PDB entry 2fwn

View 2fwn on RCSB PDB site
Description: Phosphorylation of an active site serine in a ThDP-dependent enzyme by phosphonate inactivation
Class: lyase
Keywords: lyase, carbon-carbon, decarboxylase, phophonated, mandelate catabolism, thiamine diphosphate, high resolution
Deposited on 2006-02-02, released 2006-12-19
The last revision prior to the SCOPe 2.05 freeze date was dated 2008-05-20, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.4 Å
R-factor: 0.108
AEROSPACI score: 0.76 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Benzoylformate decarboxylase
    Species: Pseudomonas putida [TaxId:303]
    Gene: MDLC
    Database cross-references and differences (RAF-indexed):
    • Uniprot P20906
      • modified residue (25)
    Domains in SCOPe 2.05: d2fwna1, d2fwna2, d2fwna3
  • Heterogens: MG, CA, TDP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2fwnA (A:)
masvhgttyellrrqgidtvfgnpgsnelpflkdfpedfryilalqeacvvgiadgyaqa
srkpafinlhsaagtgnamgalsnawnshsplivtagqqtramigvealltnvdaanlpr
plvkwsyepasaaevphamsraihmasmapqgpvylsvpyddwdkdadpqshhlfdrhvs
ssvrlndqdldilvkalnsasnpaivlgpdvdaananadcvmlaerlkapvwvapsaprc
pfptrhpcfrglmpagiaaisqlleghdvvlvigapvfryhqydpgqylkpgtrlisvtc
dpleaarapmgdaivadigamasalanlveessrqlptaapepakvdqdagrlhpetvfd
tlndmapenaiylneststtaqmwqrlnmrnpgsyyfcaagglgfalpaaigvqlaeper
qviavigdgsanysisalwtaaqyniptifvimnngtygalrwfagvleaenvpgldvpg
idfralakgygvqalkadnleqlkgslqealsakgpvlievstvspvk

    Sequence, based on observed residues (ATOM records): (download) 
    >2fwnA (A:)
asvhgttyellrrqgidtvfgnpgsnelpflkdfpedfryilalqeacvvgiadgyaqas
rkpafinlhsaagtgnamgalsnawnshsplivtagqqtramigvealltnvdaanlprp
lvkwsyepasaaevphamsraihmasmapqgpvylsvpyddwdkdadpqshhlfdrhvss
svrlndqdldilvkalnsasnpaivlgpdvdaananadcvmlaerlkapvwvapsaprcp
fptrhpcfrglmpagiaaisqlleghdvvlvigapvfryhqydpgqylkpgtrlisvtcd
pleaarapmgdaivadigamasalanlveessrqlptaapepakvdqdagrlhpetvfdt
lndmapenaiylneststtaqmwqrlnmrnpgsyyfcaagglgfalpaaigvqlaeperq
viavigdgsanysisalwtaaqyniptifvimnngtygalrwfagvleaenvpgldvpgi
dfralakgygvqalkadnleqlkgslqealsakgpvlievstvs