PDB entry 2fkl

View 2fkl on RCSB PDB site
Description: Structure of the Alzheimer's Amyloid Precursor Protein (APP) Copper Binding Domain (Residues 126- 189 of APP)
Class: metal binding protein
Keywords: Alpha-Beta Two-layered Sandwich, METAL BINDING PROTEIN
Deposited on 2006-01-04, released 2007-01-16
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.222
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Amyloid beta A4 protein precursor
    Species: Homo sapiens [TaxId:9606]
    Gene: APP
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2fkla_
  • Chain 'B':
    Compound: Amyloid beta A4 protein precursor
    Species: Homo sapiens [TaxId:9606]
    Gene: APP
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2fklb_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2fklA (A:)
sdallvpdkckflhqermdvcethlhwhtvaketcsekstnlhdygmllpcgidkfrgve
fvccpl

    Sequence, based on observed residues (ATOM records): (download) 
    >2fklA (A:)
allvpdkckflhqermdvcethlhwhtvaketcsekstnlhdygmllpcgidkfrgvefv
ccpl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2fklB (B:)
sdallvpdkckflhqermdvcethlhwhtvaketcsekstnlhdygmllpcgidkfrgve
fvccpl

    Sequence, based on observed residues (ATOM records): (download) 
    >2fklB (B:)
allvpdkckflhqermdvcethlhwhtvaketcsekstnlhdygmllpcgidkfrgvefv
ccpl