PDB entry 2f3c

View 2f3c on RCSB PDB site
Description: Crystal structure of infestin 1, a Kazal-type serineprotease inhibitor, in complex with trypsin
Class: hydrolase/hydrolase inhibitor
Keywords: serine protease - inhibitor complex, Kazal-type domain, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
Deposited on 2005-11-20, released 2006-12-05
The last revision prior to the SCOPe 2.02 freeze date was dated 2012-06-20, with a file datestamp of 2012-06-15.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.17
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'E':
    Compound: cationic trypsin
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d2f3ce_
  • Chain 'I':
    Compound: thrombin inhibitor infestin
    Species: Triatoma infestans [TaxId:30076]
    Database cross-references and differences (RAF-indexed):
    • GB AAK57342
    Domains in SCOPe 2.02: d2f3ci1
  • Heterogens: SO4, CA, HOH

PDB Chain Sequences:

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >2f3cE (E:)
ivggytcgantvpyqvslnsgyhfcggslinsqwvvsaahcyksgiqvrlgedninvveg
neqfisasksivhpsynsntlnndimliklksaaslnsrvasislptscasagtqclisg
wgntkssgtsypdvlkclkapilsdsscksaypgqitsnmfcagyleggkdscqgdsggp
vvcsgklqgivswgsgcaqknkpgvytkvcnyvswikqtiasn

    Sequence, based on observed residues (ATOM records): (download) 
    >2f3cE (E:)
ivggytcgantvpyqvslnsgyhfcggslinsqwvvsaahcyksgiqvrlgedninvveg
neqfisasksivhpsynsntlnndimliklksaaslnvasislptscasagtqclisgwg
ntkssgtsypdvlkclkapilsdsscksaypgqitsnmfcagyleggkdscqgdsggpvv
csgklqgivswgsgcaqknkpgvytkvcnyvswikqtiasn

  • Chain 'I':
    Sequence, based on SEQRES records: (download) 
    >2f3cI (I:)
leendcacprvlhrvcgsdgntysnpctldcakhegkpdlvqvhegpcdpndhdf

    Sequence, based on observed residues (ATOM records): (download) 
    >2f3cI (I:)
dcacprvlhrvcgsdgntysnpctldcakhegkpdlvqvhegpcdp