PDB entry 2fll

View 2fll on RCSB PDB site
Description: Ternary complex of human DNA polymerase iota with DNA and dTTP
Class: replication/DNA
Keywords: DNA polymerase, lesion bypass, Y-family, ternary complex, p6522, REPLICATION-DNA COMPLEX
Deposited on 2006-01-06, released 2006-12-12
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.228
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA polymerase iota
    Species: Homo sapiens [TaxId:9606]
    Gene: POLI, RAD30B
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2flla1, d2flla2
  • Chain 'P':
    Compound: DNA primer strand
  • Chain 'T':
    Compound: DNA template strand
  • Heterogens: MG, TTP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2fllA (A:)
meladvgaaassqgvhdqvlptpnassrvivhvdldcfyaqvemisnpelkdkplgvqqk
ylvvtcnyearklgvkklmnvrdakekcpqlvlvngedltryremsykvtelleefspvv
erlgfdenfvdltemvekrlqqlqsdelsavtvsghvynnqsinlldvlhirllvgsqia
aemreamynqlgltgcagvasnkllaklvsgvfkpnqqtvllpescqhlihslnhikeip
gigyktakclealginsvrdlqtfspkilekelgisvaqriqklsfgednspvilsgppq
sfseedsfkkcsseveaknkieellasllnrvcqdgrkphtvrliirryssekhygresr
qcpipshviqklgtgnydvmtpmvdilmklfrnmvnvkmpfhltllsvcfcnlkalntak

    Sequence, based on observed residues (ATOM records): (download) 
    >2fllA (A:)
assrvivhvdldcfyaqvemisnpelkdkplgvqqkylvvtcnyearklgvkklmnvrda
kekcpqlvlvngedltryremsykvtelleefspvverlgfdenfvdltemvekrlqqlq
sdelsavtvsghvynnqsinlldvlhirllvgsqiaaemreamynqlgltgcagvasnkl
laklvsgvfkpnqqtvllpescqhlihslnhikeipgigyktakclealginsvrdlqtf
spkilekelgisvaqriqklsfgednspvilsgppqsfseedsfkkcsseveaknkieel
lasllnrvcqdgrkphtvrliirryssekhygresrqcpipshviqvmtpmvdilmklfr
nmtllsvcfcnlk

  • Chain 'P':
    No sequence available.

  • Chain 'T':
    No sequence available.