PDB entry 2f6f
View 2f6f on RCSB PDB site
Description: The structure of the S295F mutant of human PTP1B
Class: hydrolase
Keywords: Phosphatase, ligand binding, mutations, HYDROLASE
Deposited on
2005-11-29, released
2005-12-06
The last revision prior to the SCOPe 2.08 freeze date was dated
2009-02-24, with a file datestamp of
2009-03-01.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.186
AEROSPACI score: 0.46
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Tyrosine-protein phosphatase, non-receptor type 1
Species: Homo sapiens [TaxId:9606]
Gene: PTPN1, PTP1B
Database cross-references and differences (RAF-indexed):
- Uniprot P18031 (4-301)
- cloning artifact (0-3)
- engineered (298)
Domains in SCOPe 2.08: d2f6fa1, d2f6fa2 - Heterogens: CL, MG, HOH