PDB entry 2frv

View 2frv on RCSB PDB site
Description: crystal structure of the oxidized form of ni-fe hydrogenase
Class: oxidoreductase
Keywords: oxidoreductase, ni-fe hydrogenase
Deposited on 1997-06-10, released 1998-06-17
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-03-24, with a file datestamp of 2009-03-20.
Experiment type: XRAY
Resolution: 2.54 Å
R-factor: 0.202
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: periplasmic hydrogenase
    Species: Desulfovibrio gigas [TaxId:879]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P12943 (Start-263)
      • conflict (23)
      • conflict (88)
    Domains in SCOPe 2.07: d2frva_
  • Chain 'B':
    Compound: periplasmic hydrogenase
    Species: Desulfovibrio gigas [TaxId:879]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P12944 (Start-535)
      • conflict (143)
      • conflict (331)
      • conflict (481)
      • conflict (496)
    Domains in SCOPe 2.07: d2frvb_
  • Chain 'C':
    Compound: periplasmic hydrogenase
    Species: Desulfovibrio gigas [TaxId:879]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P12943 (Start-263)
      • conflict (23)
      • conflict (88)
    Domains in SCOPe 2.07: d2frvc_
  • Chain 'D':
    Compound: periplasmic hydrogenase
    Species: Desulfovibrio gigas [TaxId:879]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P12944 (Start-535)
      • conflict (143)
      • conflict (331)
      • conflict (481)
      • conflict (496)
    Domains in SCOPe 2.07: d2frvd_
  • Chain 'E':
    Compound: periplasmic hydrogenase
    Species: Desulfovibrio gigas [TaxId:879]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P12943 (Start-263)
      • conflict (23)
      • conflict (88)
    Domains in SCOPe 2.07: d2frve_
  • Chain 'F':
    Compound: periplasmic hydrogenase
    Species: Desulfovibrio gigas [TaxId:879]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P12944 (Start-535)
      • conflict (143)
      • conflict (331)
      • conflict (481)
      • conflict (496)
    Domains in SCOPe 2.07: d2frvf_
  • Chain 'G':
    Compound: periplasmic hydrogenase
    Species: Desulfovibrio gigas [TaxId:879]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P12943 (Start-263)
      • conflict (23)
      • conflict (88)
    Domains in SCOPe 2.07: d2frvg_
  • Chain 'H':
    Compound: periplasmic hydrogenase
    Species: Desulfovibrio gigas [TaxId:879]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P12944 (Start-535)
      • conflict (143)
      • conflict (331)
      • conflict (481)
      • conflict (496)
    Domains in SCOPe 2.07: d2frvh_
  • Chain 'I':
    Compound: periplasmic hydrogenase
    Species: Desulfovibrio gigas [TaxId:879]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P12943 (Start-263)
      • conflict (23)
      • conflict (88)
    Domains in SCOPe 2.07: d2frvi_
  • Chain 'J':
    Compound: periplasmic hydrogenase
    Species: Desulfovibrio gigas [TaxId:879]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P12944 (Start-535)
      • conflict (143)
      • conflict (331)
      • conflict (481)
      • conflict (496)
    Domains in SCOPe 2.07: d2frvj_
  • Chain 'L':
    Compound: periplasmic hydrogenase
    Species: Desulfovibrio gigas [TaxId:879]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P12944 (Start-535)
      • conflict (143)
      • conflict (331)
      • conflict (481)
      • conflict (496)
    Domains in SCOPe 2.07: d2frvl_
  • Chain 'S':
    Compound: periplasmic hydrogenase
    Species: Desulfovibrio gigas [TaxId:879]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P12943 (Start-263)
      • conflict (23)
      • conflict (88)
    Domains in SCOPe 2.07: d2frvs_
  • Heterogens: NI, MG, SF4, F3S, FCO, O, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2frvA (A:)
    ltakkrpsvvylhnaectgcsesvlrtvdpyvdelildvismdyhetlmagaghaveeal
    heaikgdfvcvieggipmgdggywgkvggrnmydicaevapkakaviaigtcatyggvqa
    akpnptgtvgvnealgklgvkainiagcppnpmnfvgtvvhlltkgmpeldkqgrpvmff
    getvhdncprlkhfeagefatsfgspeakkgyclyelgckgpdtynncpkqlfnqvnwpv
    qaghpciacsepnfwdlyspfysa
    

