PDB entry 2fit

View 2fit on RCSB PDB site
Description: fhit (fragile histidine triad protein)
Class: chromosomal translocation
Keywords: fhit, fragile histidine triad protein, putative human tumor suppressor, advanced photon source, aps, hit protein family, pkci, chromosomal translocation
Deposited on 1997-05-17, released 1997-11-19
The last revision prior to the SCOPe 2.05 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.222
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: fragile histidine protein
    Species: Homo sapiens [TaxId:9606]
    Gene: FHIT
    Database cross-references and differences (RAF-indexed):
    • Uniprot P49789 (Start-146)
      • modified residue (81)
      • conflict (134)
    Domains in SCOPe 2.05: d2fita_
  • Heterogens: FRU, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2fitA (A:)
msfrfgqhlikpsvvflktelsfalvnrkpvvpghvlvcplrpverfhdlrpdevadlfq
ttqrvgtvvekhfhgtsltfsmqdgpeagqtvkhvhvhvlprkagdfhrndsiyeelqkh
dkedfpaswrseeemaaeaaalrvyfq

    Sequence, based on observed residues (ATOM records): (download) 
    >2fitA (A:)
sfrfgqhlikpsvvflktelsfalvnrkpvvpghvlvcplrpverfhdlrpdevadlfqt
tqrvgtvvekhfhgtsltfsmqdgpeagqtvkhvhvhvlprkagdfhfpaswrseeemaa
eaaalrvyfq