PDB entry 2etm

View 2etm on RCSB PDB site
Description: Crystal Structure of Focal Adhesion Kinase Domain Complexed with 7H-Pyrrolo [2,3-d] pyrimidine Derivative
Class: transferase
Keywords: kinase catalytic domain
Deposited on 2005-10-27, released 2006-10-10
The last revision prior to the SCOP 1.75 freeze date was dated 2006-10-10, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.21
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Focal adhesion kinase 1
    Species: HOMO SAPIENS
    Gene: PTK2, FAK, FAK1
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2etma1
  • Chain 'B':
    Compound: Focal adhesion kinase 1
    Species: HOMO SAPIENS
    Gene: PTK2, FAK, FAK1
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2etmb1
  • Heterogens: 7PY, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2etmA (A:)
gastrdyeiqrerielgrcigegqfgdvhqgiymspenpalavaiktcknctsdsvrekf
lqealtmrqfdhphivkligvitenpvwiimelctlgelrsflqvrkysldlaslilyay
qlstalayleskrfvhrdiaarnvlvssndcvklgdfglsrymedstyykaskgklpikw
mapesinfrrftsasdvwmfgvcmweilmhgvkpfqgvknndvigriengerlpmppncp
ptlyslmtkcwaydpsrrprftelkaqlstileeekaqqee

    Sequence, based on observed residues (ATOM records): (download) 
    >2etmA (A:)
yeiqrerielgrcigegqfgdvhqgiymspenpalavaiktcknctsdsvrekflqealt
mrqfdhphivkligvitenpvwiimelctlgelrsflqvrkysldlaslilyayqlstal
ayleskrfvhrdiaarnvlvssndcvklgdfglsrymeklpikwmapesinfrrftsasd
vwmfgvcmweilmhgvkpfqgvknndvigriengerlpmppncpptlyslmtkcwaydps
rrprftelkaqlstileeekaq

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2etmB (B:)
gastrdyeiqrerielgrcigegqfgdvhqgiymspenpalavaiktcknctsdsvrekf
lqealtmrqfdhphivkligvitenpvwiimelctlgelrsflqvrkysldlaslilyay
qlstalayleskrfvhrdiaarnvlvssndcvklgdfglsrymedstyykaskgklpikw
mapesinfrrftsasdvwmfgvcmweilmhgvkpfqgvknndvigriengerlpmppncp
ptlyslmtkcwaydpsrrprftelkaqlstileeekaqqee

    Sequence, based on observed residues (ATOM records): (download) 
    >2etmB (B:)
rdyeiqrerielgrcigegqfgdvhqgiymspenpalavaiktcknctsdsvrekflqea
ltmrqfdhphivkligvitenpvwiimelctlgelrsflqvrkysldlaslilyayqlst
alayleskrfvhrdiaarnvlvssndcvklgdfglsrlpikwmapesinfrrftsasdvw
mfgvcmweilmhgvkpfqgvknndvigriengerlpmppncpptlyslmtkcwaydpsrr
prftelkaqlstileeekaqqee