    Sequence, based on observed residues (ATOM records): (download)
    >2frvA (A:)
    kkrpsvvylhnaectgcsesvlrtvdpyvdelildvismdyhetlmagaghaveealhea
    ikgdfvcvieggipmgdggywgkvggrnmydicaevapkakaviaigtcatyggvqaakp
    nptgtvgvnealgklgvkainiagcppnpmnfvgtvvhlltkgmpeldkqgrpvmffget
    vhdncprlkhfeagefatsfgspeakkgyclyelgckgpdtynncpkqlfnqvnwpvqag
    hpciacsepnfwdlyspfysa
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >2frvB (B:)
    msemqgnkivvdpitrieghlrieveveggkiknawsmstlfrglemilkgrdprdaqhf
    tqracgvctyvhalasvravdncvgvkipenatlmrnltmgaqymhdhlvhfyhlhaldw
    vnvanalnadpakaarlandlspkkttteslkavqakvkalvesgqlgiftnayflgghp
    ayvlpaevdliatahylealrvqvkaaramaifgaknphtqftvvggctnydslrperia
    efrklykevrefieqvyitdllavagfyknwagigktsnfltcgefptdeydlnsrytpq
    gviwgndlskvddfnpdlieehvkyswyegagahhpykgvtkpkwtefhgedryswmkap
    rykgeafevgplasvlvayakkheptvkavdlvlktlgvgpealfstlgrtaargiqclt
    aaqevevwldkleanvkagkddlytdwqyptesqgvgfvnaprgmlshwivqrggkienf
    qlvvpstwnlgprcaegklsaveqaligtpiadpkrpveilrtvhsydpciacgvh
    

    Sequence, based on observed residues (ATOM records): (download)
    >2frvB (B:)
    nkivvdpitrieghlrieveveggkiknawsmstlfrglemilkgrdprdaqhftqracg
    vctyvhalasvravdncvgvkipenatlmrnltmgaqymhdhlvhfyhlhaldwvnvana
    lnadpakaarlandlspkkttteslkavqakvkalvesgqlgiftnayflgghpayvlpa
    evdliatahylealrvqvkaaramaifgaknphtqftvvggctnydslrperiaefrkly
    kevrefieqvyitdllavagfyknwagigktsnfltcgefptdeydlnsrytpqgviwgn
    dlskvddfnpdlieehvkyswyegagahhpykgvtkpkwtefhgedryswmkaprykgea
    fevgplasvlvayakkheptvkavdlvlktlgvgpealfstlgrtaargiqcltaaqeve
    vwldkleanvkagkddlytdwqyptesqgvgfvnaprgmlshwivqrggkienfqlvvps
    twnlgprcaegklsaveqaligtpiadpkrpveilrtvhsydpciacgvh
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >2frvC (C:)
    ltakkrpsvvylhnaectgcsesvlrtvdpyvdelildvismdyhetlmagaghaveeal
    heaikgdfvcvieggipmgdggywgkvggrnmydicaevapkakaviaigtcatyggvqa
    akpnptgtvgvnealgklgvkainiagcppnpmnfvgtvvhlltkgmpeldkqgrpvmff
    getvhdncprlkhfeagefatsfgspeakkgyclyelgckgpdtynncpkqlfnqvnwpv
    qaghpciacsepnfwdlyspfysa
    

