PDB entry 2esd

View 2esd on RCSB PDB site
Description: Crystal Structure of thioacylenzyme intermediate of an Nadp Dependent Aldehyde Dehydrogenase
Class: oxidoreductase
Keywords: ALDH, GAPN, ternary complex, OXIDOREDUCTASE
Deposited on 2005-10-26, released 2006-05-02
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-10-18, with a file datestamp of 2017-10-13.
Experiment type: XRAY
Resolution: 2.55 Å
R-factor: N/A
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: NADP-dependent glyceraldehyde-3-phosphate dehydrogenase
    Species: Streptococcus mutans [TaxId:1309]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q59931 (Start-474)
      • engineered (249)
    Domains in SCOPe 2.08: d2esda_
  • Chain 'B':
    Compound: NADP-dependent glyceraldehyde-3-phosphate dehydrogenase
    Species: Streptococcus mutans [TaxId:1309]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q59931 (Start-474)
      • engineered (249)
    Domains in SCOPe 2.08: d2esdb_
  • Chain 'C':
    Compound: NADP-dependent glyceraldehyde-3-phosphate dehydrogenase
    Species: Streptococcus mutans [TaxId:1309]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q59931 (Start-474)
      • engineered (249)
    Domains in SCOPe 2.08: d2esdc_
  • Chain 'D':
    Compound: NADP-dependent glyceraldehyde-3-phosphate dehydrogenase
    Species: Streptococcus mutans [TaxId:1309]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q59931 (Start-474)
      • engineered (249)
    Domains in SCOPe 2.08: d2esdd_
  • Heterogens: NAP, G3H, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2esdA (A:)
mtkqyknyvngewklseneikiyepasgaelgsvpamsteevdyvyasakkaqpawrals
yieraaylhkvadilmrdkekigailskevakgyksavsevvrtaeiinyaaeeglrmeg
evleggsfeaaskkkiavvrrepvglvlaispfnypvnlagskiapaliagnviafkppt
qgsisglllaeafaeaglpagvfntitgrgseigdyivehqavnfinftgstgigerigk
magmrpimlalggkdsaivledadleltakniiagafgysgqrctavkrvlvmesvadel
vekirekvlaltignpeddaditplidtksadyveglindandkgatalteikregnlic
pilfdkvttdmrlaweepfgpvlpiirvtsveeaieisnkseyglqasiftndfprafgi
aeqlevgtvhinnktqrgtdnfpflgakksgagiqgvkysieamttvksvvfdik

    Sequence, based on observed residues (ATOM records): (download) 
    >2esdA (A:)
tkqyknyvngewklseneikiyepasgaelgsvpamsteevdyvyasakkaqpawralsy
ieraaylhkvadilmrdkekigailskevakgyksavsevvrtaeiinyaaeeglrmege
vleggsfeaaskkkiavvrrepvglvlaispfnypvnlagskiapaliagnviafkpptq
gsisglllaeafaeaglpagvfntitgrgseigdyivehqavnfinftgstgigerigkm
agmrpimlalggkdsaivledadleltakniiagafgysgqrctavkrvlvmesvadelv
ekirekvlaltignpeddaditplidtksadyveglindandkgatalteikregnlicp
ilfdkvttdmrlaweepfgpvlpiirvtsveeaieisnkseyglqasiftndfprafgia
eqlevgtvhinnktqrgtdnfpflgakksgagiqgvkysieamttvksvvfdik

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2esdB (B:)
mtkqyknyvngewklseneikiyepasgaelgsvpamsteevdyvyasakkaqpawrals
yieraaylhkvadilmrdkekigailskevakgyksavsevvrtaeiinyaaeeglrmeg
evleggsfeaaskkkiavvrrepvglvlaispfnypvnlagskiapaliagnviafkppt
qgsisglllaeafaeaglpagvfntitgrgseigdyivehqavnfinftgstgigerigk
magmrpimlalggkdsaivledadleltakniiagafgysgqrctavkrvlvmesvadel
vekirekvlaltignpeddaditplidtksadyveglindandkgatalteikregnlic
pilfdkvttdmrlaweepfgpvlpiirvtsveeaieisnkseyglqasiftndfprafgi
aeqlevgtvhinnktqrgtdnfpflgakksgagiqgvkysieamttvksvvfdik

