PDB entry 2fdz
View 2fdz on RCSB PDB site
Description: Crystal structure of a potent small molecule inhibitor bound to cathepsin K
Class: Hydrolase
Keywords: osteoporosis, structure-guided drug design, proteae
Deposited on
2005-12-14, released
2006-11-28
The last revision prior to the SCOPe 2.08 freeze date was dated
2007-04-24, with a file datestamp of
2007-06-01.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.171
AEROSPACI score: 0.46
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: cathepsin k
Species: HOMO SAPIENS
Gene: CTSK, CTSO, CTSO2
Database cross-references and differences (RAF-indexed):
- Uniprot P43235 (0-214)
- conflict (4)
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Domains in SCOPe 2.08: d2fdza_