PDB entry 2fju

View 2fju on RCSB PDB site
Description: Activated Rac1 bound to its effector phospholipase C beta 2
Class: signaling protein,apoptosis/hydrolase
Keywords: Protein-protein complex, SIGNALING PROTEIN,APOPTOSIS/HYDROLASE COMPLEX
Deposited on 2006-01-03, released 2006-11-21
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.208
AEROSPACI score: 0.39 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ras-related c3 botulinum toxin substrate 1
    Species: Homo sapiens [TaxId:9606]
    Gene: RAC1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2fjua_
  • Chain 'B':
    Compound: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 2
    Species: Homo sapiens [TaxId:9606]
    Gene: PLCB2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2fjub1, d2fjub2, d2fjub3, d2fjub4
  • Heterogens: MG, CA, GSP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2fjuA (A:)
    mqaikcvvvgdgavgktcllisyttnafpgeyiptvfdnysanvmvdgkpvnlglwdtag
    qedydrlrplsypqtdvflicfslvspasfenvrakwypevrhhcpntpiilvgtkldlr
    ddkdtieklkekkltpitypqglamakeigavkylecsaltqrglktvfdeairavls
    

    Sequence, based on observed residues (ATOM records): (download)
    >2fjuA (A:)
    mqaikcvvvgdgavgktcllisyttnafpgeyiptvfdnysanvmvdgkpvnlglwdtag
    qedydrlrplsypqtdvflicfslvspasfenvrakwypevrhhcpntpiilvgtkldlr
    ddkdtieklkekkltpitypqglamakeigavkylecsaltqrglktvfdeairavl
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >2fjuB (B:)
    msllnpvllppkvkaylsqgerfikwddettvaspvilrvdpkgyylywtyqskemefld
    itsirdtrfgkfakmpksqklrdvfnmdfpdnsfllktltvvsgpdmvdltfhnfvsyke
    nvgkawaedvlalvkhpltanasrstfldkilvklkmqlnsegkipvknffqmfpadrkr
    veaalsachlpkgkndainpedfpepvyksflmslcprpeideiftsyhakakpymtkeh
    ltkfinqkqrdsrlnsllfpparpdqvqglidkyepsginaqrgqlspegmvwflcgpen
    svlaqdklllhhdmtqplnhyfinsshntyltagqfsglssaemyrqvllsgcrcveldc
    wkgkppdeepiithgftmttdiffkeaieaiaesafktspypiilsfenhvdsprqqakm
    aeycrtifgdmllteplekfplkpgvplpspedlrgkiliknkknqfsgptssskdtgge
    aegssppsapavwageegteleeeeveeeeeeesgnldeeeikkmqsdegtaglevtaye
    emsslvnyiqptkfvsfefsaqknrsyvissftelkaydllskasvqfvdynkrqmsriy
    pkgtrmdssnympqmfwnagcqmvalnfqtmdlpmqqnmavfefngqsgyllkhefmrrp
    dkqfnpfsvdridvvvattlsitvisgqflsersvrtyvevelfglpgdpkrryrtklsp
    stnsinpvwkeepfvfekilmpelaslrvavmeegnkflghriipinalnsgyhhlclhs
    esnmpltmpalfiflemkd
    

    Sequence, based on observed residues (ATOM records): (download)
    >2fjuB (B:)
    pkvkaylsqgerfikwddettvaspvilrvdpkgyylywtyqskemeflditsirdtrfg
    kfakmpksqklrdvfnmdfpdnsfllktltvvsgpdmvdltfhnfvsykenvgkawaedv
    lalvkhpltanasrstfldkilvklkmqlnsegkipvknffqmfpadrkrveaalsachl
    pkgkndainpedfpepvyksflmslcprpeideiftsymtkehltkfinqkqrdqglidk
    yepsgqlspegmvwflcgpensvlaqdklllhhdmtqplnhyfinsshntyltagqfsgl
    ssaemyrqvllsgcrcveldcwkgkppdeepiithgftmttdiffkeaieaiaesafkts
    pypiilsfenhvdsprqqakmaeycrtifgdmllteplekfplkpgvplpspedlrgkil
    iknkkeesgnldeeeikkmqsdegtaglevtayeemsslvnyiqptkfvsfefsaqknrs
    yvissftelkaydllskasvqfvdynkrqmsriypkgtrmdssnympqmfwnagcqmval
    nfqtmdlpmqqnmavfefngqsgyllkhefmrrpttlsitvisgqflsersvrtyvevel
    fglpgdpkrryrtklspstnsinpvwkeepfvfekilmpelaslrvavmeegnkflghri
    ipinalnsgyhhlclhsesnmpltmpalfiflemkd