    Sequence, based on observed residues (ATOM records): (download)
    >2frvC (C:)
    kkrpsvvylhnaectgcsesvlrtvdpyvdelildvismdyhetlmagaghaveealhea
    ikgdfvcvieggipmgdggywgkvggrnmydicaevapkakaviaigtcatyggvqaakp
    nptgtvgvnealgklgvkainiagcppnpmnfvgtvvhlltkgmpeldkqgrpvmffget
    vhdncprlkhfeagefatsfgspeakkgyclyelgckgpdtynncpkqlfnqvnwpvqag
    hpciacsepnfwdlyspfysa
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >2frvD (D:)
    msemqgnkivvdpitrieghlrieveveggkiknawsmstlfrglemilkgrdprdaqhf
    tqracgvctyvhalasvravdncvgvkipenatlmrnltmgaqymhdhlvhfyhlhaldw
    vnvanalnadpakaarlandlspkkttteslkavqakvkalvesgqlgiftnayflgghp
    ayvlpaevdliatahylealrvqvkaaramaifgaknphtqftvvggctnydslrperia
    efrklykevrefieqvyitdllavagfyknwagigktsnfltcgefptdeydlnsrytpq
    gviwgndlskvddfnpdlieehvkyswyegagahhpykgvtkpkwtefhgedryswmkap
    rykgeafevgplasvlvayakkheptvkavdlvlktlgvgpealfstlgrtaargiqclt
    aaqevevwldkleanvkagkddlytdwqyptesqgvgfvnaprgmlshwivqrggkienf
    qlvvpstwnlgprcaegklsaveqaligtpiadpkrpveilrtvhsydpciacgvh
    

    Sequence, based on observed residues (ATOM records): (download)
    >2frvD (D:)
    nkivvdpitrieghlrieveveggkiknawsmstlfrglemilkgrdprdaqhftqracg
    vctyvhalasvravdncvgvkipenatlmrnltmgaqymhdhlvhfyhlhaldwvnvana
    lnadpakaarlandlspkkttteslkavqakvkalvesgqlgiftnayflgghpayvlpa
    evdliatahylealrvqvkaaramaifgaknphtqftvvggctnydslrperiaefrkly
    kevrefieqvyitdllavagfyknwagigktsnfltcgefptdeydlnsrytpqgviwgn
    dlskvddfnpdlieehvkyswyegagahhpykgvtkpkwtefhgedryswmkaprykgea
    fevgplasvlvayakkheptvkavdlvlktlgvgpealfstlgrtaargiqcltaaqeve
    vwldkleanvkagkddlytdwqyptesqgvgfvnaprgmlshwivqrggkienfqlvvps
    twnlgprcaegklsaveqaligtpiadpkrpveilrtvhsydpciacgvh
    

  • Chain 'E':
    Sequence, based on SEQRES records: (download)
    >2frvE (E:)
    ltakkrpsvvylhnaectgcsesvlrtvdpyvdelildvismdyhetlmagaghaveeal
    heaikgdfvcvieggipmgdggywgkvggrnmydicaevapkakaviaigtcatyggvqa
    akpnptgtvgvnealgklgvkainiagcppnpmnfvgtvvhlltkgmpeldkqgrpvmff
    getvhdncprlkhfeagefatsfgspeakkgyclyelgckgpdtynncpkqlfnqvnwpv
    qaghpciacsepnfwdlyspfysa
    

    Sequence, based on observed residues (ATOM records): (download)
    >2frvE (E:)
    kkrpsvvylhnaectgcsesvlrtvdpyvdelildvismdyhetlmagaghaveealhea
    ikgdfvcvieggipmgdggywgkvggrnmydicaevapkakaviaigtcatyggvqaakp
    nptgtvgvnealgklgvkainiagcppnpmnfvgtvvhlltkgmpeldkqgrpvmffget
    vhdncprlkhfeagefatsfgspeakkgyclyelgckgpdtynncpkqlfnqvnwpvqag
    hpciacsepnfwdlyspfysa
    

