PDB entry 2f5a

View 2f5a on RCSB PDB site
Description: crystal structure of fab' from the hiv-1 neutralizing antibody 2f5
Class: immunoglobulin
Keywords: fab, hiv-1 neutralization, gp41, immunoglobulin
Deposited on 1999-04-08, released 2003-07-15
The last revision prior to the SCOPe 2.05 freeze date was dated 2009-12-29, with a file datestamp of 2009-12-24.
Experiment type: XRAY
Resolution: 2.05 Å
R-factor: 0.235
AEROSPACI score: 0.39 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'H':
    Compound: protein (antibody 2f5 (heavy chain))
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2F5A (0-231)
    Domains in SCOPe 2.05: d2f5ah1, d2f5ah2
  • Chain 'L':
    Compound: protein (antibody 2f5 (light chain))
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2F5A (0-212)
    Domains in SCOPe 2.05: d2f5al1, d2f5al2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'H':
    Sequence, based on SEQRES records: (download)
    >2f5aH (H:)
    ritlkesgpplvkptqtltltcsfsgfslsdfgvgvgwirqppgkalewlaiiysdddkr
    yspslntrltitkdtsknqvvlvmtrvspvdtatyfcahrrgpttlaaaaaaagpvnamd
    vwgqgitvtisststkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgalts
    gvhtfpavlqssglyslssvvtvpssslgtqtytcnvnhkpsntkvdkrvep
    

    Sequence, based on observed residues (ATOM records): (download)
    >2f5aH (H:)
    ritlkesgpplvkptqtltltcsfsgfslsdfgvgvgwirqppgkalewlaiiysdddkr
    yspslntrltitkdtsknqvvlvmtrvspvdtatyfcahrrgpttlaaaaaaagpvnamd
    vwgqgitvtisststkgpsvfplapssggtaalgclvkdyfpepvtvswnsgaltsgvht
    fpavlqssglyslssvvtvpssslgtqtytcnvnhkpsntkvdkrvep
    

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records: (download)
    >2f5aL (L:)
    alqltqspsslsasvgdrititcrasqgvtsalawyrqkpgsppqlliydasslesgvps
    rfsgsgsgteftltistlrpedfatyycqqlhfyphtfgggtrvdvrrtvaapsvfifpp
    sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
    lskadyekhkvyecevthqglsspvtksfnrge