PDB entry 2f57

View 2f57 on RCSB PDB site
Description: Crystal Structure Of The Human P21-Activated Kinase 5
Class: transferase
Keywords: Pak5, Kinase domains, GroupII PAKs, Structural Genomics, Structural Genomics Consortium, SGC, TRANSFERASE
Deposited on 2005-11-25, released 2005-12-13
The last revision prior to the SCOPe 2.06 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.155
AEROSPACI score: 0.55 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Serine/threonine-protein kinase PAK 7
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9P286 (22-End)
      • cloning artifact (15-21)
      • modified residue (199)
    Domains in SCOPe 2.06: d2f57a1, d2f57a2
  • Chain 'B':
    Compound: Serine/threonine-protein kinase PAK 7
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9P286 (22-End)
      • cloning artifact (16-21)
      • modified residue (199)
    Domains in SCOPe 2.06: d2f57b1, d2f57b2
  • Heterogens: TRS, 23D, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2f57A (A:)
mgsshhhhhhssgrenlyfqsmsrvsheqfraalqlvvspgdpreylanfikigegstgi
vciatekhtgkqvavkkmdlrkqqrrellfnevvimrdyhhdnvvdmyssylvgdelwvv
mefleggaltdivthtrmneeqiatvclsvlralsylhnqgvihrdiksdsilltsdgri
klsdfgfcaqvskevpkrkslvgtpywmapevisrlpygtevdiwslgimviemidgepp
yfnepplqamrrirdslpprvkdlhkvssvlrgfldlmlvrepsqrataqellghpflkl
agppscivplmrqyrhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2f57A (A:)
nlyfqsmsrvsheqfraalqlvvspgdpreylanfikigegstgivciatekhtgkqvav
kkmdlrkqqrrellfnevvimrdyhhdnvvdmyssylvgdelwvvmefleggaltdivth
trmneeqiatvclsvlralsylhnqgvihrdiksdsilltsdgriklsdfgfcaqvskev
pkrkslvgtpywmapevisrlpygtevdiwslgimviemidgeppyfnepplqamrrird
slpprvkdlhkvssvlrgfldlmlvrepsqrataqellghpflklagppscivplmrq

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2f57B (B:)
mgsshhhhhhssgrenlyfqsmsrvsheqfraalqlvvspgdpreylanfikigegstgi
vciatekhtgkqvavkkmdlrkqqrrellfnevvimrdyhhdnvvdmyssylvgdelwvv
mefleggaltdivthtrmneeqiatvclsvlralsylhnqgvihrdiksdsilltsdgri
klsdfgfcaqvskevpkrkslvgtpywmapevisrlpygtevdiwslgimviemidgepp
yfnepplqamrrirdslpprvkdlhkvssvlrgfldlmlvrepsqrataqellghpflkl
agppscivplmrqyrhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2f57B (B:)
lyfqsmsrvsheqfraalqlvvspgdpreylanfikigegstgivciatekhtgkqvavk
kmdlrkqqrrellfnevvimrdyhhdnvvdmyssylvgdelwvvmefleggaltdivtht
rmneeqiatvclsvlralsylhnqgvihrdiksdsilltsdgriklsdfgfcaqvskevp
krkslvgtpywmapevisrlpygtevdiwslgimviemidgeppyfnepplqamrrirds
lpprvkdlhkvssvlrgfldlmlvrepsqrataqellghpflklagppscivplmrqyrh