  • Chain 'F':
    Sequence, based on SEQRES records: (download)
    >2frvF (F:)
    msemqgnkivvdpitrieghlrieveveggkiknawsmstlfrglemilkgrdprdaqhf
    tqracgvctyvhalasvravdncvgvkipenatlmrnltmgaqymhdhlvhfyhlhaldw
    vnvanalnadpakaarlandlspkkttteslkavqakvkalvesgqlgiftnayflgghp
    ayvlpaevdliatahylealrvqvkaaramaifgaknphtqftvvggctnydslrperia
    efrklykevrefieqvyitdllavagfyknwagigktsnfltcgefptdeydlnsrytpq
    gviwgndlskvddfnpdlieehvkyswyegagahhpykgvtkpkwtefhgedryswmkap
    rykgeafevgplasvlvayakkheptvkavdlvlktlgvgpealfstlgrtaargiqclt
    aaqevevwldkleanvkagkddlytdwqyptesqgvgfvnaprgmlshwivqrggkienf
    qlvvpstwnlgprcaegklsaveqaligtpiadpkrpveilrtvhsydpciacgvh
    

    Sequence, based on observed residues (ATOM records): (download)
    >2frvF (F:)
    nkivvdpitrieghlrieveveggkiknawsmstlfrglemilkgrdprdaqhftqracg
    vctyvhalasvravdncvgvkipenatlmrnltmgaqymhdhlvhfyhlhaldwvnvana
    lnadpakaarlandlspkkttteslkavqakvkalvesgqlgiftnayflgghpayvlpa
    evdliatahylealrvqvkaaramaifgaknphtqftvvggctnydslrperiaefrkly
    kevrefieqvyitdllavagfyknwagigktsnfltcgefptdeydlnsrytpqgviwgn
    dlskvddfnpdlieehvkyswyegagahhpykgvtkpkwtefhgedryswmkaprykgea
    fevgplasvlvayakkheptvkavdlvlktlgvgpealfstlgrtaargiqcltaaqeve
    vwldkleanvkagkddlytdwqyptesqgvgfvnaprgmlshwivqrggkienfqlvvps
    twnlgprcaegklsaveqaligtpiadpkrpveilrtvhsydpciacgvh
    

  • Chain 'G':
    Sequence, based on SEQRES records: (download)
    >2frvG (G:)
    ltakkrpsvvylhnaectgcsesvlrtvdpyvdelildvismdyhetlmagaghaveeal
    heaikgdfvcvieggipmgdggywgkvggrnmydicaevapkakaviaigtcatyggvqa
    akpnptgtvgvnealgklgvkainiagcppnpmnfvgtvvhlltkgmpeldkqgrpvmff
    getvhdncprlkhfeagefatsfgspeakkgyclyelgckgpdtynncpkqlfnqvnwpv
    qaghpciacsepnfwdlyspfysa
    

    Sequence, based on observed residues (ATOM records): (download)
    >2frvG (G:)
    kkrpsvvylhnaectgcsesvlrtvdpyvdelildvismdyhetlmagaghaveealhea
    ikgdfvcvieggipmgdggywgkvggrnmydicaevapkakaviaigtcatyggvqaakp
    nptgtvgvnealgklgvkainiagcppnpmnfvgtvvhlltkgmpeldkqgrpvmffget
    vhdncprlkhfeagefatsfgspeakkgyclyelgckgpdtynncpkqlfnqvnwpvqag
    hpciacsepnfwdlyspfysa
    

  • Chain 'H':
    Sequence, based on SEQRES records: (download)
    >2frvH (H:)
    msemqgnkivvdpitrieghlrieveveggkiknawsmstlfrglemilkgrdprdaqhf
    tqracgvctyvhalasvravdncvgvkipenatlmrnltmgaqymhdhlvhfyhlhaldw
    vnvanalnadpakaarlandlspkkttteslkavqakvkalvesgqlgiftnayflgghp
    ayvlpaevdliatahylealrvqvkaaramaifgaknphtqftvvggctnydslrperia
    efrklykevrefieqvyitdllavagfyknwagigktsnfltcgefptdeydlnsrytpq
    gviwgndlskvddfnpdlieehvkyswyegagahhpykgvtkpkwtefhgedryswmkap
    rykgeafevgplasvlvayakkheptvkavdlvlktlgvgpealfstlgrtaargiqclt
    aaqevevwldkleanvkagkddlytdwqyptesqgvgfvnaprgmlshwivqrggkienf
    qlvvpstwnlgprcaegklsaveqaligtpiadpkrpveilrtvhsydpciacgvh
    

