PDB entry 2fun

View 2fun on RCSB PDB site
Description: alternative p35-caspase-8 complex
Class: apoptosis/hydrolase
Keywords: apoptosis/hydrolase
Deposited on 2006-01-27, released 2006-06-27
The last revision prior to the SCOP 1.73 freeze date was dated 2006-06-27, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 3 Å
R-factor: 0.229
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Early 35 kDa protein
    Species: Autographa californica nuclear polyhedrosis virus
    Gene: P35
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d2funa1
  • Chain 'B':
    Compound: caspase-8
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d2funb1
  • Chain 'C':
    Compound: Early 35 kDa protein
    Species: Autographa californica nuclear polyhedrosis virus
    Gene: P35
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d2func1
  • Chain 'D':
    Compound: caspase-8
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d2fund1
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2funA (A:)
cvifpveidvsqtiirdcqvdkqtrelvyinkimntqltkpvlmmfnisgpirsvtrknn
nlrdrikskvdeqfdqlerdysdqmdgfhdsikyfkdehysvscqngsvlkskfakilks
hdytdkksieayekyclpklvderndyyvavcvlkpgfengsnqvlsfeynpignkvivp
faheindtglyeydvvayvdsvqfdgeqfeefvqslilpssfknsekvlyyneasknksm
iykalefttesswgksekynwkifcngfiydkkskvlyvklhnvtsalnknvilntik

    Sequence, based on observed residues (ATOM records): (download) 
    >2funA (A:)
cvifpveidvsqtiirdcqvdkqtrelvyinkimntqltkpvlmmfnisgpirsvtrknn
nlrdrikskvdeqfdqlerdysdqmdikyfkdehysvscqngsvlkskfakilkshdytd
kksieayekyclpklvderndyyvavcvlkpgfengsnqvlsfeynpignkvivpfahei
ndtglyeydvvayvdsvqfdgeqfeefvqslilpssfknsekvlyyneasknksmiykal
efttesswgksekynwkifcngfiydkkskvlyvklhnvtsalnknvilntik

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2funB (B:)
ldkvyqmkskprgycliinnhnfakarekvpklhsirdrngthldagaltttfeelhfei
kphhdctveqiyeilkiyqlmdhsnmdcficcilshgdkgiiygtdgqeapiyeltsqft
glkcpslagkpkvffiqacqgdnyqkgipvetdseeqpylemdlsspqtryipdeadfll
gmatvnncvsyrnpaegtwyiqslcqslrercprgddiltiltevnyevsnkddkknmgk
qmpqptftlrkklvfpsd

    Sequence, based on observed residues (ATOM records): (download) 
    >2funB (B:)
ldkvyqmkskprgycliinnhnfakarekvpklhsirdrngthldagaltttfeelhfei
kphhdctveqiyeilkiyqlmdhsnmdcficcilshgdkgiiygtdgqeapiyeltsqft
glkcpslagkpkvffiqacqgdnyqkgipvetdtryipdeadfllgmatvnncvsyrnpa
egtwyiqslcqslrercprgddiltiltevnyevsnkddkknmgkqmpqptftlrkklvf
psd

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2funC (C:)
cvifpveidvsqtiirdcqvdkqtrelvyinkimntqltkpvlmmfnisgpirsvtrknn
nlrdrikskvdeqfdqlerdysdqmdgfhdsikyfkdehysvscqngsvlkskfakilks
hdytdkksieayekyclpklvderndyyvavcvlkpgfengsnqvlsfeynpignkvivp
faheindtglyeydvvayvdsvqfdgeqfeefvqslilpssfknsekvlyyneasknksm
iykalefttesswgksekynwkifcngfiydkkskvlyvklhnvtsalnknvilntik

    Sequence, based on observed residues (ATOM records): (download) 
    >2funC (C:)
cvifpveidvsqtiirdcqvdkqtrelvyinkimntqltkpvlmmfnisgpirsvtrknn
nlrdrikskvdeqfdqlerdysdqmdikyfkdehysvscqngsvlkskfakilkshdytd
kksieayekyclpklvderndyyvavcvlkpgfengsnqvlsfeynpignkvivpfahei
ndtglyeydvvayvdsvqfdgeqfeefvqslilpssfknsekvlyyneasknksmiykal
efttesswgksekynwkifcngfiydkkskvlyvklhnvtsalnknvilntik

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2funD (D:)
ldkvyqmkskprgycliinnhnfakarekvpklhsirdrngthldagaltttfeelhfei
kphhdctveqiyeilkiyqlmdhsnmdcficcilshgdkgiiygtdgqeapiyeltsqft
glkcpslagkpkvffiqacqgdnyqkgipvetdseeqpylemdlsspqtryipdeadfll
gmatvnncvsyrnpaegtwyiqslcqslrercprgddiltiltevnyevsnkddkknmgk
qmpqptftlrkklvfpsd

    Sequence, based on observed residues (ATOM records): (download) 
    >2funD (D:)
ldkvyqmkskprgycliinnhnfakarekvpklhsirdrngthldagaltttfeelhfei
kphhdctveqiyeilkiyqlmdhsnmdcficcilshgdkgiiygtdgqeapiyeltsqft
glkcpslagkpkvffiqacqgdnyqkgipvetdtryipdeadfllgmatvnncvsyrnpa
egtwyiqslcqslrercprgddiltiltevnyevsnkddkknmgkqmpqptftlrkklvf
p