PDB entry 2fw6

View 2fw6 on RCSB PDB site
Description: Structure of PurE (N5-carboxyaminoimidazole ribonucleotide mutase) mutant H59N from the acidophilic bacterium Acetobacter aceti, at pH 5.4
Class: Lyase
Keywords: acidophile, PurE, purine biosynthesis, Lyase
Deposited on 2006-02-01, released 2006-06-13
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 1.85 Å
R-factor: 0.172
AEROSPACI score: 0.52 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: N5-carboxyaminoimidazole ribonucleotide mutase
    Species: Acetobacter aceti [TaxId:435]
    Gene: purE
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q2QJL3
      • engineered (59)
    Domains in SCOPe 2.08: d2fw6a_
  • Chain 'B':
    Compound: N5-carboxyaminoimidazole ribonucleotide mutase
    Species: Acetobacter aceti [TaxId:435]
    Gene: purE
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q2QJL3
      • engineered (59)
    Domains in SCOPe 2.08: d2fw6b_
  • Heterogens: CIT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2fw6A (A:)
mmsetaplpsassaledkaasapvvgiimgsqsdwetmrhadallteleiphetlivsan
rtpdrladyartaaerglnviiagaggaahlpgmcaawtrlpvlgvpvesralkgmdsll
sivqmpggvpvgtlaigasgaknaallaasilalynpalaarletwralqtasvpnspit
edk

    Sequence, based on observed residues (ATOM records): (download) 
    >2fw6A (A:)
sapvvgiimgsqsdwetmrhadallteleiphetlivsanrtpdrladyartaaerglnv
iiagaggaahlpgmcaawtrlpvlgvpvesralkgmdsllsivqmpggvpvgtlaigasg
aknaallaasilalynpalaarletwralqtasvpnspi

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2fw6B (B:)
mmsetaplpsassaledkaasapvvgiimgsqsdwetmrhadallteleiphetlivsan
rtpdrladyartaaerglnviiagaggaahlpgmcaawtrlpvlgvpvesralkgmdsll
sivqmpggvpvgtlaigasgaknaallaasilalynpalaarletwralqtasvpnspit
edk

    Sequence, based on observed residues (ATOM records): (download) 
    >2fw6B (B:)
sapvvgiimgsqsdwetmrhadallteleiphetlivsanrtpdrladyartaaerglnv
iiagaggaahlpgmcaawtrlpvlgvpvesralkgmdsllsivqmpggvpvgtlaigasg
aknaallaasilalynpalaarletwralqtasvpnspit