PDB entry 2ff1

View 2ff1 on RCSB PDB site
Description: Crystal structure of Trypanosoma vivax nucleoside hydrolase soaked with ImmucillinH
Class: Hydrolase
Keywords: Rossmann fold, disordered loops, aromatic stacking, Hydrolase
Deposited on 2005-12-18, released 2006-05-23
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.07 Å
R-factor: 0.178
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: IAG-nucleoside hydrolase
    Species: Trypanosoma vivax [TaxId:5699]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9GPQ4 (12-338)
      • expression tag (12)
      • see remark 999 (225)
    Domains in SCOPe 2.07: d2ff1a2, d2ff1a3
  • Chain 'B':
    Compound: IAG-nucleoside hydrolase
    Species: Trypanosoma vivax [TaxId:5699]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9GPQ4 (12-338)
      • expression tag (12)
      • see remark 999 (225)
    Domains in SCOPe 2.07: d2ff1b2, d2ff1b3
  • Heterogens: CA, IMH, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2ff1A (A:)
mrgsphhhhhhgsaknvvldhdgnlddfvamvllasntekvrligalctdadcfvengfn
vtgkimclmhnnmnlplfpigksaatavnpfpkewrclaknmddmpilnipenvelwdki
kaenekyegqqlladlvmnseekvticvtgplsnvawcidkygekftskveecvimggav
dvrgnvflpstdgtaewniywdpasaktvfgcpglrrimfsldstntvpvrspyvqrfge
qtnfllsilvgtmwamcthcellrdgdgyyawdaltaayvvdqkvanvdpvpidvvvdkq
pnegatvrtdaenypltfvarnpeaeffldmllrsarac

    Sequence, based on observed residues (ATOM records): (download) 
    >2ff1A (A:)
saknvvldhdgnlddfvamvllasntekvrligalctdadcfvengfnvtgkimclmhnn
mnlplfpigksaatavnpfpkewrclaknmddmpilnipenvelwdkikaenekyegqql
ladlvmnseekvticvtgplsnvawcidkygekftskveecvimggavdvrgnvflpstd
gtaewniywdpasaktvfgcpglrrimfsldstntvpvrspyvqrfgeqtnfllsilvgt
mwamyawdaltaayvvdqkvanvdpvpidvvvdkqpnegatvrtdaenypltfvarnpea
effldmllrsarac

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2ff1B (B:)
mrgsphhhhhhgsaknvvldhdgnlddfvamvllasntekvrligalctdadcfvengfn
vtgkimclmhnnmnlplfpigksaatavnpfpkewrclaknmddmpilnipenvelwdki
kaenekyegqqlladlvmnseekvticvtgplsnvawcidkygekftskveecvimggav
dvrgnvflpstdgtaewniywdpasaktvfgcpglrrimfsldstntvpvrspyvqrfge
qtnfllsilvgtmwamcthcellrdgdgyyawdaltaayvvdqkvanvdpvpidvvvdkq
pnegatvrtdaenypltfvarnpeaeffldmllrsarac

    Sequence, based on observed residues (ATOM records): (download) 
    >2ff1B (B:)
saknvvldhdgnlddfvamvllasntekvrligalctdadcfvengfnvtgkimclmhnn
mnlplfpigksaatavnpfpkewrclaknmddmpilnipenvelwdkikaenekyegqql
ladlvmnseekvticvtgplsnvawcidkygekftskveecvimggavdvrgnvflpstd
gtaewniywdpasaktvfgcpglrrimfsldstntvpvrspyvqrfgeqtnfllsilvgt
mwamgyyawdaltaayvvdqkvanvdpvpidvvvdkqpnegatvrtdaenypltfvarnp
eaeffldmllrsarac