PDB entry 2fsl

View 2fsl on RCSB PDB site
Description: mitogen activated protein kinase p38alpha (D176A+F327S) activating mutant form-A
Class: transferase
Keywords: mitogen activated protein kinase, p38, active mutants, lipids, MAP kinase insertion, autophosphorylation, TRANSFERASE
Deposited on 2006-01-23, released 2006-12-05
The last revision prior to the SCOPe 2.02 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: 0.22
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'X':
    Compound: Mitogen-activated protein kinase 14
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q16539
      • engineered (333)
    Domains in SCOPe 2.02: d2fslx_
  • Heterogens: BOG, HOH

PDB Chain Sequences:

  • Chain 'X':
    Sequence, based on SEQRES records: (download) 
    >2fslX (X:)
mahhhhhhsqerptfyrqelnktiwevperyqnlspvgsgaygsvcaafdtktglrvavk
klsrpfqsiihakrtyrelrllkhmkhenviglldvftparsleefndvylvthlmgadl
nnivkcqkltddhvqfliyqilrglkyihsadiihrdlkpsnlavnedcelkildfglar
htademtgyvatrwyrapeimlnwmhynqtvdiwsvgcimaelltgrtlfpgtdhidqlk
lilrlvgtpgaellkkissesarnyiqsltqmpkmnfanvfiganplavdllekmlvlds
dkritaaqalahayfaqyhdpddepvadpydqssesrdllidewksltydevisfvpppl
dqeemes

    Sequence, based on observed residues (ATOM records): (download) 
    >2fslX (X:)
erptfyrqelnktiwevperyqnlspvgsgagsvcaafdtktglrvavkklsrpfqsiih
akrtyrelrllkhmkhenviglldvftparsleefndvylvthlmgadlnnqkltddhvq
fliyqilrglkyihsadiihrdlkpsnlavnedcelkildvatrwyrapeimlnwmhynq
tvdiwsvgcimaelltgrtlfpgtdhidqlklilrlvgtpgaellkkissesarnyiqsl
tqmpkmnfanvfiganplavdllekmlvldsdkritaaqalahayfaqyhdpddepvadp
ydqssesrdllidewksltydevisfvpppld