PDB entry 2fto
View 2fto on RCSB PDB site
Description: Y94F mutant of thymidylate synthase bound to thymidine-5'-phosphate and 10-propargyl-5,8-dideazafolid acid
Class: transferase
Keywords: methyltransferase, TRANSFERASE
Deposited on
2006-01-24, released
2006-05-02
The last revision prior to the SCOPe 2.06 freeze date was dated
2011-07-13, with a file datestamp of
2011-05-08.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.159
AEROSPACI score: 0.46
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'X':
Compound: Thymidylate synthase
Species: Escherichia coli [TaxId:562]
Gene: thyA
Database cross-references and differences (RAF-indexed):
- Uniprot P0A884 (0-263)
- modified residue (0)
- engineered (93)
Domains in SCOPe 2.06: d2ftox_ - Heterogens: PO4, TMP, CB3, HOH