PDB entry 2f4j
View 2f4j on RCSB PDB site
Description: Structure of the Kinase Domain of an Imatinib-Resistant Abl Mutant in Complex with the Aurora Kinase Inhibitor VX-680
Class: transferase
Keywords: kinase, kinase inhibitor, abl, TRANSFERASE
Deposited on
2005-11-23, released
2006-01-24
The last revision prior to the SCOPe 2.08 freeze date was dated
2017-10-18, with a file datestamp of
2017-10-13.
Experiment type: XRAY
Resolution: 1.91 Å
R-factor: N/A
AEROSPACI score: 0.34
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Proto-oncogene tyrosine-protein kinase ABL1
Species: Homo sapiens [TaxId:9606]
Gene: ABL1, ABL, JTK7
Database cross-references and differences (RAF-indexed):
- GB NP_005148 (0-286)
- engineered (169)
- cloning artifact (1)
Domains in SCOPe 2.08: d2f4ja_ - Heterogens: VX6, HOH