SCOPe 2.07: Structural Classification of Proteins

PDB entry 2fjf

View 2fjf on RCSB PDB site
Description: Structure of the G6 Fab, a phage derived VEGF binding Fab
Class: immune system
Keywords: Antibody, Fab, Dodecamer, IMMUNE SYSTEM
Deposited on 2006-01-02, released 2006-02-07
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.65 Å
R-factor: 0.2
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

Chain 'A':
Compound: Light Chain of a VEGF binding Antibody
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Uniprot Q6GMX8 (0-End)
Domains in SCOPe 2.07: d2fjfa1, d2fjfa2
Chain 'B':
Compound: Heavy Chain of a VEGF binding Antibody
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Uniprot Q569F4 (0-End)
Domains in SCOPe 2.07: d2fjfb1, d2fjfb2
Chain 'C':
Compound: Light Chain of a VEGF binding Antibody
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Uniprot Q6GMX8 (0-End)
Domains in SCOPe 2.07: d2fjfc1, d2fjfc2
Chain 'D':
Compound: Heavy Chain of a VEGF binding Antibody
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Uniprot Q569F4 (0-End)
Domains in SCOPe 2.07: d2fjfd1, d2fjfd2
Chain 'E':
Compound: Light Chain of a VEGF binding Antibody
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Uniprot Q6GMX8 (0-End)
Domains in SCOPe 2.07: d2fjfe1, d2fjfe2
Chain 'F':
Compound: Heavy Chain of a VEGF binding Antibody
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Uniprot Q569F4 (0-End)
Domains in SCOPe 2.07: d2fjff1, d2fjff2
Chain 'G':
Compound: Light Chain of a VEGF binding Antibody
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Uniprot Q6GMX8 (0-End)
Domains in SCOPe 2.07: d2fjfg1, d2fjfg2
Chain 'H':
Compound: Heavy Chain of a VEGF binding Antibody
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Uniprot Q569F4 (0-End)
Domains in SCOPe 2.07: d2fjfh1, d2fjfh2
Chain 'I':
Compound: Heavy Chain of a VEGF binding Antibody
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Uniprot Q569F4 (0-End)
Domains in SCOPe 2.07: d2fjfi1, d2fjfi2
Chain 'J':
Compound: Light Chain of a VEGF binding Antibody
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Uniprot Q6GMX8 (0-End)
Domains in SCOPe 2.07: d2fjfj1, d2fjfj2
Chain 'K':
Compound: Heavy Chain of a VEGF binding Antibody
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Uniprot Q569F4 (0-End)
Domains in SCOPe 2.07: d2fjfk1, d2fjfk2
Chain 'L':
Compound: Light Chain of a VEGF binding Antibody
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Uniprot Q6GMX8 (0-End)
Domains in SCOPe 2.07: d2fjfl1, d2fjfl2
Chain 'M':
Compound: Light Chain of a VEGF binding Antibody
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Uniprot Q6GMX8 (0-End)
Domains in SCOPe 2.07: d2fjfm1, d2fjfm2
Chain 'N':
Compound: Heavy Chain of a VEGF binding Antibody
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Uniprot Q569F4 (0-End)
Domains in SCOPe 2.07: d2fjfn1, d2fjfn2
Chain 'O':
Compound: Light Chain of a VEGF binding Antibody
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Uniprot Q6GMX8 (0-End)
Domains in SCOPe 2.07: d2fjfo1, d2fjfo2
Chain 'P':
Compound: Heavy Chain of a VEGF binding Antibody
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Uniprot Q569F4 (0-End)
Domains in SCOPe 2.07: d2fjfp1, d2fjfp2
Chain 'Q':
Compound: Light Chain of a VEGF binding Antibody
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Uniprot Q6GMX8 (0-End)
Domains in SCOPe 2.07: d2fjfq1, d2fjfq2
Chain 'R':
Compound: Heavy Chain of a VEGF binding Antibody
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Uniprot Q569F4 (0-End)
Domains in SCOPe 2.07: d2fjfr1, d2fjfr2
Chain 'S':
Compound: Light Chain of a VEGF binding Antibody
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Uniprot Q6GMX8 (0-End)
Domains in SCOPe 2.07: d2fjfs1, d2fjfs2
Chain 'T':
Compound: Heavy Chain of a VEGF binding Antibody
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Uniprot Q569F4 (0-End)
Domains in SCOPe 2.07: d2fjft1, d2fjft2
Chain 'U':
Compound: Light Chain of a VEGF binding Antibody
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Uniprot Q6GMX8 (0-End)
Domains in SCOPe 2.07: d2fjfu1, d2fjfu2
Chain 'V':
Compound: Heavy Chain of a VEGF binding Antibody
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Uniprot Q569F4 (0-End)
Domains in SCOPe 2.07: d2fjfv1, d2fjfv2
Chain 'W':
Compound: Light Chain of a VEGF binding Antibody
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Uniprot Q6GMX8 (0-End)
Domains in SCOPe 2.07: d2fjfw1, d2fjfw2
Chain 'X':
Compound: Heavy Chain of a VEGF binding Antibody
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Uniprot Q569F4 (0-End)
Domains in SCOPe 2.07: d2fjfx1, d2fjfx2
Heterogens: HOH

PDB Chain Sequences:

Chain 'A':
Sequence, based on SEQRES records: (download)

>2fjfA (A:)
diqmtqspsslsasvgdrvtitcrasqdvstavawyqqkpgkapklliysasflysgvps
rfsgsgsgtdftltisslqpedfatyycqqsyttpptfgqgtkveikrtvaapsvfifpp
sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
lskadyekhkvyacevthqglsspvtksfnrgec