PDB entry 2ff2

View 2ff2 on RCSB PDB site
Description: Crystal structure of Trypanosoma vivax nucleoside hydrolase co-crystallized with ImmucillinH
Class: Hydrolase
Keywords: Rossmann fold, loop ordering, aromatic stacking, Hydrolase
Deposited on 2005-12-18, released 2006-05-23
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.167
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: IAG-nucleoside hydrolase
    Species: Trypanosoma vivax [TaxId:5699]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9GPQ4 (Start-338)
      • see remark 999 (312)
    Domains in SCOPe 2.07: d2ff2a_
  • Chain 'B':
    Compound: IAG-nucleoside hydrolase
    Species: Trypanosoma vivax [TaxId:5699]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9GPQ4 (12-338)
      • expression tag (12)
      • see remark 999 (312)
      • expression tag (12)
    Domains in SCOPe 2.07: d2ff2b2, d2ff2b3
  • Heterogens: CA, NI, IMH, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2ff2A (A:)
mrgsphhhhhhgsaknvvldhdgnlddfvamvllasntekvrligalctdadcfvengfn
vtgkimclmhnnmnlplfpigksaatavnpfpkewrclaknmddmpilnipenvelwdki
kaenekyegqqlladlvmnseekvticvtgplsnvawcidkygekftskveecvimggav
dvrgnvflpstdgtaewniywdpasaktvfgcpglrrimfsldstntvpvrspyvqrfge
qtnfllsilvgtmwamcthcellrdgdgyyawdaltaayvvdqkvanvdpvpidvvvdkq
pnegatvrtdaenypltfvarnpeaeffldmllrsarac

    Sequence, based on observed residues (ATOM records): (download) 
    >2ff2A (A:)
aknvvldhdgnlddfvamvllasntekvrligalctdadcfvengfnvtgkimclmhnnm
nlplfpigksaatavnpfpkewrclaknmddmpilnipenvelwdkikaenekyegqqll
adlvmnseekvticvtgplsnvawcidkygekftskveecvimggavdvrgnvflpstdg
taewniywdpasaktvfgcpglrrimfsldstntvpvrspyvqrfgeqtnfllsilvgtm
wamcthcellrdgdgyyawdaltaayvvdqkvanvdpvpidvvvdkqpnegatvrtdaen
ypltfvarnpeaeffldmllrsarac

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2ff2B (B:)
mrgsphhhhhhgsaknvvldhdgnlddfvamvllasntekvrligalctdadcfvengfn
vtgkimclmhnnmnlplfpigksaatavnpfpkewrclaknmddmpilnipenvelwdki
kaenekyegqqlladlvmnseekvticvtgplsnvawcidkygekftskveecvimggav
dvrgnvflpstdgtaewniywdpasaktvfgcpglrrimfsldstntvpvrspyvqrfge
qtnfllsilvgtmwamcthcellrdgdgyyawdaltaayvvdqkvanvdpvpidvvvdkq
pnegatvrtdaenypltfvarnpeaeffldmllrsarac

    Sequence, based on observed residues (ATOM records): (download) 
    >2ff2B (B:)
saknvvldhdgnlddfvamvllasntekvrligalctdadcfvengfnvtgkimclmhnn
mnlplfpigksaatavnpfpkewrclaknmddmpilnipenvelwdkikaenekyegqql
ladlvmnseekvticvtgplsnvawcidkygekftskveecvimggavdvrgnvflpstd
gtaewniywdpasaktvfgcpglrrimfsldstntvpvrspyvqrfgeqtnfllsilvgt
mwamcthcellrdgdgyyawdaltaayvvdqkvanvdpvpidvvvdkqpnegatvrtdae
nypltfvarnpeaeffldmllrsarac