PDB entry 2f6m

View 2f6m on RCSB PDB site
Description: Structure of a Vps23-C:Vps28-N subcomplex
Class: transport protein
Keywords: endosomes, trafficking complex, Vps23, Vps28, Vacuole Protein Sorting, ESCRT protein complexes, Endosomal Sorting Complex Required for Transport, ESCRT-I, Ubiquitin, TSG101
Deposited on 2005-11-29, released 2006-04-18
The last revision prior to the SCOP 1.73 freeze date was dated 2006-04-18, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.242
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: suppressor protein stp22 of temperature-sensitive alpha-factor receptor and arginine permease
    Species: Saccharomyces cerevisiae
    Gene: STP22, VPS23
    Database cross-references and differences (RAF-indexed):
    • Uniprot P25604 (1-64)
      • cloning artifact (0)
      • engineered (23)
    Domains in SCOP 1.73: d2f6ma1
  • Chain 'B':
    Compound: vacuolar protein sorting-associated protein vps28
    Species: Saccharomyces cerevisiae
    Gene: VPS28, VPT28
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q02767 (3-108)
      • cloning artifact (2)
      • engineered (91)
    Domains in SCOP 1.73: d2f6mb1
  • Chain 'C':
    Compound: suppressor protein stp22 of temperature-sensitive alpha-factor receptor and arginine permease
    Species: Saccharomyces cerevisiae
    Gene: STP22, VPS23
    Database cross-references and differences (RAF-indexed):
    • Uniprot P25604 (1-End)
      • cloning artifact (0)
      • engineered (23)
    Domains in SCOP 1.73: d2f6mc1
  • Chain 'D':
    Compound: vacuolar protein sorting-associated protein vps28
    Species: Saccharomyces cerevisiae
    Gene: VPS28, VPT28
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q02767
      • engineered (91)
    Domains in SCOP 1.73: d2f6md1
  • Heterogens: MG, DDQ, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2f6mA (A:)
mtdglnqlynlvaqdyaltdtiealsrmlhrgtipldtfvkqgrelarqqflvrwhiqri
tspls

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2f6mB (B:)
gamdisqlfhdevplfdnsitskdkevietlseiysivitldhvekaylkdsiddtqytn
tvdkllkqfkvylnsqnkeeinkhfqsieafadtynitasnaitrlerg

    Sequence, based on observed residues (ATOM records): (download) 
    >2f6mB (B:)
mdisqlfhdevplfdnsitskdkevietlseiysivitldhvekaylkdsiddtqytntv
dkllkqfkvylnsqnkeeinkhfqsieafadtynitasnaitrlerg

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2f6mC (C:)
mtdglnqlynlvaqdyaltdtiealsrmlhrgtipldtfvkqgrelarqqflvrwhiqri
tspls

    Sequence, based on observed residues (ATOM records): (download) 
    >2f6mC (C:)
mtdglnqlynlvaqdyaltdtiealsrmlhrgtipldtfvkqgrelarqqflvrwhiqri
tsp

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2f6mD (D:)
gamdisqlfhdevplfdnsitskdkevietlseiysivitldhvekaylkdsiddtqytn
tvdkllkqfkvylnsqnkeeinkhfqsieafadtynitasnaitrlerg

    Sequence, based on observed residues (ATOM records): (download) 
    >2f6mD (D:)
qlfhdevplfdnsitskdkevietlseiysivitldhvekaylkdsiddtqytntvdkll
kqfkvylnsqnkeeinkhfqsieafadtynitasnaitrler