrslltygrriplaewesriaevdarvvrevcskyfydqcp
avagfgpieqlpdynrirsgmfwlrf

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2fyuB (B:)
slkvapkvkateapagvpphpqdleftrlpnglviaslenyapasriglfikagsryens
nnlgtshllrlasslttkgassfkitrgieavggklsvtstrenmaytveclrddvdilm
efllnvttapefrrwevaalqpqlridkavalqnpqahvienlhaaayrnalanslycpd
yrigkvtpvelhdyvqnhftsarmaliglgvshpvlkqvaeqflnirgglglsgakakyh
ggeireqngdslvhaalvaesaaigsaeanafsvlqhvlgagphvkrgsnatsslyqava
kgvhqpfdvsafnasysdsglfgfytisqaasagdvikaaynqvktiaqgnlsnpdvqaa
knklkagylmsvessegfldevgsqalaagsytppstvlqqidavadadvinaakkfvsg
rksmaasgnlghtpfidel

    Sequence, based on observed residues (ATOM records): (download) 
    >2fyuB (B:)
vpphpqdleftrlpnglviaslenyapasriglfikagsryensnnlgtshllrlasslt
tkgassfkitrgieavggklsvtstrenmaytveclrddvdilmefllnvttapefrrwe
vaalqpqlridkavalqnpqahvienlhaaayrnalanslycpdyrigkvtpvelhdyvq
nhftsarmaliglgvshpvlkqvaeqflnirgglglsgakakyhggeireqngdslvhaa
lvaesaaigsaeanafsvlqhvlgagphvkrgsnatsslyqavakgvhqpfdvsafnasy
sdsglfgfytisqaasagdvikaaynqvktiaqgnlsnpdvqaaknklkagylmsvesse
gfldevgsqalaagsytppstvlqqidavadadvinaakkfvsgrksmaasgnlghtpfi
del

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2fyuC (C:)
mtnirkshplmkivnnafidlpapsnisswwnfgsllgiclilqiltglflamhytsdtt
tafssvthicrdvnygwiirymhangasmfficlymhvgrglyygsytfletwnigvill
ltvmatafmgyvlpwgqmsfwgatvitnllsaipyigtnlvewiwggfsvdkatltrffa
fhfilpfiimaiamvhllflhetgsnnptgissdvdkipfhpyytikdilgalllilalm
llvlfapdllgdpdnytpanplntpphikpewyflfayailrsipnklggvlalafsili
lalipllhtskqrsmmfrplsqclfwalvadlltltwiggqpvehpyitigqlasvlyfl
lilvlmptagtienkllkw

    Sequence, based on observed residues (ATOM records): (download) 
    >2fyuC (C:)
tnirkshplmkivnnafidlpapsnisswwnfgsllgiclilqiltglflamhytsdttt
afssvthicrdvnygwiirymhangasmfficlymhvgrglyygsytfletwnigvilll
tvmatafmgyvlpwgqmsfwgatvitnllsaipyigtnlvewiwggfsvdkatltrffaf
hfilpfiimaiamvhllflhetgsnnptgissdvdkipfhpyytikdilgalllilalml
lvlfapdllgdpdnytpanplntpphikpewyflfayailrsipnklggvlalafsilil
alipllhtskqrsmmfrplsqclfwalvadlltltwiggqpvehpyitigqlasvlyfll
ilvlmptagtienkllkw

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2fyuD (D:)
sdlelhppsypwshrgllssldhtsirrgfqvykqvcsschsmdyvayrhlvgvcytede
akalaeevevqdgpnedgemfmrpgklsdyfpkpypnpeaaraanngalppdlsyivrar
hggedyvfslltgycepptgvslreglyfnpyfpgqaigmappiynevlefddgtpatms
qvakdvctflrwaaepehdhrkrmglkmllmmglllplvyamkrhkwsvlksrklayrpp
k

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2fyuE (E:)
shtdikvpdfsdyrrpevldstksskessearkgfsylvtatttvgvayaaknvvsqfvs
smsasadvlamskieiklsdipegknmafkwrgkplfvrhrtkkeidqeaavevsqlrdp
qhdlervkkpewviligvcthlgcvpianagdfggyycpchgshydasgrirkgpaplnl
evpsyeftsddmvivg

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >2fyuF (F:)
agrpavsassrwlegirkwyynaagfnklglmrddtihenddvkeairrlpenlyddrvf
rikraldlsmrqqilpkeqwtkyeedksylepylkevirerkereewakk

    Sequence, based on observed residues (ATOM records): (download) 
    >2fyuF (F:)
avsassrwlegirkwyynaagfnklglmrddtihenddvkeairrlpenlyddrvfrikr
aldlsmrqqilpkeqwtkyeedksylepylkevirerkereewakk

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >2fyuG (G:)
grqfghltrvrhvityslspfeqrafphyfskgipnvlrrtracilrvappfvafylvyt
wgtqefekskrknpaayendr

    Sequence, based on observed residues (ATOM records): (download) 
    >2fyuG (G:)
grqfghltrvrhvityslspfeqrafphyfskgipnvlrrtracilrvappfvafylvyt
wgtqefekskrknpa

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >2fyuH (H:)
gdpkeeeeeeeelvdplttvreqceqlekcvkarerlelcdervssrsqteedcteelld
flhardhcvahklfnslk

    Sequence, based on observed residues (ATOM records): (download) 
    >2fyuH (H:)
dplttvreqceqlekcvkarerlelcdervssrsqteedcteelldflhardhcvahklf
nslk

  • Chain 'I':
    Sequence, based on SEQRES records: (download) 
    >2fyuI (I:)
mlsvaarsgpfapvlsatsrgvagalrplvqaavpatsespvldlkrsvlcreslrgqaa
grplvasvslnvpasvry

    Sequence, based on observed residues (ATOM records): (download) 
    >2fyuI (I:)
mlsvaarsgpfapvlsatsrgvagalrplvqaavpatsespvldlkrsvlcreslrg

  • Chain 'J':
    Sequence, based on SEQRES records: (download) 
    >2fyuJ (J:)
vaptltarlysllfrrtstfaltivvgalfferafdqgadaiyehinegklwkhikhkye
nk

    Sequence, based on observed residues (ATOM records): (download) 
    >2fyuJ (J:)
aptltarlysllfrrtstfaltivvgalfferafdqgadaiyehinegklwkhikhkyen

  • Chain 'K':
    Sequence, based on SEQRES records: (download) 
    >2fyuK (K:)
mltrflgpryrqlarnwvptaslwgavgavglvwatdwrlildwvpyingkfkkdd

    Sequence, based on observed residues (ATOM records): (download) 
    >2fyuK (K:)
mltrflgpryrqlarnwvptaslwgavgavglvwatdwrlildwvpyingkfk