PDB entry 2f3b

View 2f3b on RCSB PDB site
Description: Mechanism of displacement of a catalytically essential loop from the active site of fructose-1,6-bisphosphatase
Class: hydrolase
Keywords: allostery, allosteric regulation, loop diengagement, enzyme catalysis, FBPase, fructose-1,6-bisphosphatase, HYDROLASE
Deposited on 2005-11-20, released 2006-04-25
The last revision prior to the SCOPe 2.07 freeze date was dated 2014-02-05, with a file datestamp of 2014-01-31.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.222
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Fructose-1,6-bisphosphatase 1
    Species: Sus scrofa [TaxId:9823]
    Gene: FBP1,FBP
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00636
      • engineered (10)
    Domains in SCOPe 2.07: d2f3ba_
  • Heterogens: F6P, PO4, ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2f3bA (A:)
mtdqaafdtndvtltrfvmeegrkargtgemtqllnslctavkaistavrkagiahlygi
agstnvtgdqvkkldvlsndlvinvlkssfatcvlvseedknaiivepekrgkyvvcfdp
ldgssnidclvsigtifgiyrknstdepsekdalqpgrnlvaagyalygsatmlvlamvn
gvncfmldpaigefilvdrdvkikkkgsiysinegyakefdpaiteyiqrkkfppdnsap
ygaryvgsmvadvhrtlvyggifmypankkspkgklrllyecnpmayvmekagglattgk
eavldivptdihqrapiilgspedvtelleiyqkhaak

    Sequence, based on observed residues (ATOM records): (download) 
    >2f3bA (A:)
dvtltrfvmeegrkargtgemtqllnslctavkaistavrkagiahlygiagstnvtgdq
vkkldvlsndlvinvlkssfatcvlvseedknaiivepekrgkyvvcfdpldgssnidcl
vsigtifgiyrknstdepsekdalqpgrnlvaagyalygsatmlvlamvngvncfmldpa
igefilvdrdvkikkkgsiysinegyakefdpaiteyiqrkkfppdnsapygaryvgsmv
advhrtlvyggifmypankkspkgklrllyecnpmayvmekagglattgkeavldivptd
ihqrapiilgspedvtelleiyqkha