    Sequence, based on observed residues (ATOM records): (download) 
    >2esdB (B:)
tkqyknyvngewklseneikiyepasgaelgsvpamsteevdyvyasakkaqpawralsy
ieraaylhkvadilmrdkekigailskevakgyksavsevvrtaeiinyaaeeglrmege
vleggsfeaaskkkiavvrrepvglvlaispfnypvnlagskiapaliagnviafkpptq
gsisglllaeafaeaglpagvfntitgrgseigdyivehqavnfinftgstgigerigkm
agmrpimlalggkdsaivledadleltakniiagafgysgqrctavkrvlvmesvadelv
ekirekvlaltignpeddaditplidtksadyveglindandkgatalteikregnlicp
ilfdkvttdmrlaweepfgpvlpiirvtsveeaieisnkseyglqasiftndfprafgia
eqlevgtvhinnktqrgtdnfpflgakksgagiqgvkysieamttvksvvfdik

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2esdC (C:)
mtkqyknyvngewklseneikiyepasgaelgsvpamsteevdyvyasakkaqpawrals
yieraaylhkvadilmrdkekigailskevakgyksavsevvrtaeiinyaaeeglrmeg
evleggsfeaaskkkiavvrrepvglvlaispfnypvnlagskiapaliagnviafkppt
qgsisglllaeafaeaglpagvfntitgrgseigdyivehqavnfinftgstgigerigk
magmrpimlalggkdsaivledadleltakniiagafgysgqrctavkrvlvmesvadel
vekirekvlaltignpeddaditplidtksadyveglindandkgatalteikregnlic
pilfdkvttdmrlaweepfgpvlpiirvtsveeaieisnkseyglqasiftndfprafgi
aeqlevgtvhinnktqrgtdnfpflgakksgagiqgvkysieamttvksvvfdik

    Sequence, based on observed residues (ATOM records): (download) 
    >2esdC (C:)
tkqyknyvngewklseneikiyepasgaelgsvpamsteevdyvyasakkaqpawralsy
ieraaylhkvadilmrdkekigailskevakgyksavsevvrtaeiinyaaeeglrmege
vleggsfeaaskkkiavvrrepvglvlaispfnypvnlagskiapaliagnviafkpptq
gsisglllaeafaeaglpagvfntitgrgseigdyivehqavnfinftgstgigerigkm
agmrpimlalggkdsaivledadleltakniiagafgysgqrctavkrvlvmesvadelv
ekirekvlaltignpeddaditplidtksadyveglindandkgatalteikregnlicp
ilfdkvttdmrlaweepfgpvlpiirvtsveeaieisnkseyglqasiftndfprafgia
eqlevgtvhinnktqrgtdnfpflgakksgagiqgvkysieamttvksvvfdik

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2esdD (D:)
mtkqyknyvngewklseneikiyepasgaelgsvpamsteevdyvyasakkaqpawrals
yieraaylhkvadilmrdkekigailskevakgyksavsevvrtaeiinyaaeeglrmeg
evleggsfeaaskkkiavvrrepvglvlaispfnypvnlagskiapaliagnviafkppt
qgsisglllaeafaeaglpagvfntitgrgseigdyivehqavnfinftgstgigerigk
magmrpimlalggkdsaivledadleltakniiagafgysgqrctavkrvlvmesvadel
vekirekvlaltignpeddaditplidtksadyveglindandkgatalteikregnlic
pilfdkvttdmrlaweepfgpvlpiirvtsveeaieisnkseyglqasiftndfprafgi
aeqlevgtvhinnktqrgtdnfpflgakksgagiqgvkysieamttvksvvfdik

    Sequence, based on observed residues (ATOM records): (download) 
    >2esdD (D:)
tkqyknyvngewklseneikiyepasgaelgsvpamsteevdyvyasakkaqpawralsy
ieraaylhkvadilmrdkekigailskevakgyksavsevvrtaeiinyaaeeglrmege
vleggsfeaaskkkiavvrrepvglvlaispfnypvnlagskiapaliagnviafkpptq
gsisglllaeafaeaglpagvfntitgrgseigdyivehqavnfinftgstgigerigkm
agmrpimlalggkdsaivledadleltakniiagafgysgqrctavkrvlvmesvadelv
ekirekvlaltignpeddaditplidtksadyveglindandkgatalteikregnlicp
ilfdkvttdmrlaweepfgpvlpiirvtsveeaieisnkseyglqasiftndfprafgia
eqlevgtvhinnktqrgtdnfpflgakksgagiqgvkysieamttvksvvfdik