    Sequence, based on observed residues (ATOM records): (download)
    >2frvH (H:)
    nkivvdpitrieghlrieveveggkiknawsmstlfrglemilkgrdprdaqhftqracg
    vctyvhalasvravdncvgvkipenatlmrnltmgaqymhdhlvhfyhlhaldwvnvana
    lnadpakaarlandlspkkttteslkavqakvkalvesgqlgiftnayflgghpayvlpa
    evdliatahylealrvqvkaaramaifgaknphtqftvvggctnydslrperiaefrkly
    kevrefieqvyitdllavagfyknwagigktsnfltcgefptdeydlnsrytpqgviwgn
    dlskvddfnpdlieehvkyswyegagahhpykgvtkpkwtefhgedryswmkaprykgea
    fevgplasvlvayakkheptvkavdlvlktlgvgpealfstlgrtaargiqcltaaqeve
    vwldkleanvkagkddlytdwqyptesqgvgfvnaprgmlshwivqrggkienfqlvvps
    twnlgprcaegklsaveqaligtpiadpkrpveilrtvhsydpciacgvh
    

  • Chain 'I':
    Sequence, based on SEQRES records: (download)
    >2frvI (I:)
    ltakkrpsvvylhnaectgcsesvlrtvdpyvdelildvismdyhetlmagaghaveeal
    heaikgdfvcvieggipmgdggywgkvggrnmydicaevapkakaviaigtcatyggvqa
    akpnptgtvgvnealgklgvkainiagcppnpmnfvgtvvhlltkgmpeldkqgrpvmff
    getvhdncprlkhfeagefatsfgspeakkgyclyelgckgpdtynncpkqlfnqvnwpv
    qaghpciacsepnfwdlyspfysa
    

    Sequence, based on observed residues (ATOM records): (download)
    >2frvI (I:)
    kkrpsvvylhnaectgcsesvlrtvdpyvdelildvismdyhetlmagaghaveealhea
    ikgdfvcvieggipmgdggywgkvggrnmydicaevapkakaviaigtcatyggvqaakp
    nptgtvgvnealgklgvkainiagcppnpmnfvgtvvhlltkgmpeldkqgrpvmffget
    vhdncprlkhfeagefatsfgspeakkgyclyelgckgpdtynncpkqlfnqvnwpvqag
    hpciacsepnfwdlyspfysa
    

  • Chain 'J':
    Sequence, based on SEQRES records: (download)
    >2frvJ (J:)
    msemqgnkivvdpitrieghlrieveveggkiknawsmstlfrglemilkgrdprdaqhf
    tqracgvctyvhalasvravdncvgvkipenatlmrnltmgaqymhdhlvhfyhlhaldw
    vnvanalnadpakaarlandlspkkttteslkavqakvkalvesgqlgiftnayflgghp
    ayvlpaevdliatahylealrvqvkaaramaifgaknphtqftvvggctnydslrperia
    efrklykevrefieqvyitdllavagfyknwagigktsnfltcgefptdeydlnsrytpq
    gviwgndlskvddfnpdlieehvkyswyegagahhpykgvtkpkwtefhgedryswmkap
    rykgeafevgplasvlvayakkheptvkavdlvlktlgvgpealfstlgrtaargiqclt
    aaqevevwldkleanvkagkddlytdwqyptesqgvgfvnaprgmlshwivqrggkienf
    qlvvpstwnlgprcaegklsaveqaligtpiadpkrpveilrtvhsydpciacgvh
    

