PDB entry 2esv

View 2esv on RCSB PDB site
Description: Structure of the HLA-E-VMAPRTLIL/KK50.4 TCR complex
Class: immune system
Keywords: T cell receptor, TCR, HLA-E, CMV, pMHC/TCR complex, IMMUNE SYSTEM
Deposited on 2005-10-27, released 2006-03-21
The last revision prior to the SCOPe 2.04 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.218
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: HLA class I histocompatibility antigen, alpha chain E
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d2esva1, d2esva2
  • Chain 'B':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61769 (1-99)
      • initiating methionine (0)
    Domains in SCOPe 2.04: d2esvb_
  • Chain 'D':
    Compound: KK50.4 T cell receptor alpha chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d2esvd1, d2esvd2
  • Chain 'E':
    Compound: KK50.4 T cell receptor beta chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d2esve1, d2esve2
  • Chain 'P':
    Compound: VMAPRTLIL peptide from CMV gpUL40
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 2ESV (0-8)
  • Heterogens: IOD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2esvA (A:)
    shslkyfhtsvsrpgrgeprfisvgyvddtqfvrfdndaasprmvprapwmeqegseywd
    retrsardtaqifrvnlrtlrgyynqseagshtlqwmhgcelgpdrrflrgyeqfaydgk
    dyltlnedlrswtavdtaaqiseqksndaseaehqrayledtcvewlhkylekgketllh
    leppkthvthhpisdheatlrcwalgfypaeitltwqqdgeghtqdtelvetrpagdgtf
    qkwaavvvpsgeeqrytchvqheglpepvtlrwkp
    

    Sequence, based on observed residues (ATOM records): (download)
    >2esvA (A:)
    shslkyfhtsvsrpgrgeprfisvgyvddtqfvrfdndaasprmvprapwmeqegseywd
    retrsardtaqifrvnlrtlrgyynqseagshtlqwmhgcelgpdrrflrgyeqfaydgk
    dyltlnedlrswtavdtaaqiseqksndaseaehqrayledtcvewlhkylekgketllh
    leppkthvthhpisdheatlrcwalgfypaeitltwqqdtelvetrpagdgtfqkwaavv
    vpsgeeqrytchvqheglpepvtlrwkp
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >2esvB (B:)
    miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
    wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
    

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download)
    >2esvD (D:)
    kttqppsmdcaegraanlpcnhstisgneyvywyrqihsqgpqyiihglknnetnemasl
    iitedrksstlilphatlrdtavyycivvrssntgklifgqgttlqvkpdiqnpdpavyq
    lrdskssdksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavawsnksdf
    acanafnnsiipedtffps
    

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records: (download)
    >2esvE (E:)
    gvtqfpshsviekgqtvtlrcdpisghdnlywyrrvmgkeikfllhfvkeskqdesgmpn
    nrflaertggtystlkvqpaeledsgvyfcassqdrdtqyfgpgtrltvledlknvfppe
    vavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplkeqpaln
    dsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsaeawgrad
    

  • Chain 'P':
    No sequence available.