PDB entry 2fhr

View 2fhr on RCSB PDB site
Description: Trypanosoma Rangeli Sialidase In Complex With 2,3- Difluorosialic Acid (Covalent Intermediate)
Class: hydrolase
Keywords: beta-propeller, covalent enzyme-intermediate complex, beta-sandwich, hydrolase
Deposited on 2005-12-26, released 2006-01-17
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: N/A
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: sialidase
    Species: Trypanosoma rangeli [TaxId:5698]
    Database cross-references and differences (RAF-indexed):
    • GB AAC95493 (14-End)
      • cloning artifact (13)
      • see remark 999 (63)
      • see remark 999 (199)
      • see remark 999 (385)
      • see remark 999 (619)
    Domains in SCOPe 2.08: d2fhra1, d2fhra2, d2fhra3
  • Heterogens: SO4, FSI, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2fhrA (A:)
mggshhhhhhgmaslapgssrvelfkrknstvpfeesngtirervvhsfriptivnvdgv
mvaiadaryetsfdnsfietavkysvddgatwntqiaiknsrassvsrvmdatvivkgnk
lyilvgsfnktrnswtqhrdgsdwepllvvgevtksaangkttatiswgkpvslkplfpa
efdgiltkefiggvgaaivasngnlvypvqiadmggrvftkimyseddgntwkfaegrsk
fgcsepavlewegkliinnrvdgnrrlvyessdmgktwvealgtlshvwtnsptsnqqdc
qssfvavtiegkrvmlfthplnlkgrwmrdrlhlwmtdnqrifdvgqisigdensgyssv
lykddklyslheintndvyslvfvrligelqlmksvvrtwkeednhlasictpvvpatpp
skggcgaavptaglvgflshsangsvwedvyrcvdanvanaervpnglkfngvgggavwp
varqgqtrryqfanyrftlvatvtidelpkgtspllgaglegpgdakllglsydknrqwr
plygaapasptgswelhkkyhvvltmadrqgsvyvdgqplagsgntvvrgatlpdishfy
iggprskgaptdsrvtvtnvvlynrrlnsseirtlflsqdmigtdggagtaa

    Sequence, based on observed residues (ATOM records): (download) 
    >2fhrA (A:)
slapgssrvelfkrknstvpfeesngtirervvhsfriptivnvdgvmvaiadaryetsf
dnsfietavkysvddgatwntqiaiknsrassvsrvmdatvivkgnklyilvgsfnktrn
swtqhrdgsdwepllvvgevtksaangkttatiswgkpvslkplfpaefdgiltkefigg
vgaaivasngnlvypvqiadmggrvftkimyseddgntwkfaegrskfgcsepavleweg
kliinnrvdgnrrlvyessdmgktwvealgtlshvwtnsptsnqqdcqssfvavtiegkr
vmlfthplnlkgrwmrdrlhlwmtdnqrifdvgqisigdensgyssvlykddklyslhei
ntndvyslvfvrligelqlmksvvrtwkeednhlasictpvkggcgaavptaglvgflsh
sangsvwedvyrcvdanvanaervpnglkfngvgggavwpvarqgqtrryqfanyrftlv
atvtidelpkgtspllgaglegpgdakllglsydknrqwrplygaapasptgswelhkky
hvvltmadrqgsvyvdgqplagsgntvvrgatlpdishfyiggprskgaptdsrvtvtnv
vlynrrlnsseirtlflsqdmigtd