    Sequence, based on observed residues (ATOM records): (download)
    >2frvJ (J:)
    nkivvdpitrieghlrieveveggkiknawsmstlfrglemilkgrdprdaqhftqracg
    vctyvhalasvravdncvgvkipenatlmrnltmgaqymhdhlvhfyhlhaldwvnvana
    lnadpakaarlandlspkkttteslkavqakvkalvesgqlgiftnayflgghpayvlpa
    evdliatahylealrvqvkaaramaifgaknphtqftvvggctnydslrperiaefrkly
    kevrefieqvyitdllavagfyknwagigktsnfltcgefptdeydlnsrytpqgviwgn
    dlskvddfnpdlieehvkyswyegagahhpykgvtkpkwtefhgedryswmkaprykgea
    fevgplasvlvayakkheptvkavdlvlktlgvgpealfstlgrtaargiqcltaaqeve
    vwldkleanvkagkddlytdwqyptesqgvgfvnaprgmlshwivqrggkienfqlvvps
    twnlgprcaegklsaveqaligtpiadpkrpveilrtvhsydpciacgvh
    

  • Chain 'L':
    Sequence, based on SEQRES records: (download)
    >2frvL (L:)
    msemqgnkivvdpitrieghlrieveveggkiknawsmstlfrglemilkgrdprdaqhf
    tqracgvctyvhalasvravdncvgvkipenatlmrnltmgaqymhdhlvhfyhlhaldw
    vnvanalnadpakaarlandlspkkttteslkavqakvkalvesgqlgiftnayflgghp
    ayvlpaevdliatahylealrvqvkaaramaifgaknphtqftvvggctnydslrperia
    efrklykevrefieqvyitdllavagfyknwagigktsnfltcgefptdeydlnsrytpq
    gviwgndlskvddfnpdlieehvkyswyegagahhpykgvtkpkwtefhgedryswmkap
    rykgeafevgplasvlvayakkheptvkavdlvlktlgvgpealfstlgrtaargiqclt
    aaqevevwldkleanvkagkddlytdwqyptesqgvgfvnaprgmlshwivqrggkienf
    qlvvpstwnlgprcaegklsaveqaligtpiadpkrpveilrtvhsydpciacgvh
    

    Sequence, based on observed residues (ATOM records): (download)
    >2frvL (L:)
    nkivvdpitrieghlrieveveggkiknawsmstlfrglemilkgrdprdaqhftqracg
    vctyvhalasvravdncvgvkipenatlmrnltmgaqymhdhlvhfyhlhaldwvnvana
    lnadpakaarlandlspkkttteslkavqakvkalvesgqlgiftnayflgghpayvlpa
    evdliatahylealrvqvkaaramaifgaknphtqftvvggctnydslrperiaefrkly
    kevrefieqvyitdllavagfyknwagigktsnfltcgefptdeydlnsrytpqgviwgn
    dlskvddfnpdlieehvkyswyegagahhpykgvtkpkwtefhgedryswmkaprykgea
    fevgplasvlvayakkheptvkavdlvlktlgvgpealfstlgrtaargiqcltaaqeve
    vwldkleanvkagkddlytdwqyptesqgvgfvnaprgmlshwivqrggkienfqlvvps
    twnlgprcaegklsaveqaligtpiadpkrpveilrtvhsydpciacgvh
    

  • Chain 'S':
    Sequence, based on SEQRES records: (download)
    >2frvS (S:)
    ltakkrpsvvylhnaectgcsesvlrtvdpyvdelildvismdyhetlmagaghaveeal
    heaikgdfvcvieggipmgdggywgkvggrnmydicaevapkakaviaigtcatyggvqa
    akpnptgtvgvnealgklgvkainiagcppnpmnfvgtvvhlltkgmpeldkqgrpvmff
    getvhdncprlkhfeagefatsfgspeakkgyclyelgckgpdtynncpkqlfnqvnwpv
    qaghpciacsepnfwdlyspfysa
    

    Sequence, based on observed residues (ATOM records): (download)
    >2frvS (S:)
    kkrpsvvylhnaectgcsesvlrtvdpyvdelildvismdyhetlmagaghaveealhea
    ikgdfvcvieggipmgdggywgkvggrnmydicaevapkakaviaigtcatyggvqaakp
    nptgtvgvnealgklgvkainiagcppnpmnfvgtvvhlltkgmpeldkqgrpvmffget
    vhdncprlkhfeagefatsfgspeakkgyclyelgckgpdtynncpkqlfnqvnwpvqag
    hpciacsepnfwdlyspfysa