PDB entry 2fxo

View 2fxo on RCSB PDB site
Description: Structure of the human beta-myosin S2 fragment
Class: contractile protein
Keywords: coiled coil (dimeric, parallel), familial hypertrophic cardiomyopathy, fhc-associated mutant e924k, thick filament, contractile protein
Deposited on 2006-02-06, released 2006-11-21
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-10-18, with a file datestamp of 2017-10-13.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: N/A
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Myosin heavy chain, cardiac muscle beta isoform
    Species: Homo sapiens [TaxId:9606]
    Gene: HSBMHC
    Database cross-references and differences (RAF-indexed):
    • Uniprot P12883 (3-128)
      • cloning artifact (0-2)
      • engineered (89)
    Domains in SCOPe 2.08: d2fxoa1, d2fxoa2
  • Chain 'B':
    Compound: Myosin heavy chain, cardiac muscle beta isoform
    Species: Homo sapiens [TaxId:9606]
    Gene: HSBMHC
    Database cross-references and differences (RAF-indexed):
    • Uniprot P12883 (3-End)
      • cloning artifact (2)
      • engineered (89)
    Domains in SCOPe 2.08: d2fxob2, d2fxob3
  • Chain 'C':
    Compound: Myosin heavy chain, cardiac muscle beta isoform
    Species: Homo sapiens [TaxId:9606]
    Gene: HSBMHC
    Database cross-references and differences (RAF-indexed):
    • Uniprot P12883 (3-End)
      • cloning artifact (1-2)
      • engineered (89)
    Domains in SCOPe 2.08: d2fxoc2, d2fxoc3
  • Chain 'D':
    Compound: Myosin heavy chain, cardiac muscle beta isoform
    Species: Homo sapiens [TaxId:9606]
    Gene: HSBMHC
    Database cross-references and differences (RAF-indexed):
    • Uniprot P12883 (3-128)
      • cloning artifact (2)
      • engineered (89)
    Domains in SCOPe 2.08: d2fxod2, d2fxod3

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2fxoA (A:)
gsspllksaerekemasmkeeftrlkealeksearrkeleekmvsllqekndlqlqvqae
qdnladaeercdqliknkiqleakvkemnkrledeeemnaeltakkrkledecselkrdi
ddleltlak

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2fxoB (B:)
gsspllksaerekemasmkeeftrlkealeksearrkeleekmvsllqekndlqlqvqae
qdnladaeercdqliknkiqleakvkemnkrledeeemnaeltakkrkledecselkrdi
ddleltlak

    Sequence, based on observed residues (ATOM records): (download) 
    >2fxoB (B:)
spllksaerekemasmkeeftrlkealeksearrkeleekmvsllqekndlqlqvqaeqd
nladaeercdqliknkiqleakvkemnkrledeeemnaeltakkrkledecselkrdidd
leltl

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2fxoC (C:)
gsspllksaerekemasmkeeftrlkealeksearrkeleekmvsllqekndlqlqvqae
qdnladaeercdqliknkiqleakvkemnkrledeeemnaeltakkrkledecselkrdi
ddleltlak

    Sequence, based on observed residues (ATOM records): (download) 
    >2fxoC (C:)
sspllksaerekemasmkeeftrlkealeksearrkeleekmvsllqekndlqlqvqaeq
dnladaeercdqliknkiqleakvkemnkrledeeemnaeltakkrkledecselkrdid
dleltla

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2fxoD (D:)
gsspllksaerekemasmkeeftrlkealeksearrkeleekmvsllqekndlqlqvqae
qdnladaeercdqliknkiqleakvkemnkrledeeemnaeltakkrkledecselkrdi
ddleltlak

    Sequence, based on observed residues (ATOM records): (download) 
    >2fxoD (D:)
spllksaerekemasmkeeftrlkealeksearrkeleekmvsllqekndlqlqvqaeqd
nladaeercdqliknkiqleakvkemnkrledeeemnaeltakkrkledecselkrdidd
leltlak