PDB entry 2eik

View 2eik on RCSB PDB site
Description: Cadmium ion binding structure of bovine heart cytochrome C oxidase in the fully reduced state
Class: oxidoreductase
Keywords: oxidoreductase
Deposited on 2007-03-13, released 2007-05-29
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.199
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cytochrome c oxidase subunit 1
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2eika_
  • Chain 'B':
    Compound: Cytochrome c oxidase subunit 2
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2eikb1, d2eikb2
  • Chain 'C':
    Compound: Cytochrome c oxidase subunit 3
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2eikc_
  • Chain 'D':
    Compound: Cytochrome c oxidase subunit 4 isoform 1
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2eikd_
  • Chain 'E':
    Compound: Cytochrome c oxidase polypeptide Va
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2eike_
  • Chain 'F':
    Compound: Cytochrome c oxidase polypeptide Vb
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2eikf_
  • Chain 'G':
    Compound: Cytochrome c oxidase polypeptide VIa-heart
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2eikg_
  • Chain 'H':
    Compound: Cytochrome c oxidase subunit VIb isoform 1
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2eikh_
  • Chain 'I':
    Compound: Cytochrome c oxidase polypeptide VIc
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2eiki_
  • Chain 'J':
    Compound: Cytochrome c oxidase polypeptide VIIa-heart
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2eikj_
  • Chain 'K':
    Compound: Cytochrome c oxidase polypeptide VIIb
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2eikk_
  • Chain 'L':
    Compound: Cytochrome c oxidase polypeptide VIIc
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2eikl_
  • Chain 'M':
    Compound: Cytochrome c oxidase polypeptide VIII-heart
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2eikm_
  • Chain 'N':
    Compound: Cytochrome c oxidase subunit 1
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2eikn_
  • Chain 'O':
    Compound: Cytochrome c oxidase subunit 2
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2eiko1, d2eiko2
  • Chain 'P':
    Compound: Cytochrome c oxidase subunit 3
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2eikp_
  • Chain 'Q':
    Compound: Cytochrome c oxidase subunit 4 isoform 1
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2eikq_
  • Chain 'R':
    Compound: Cytochrome c oxidase polypeptide Va
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2eikr_
  • Chain 'S':
    Compound: Cytochrome c oxidase polypeptide Vb
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2eiks_
  • Chain 'T':
    Compound: Cytochrome c oxidase polypeptide VIa-heart
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2eikt_
  • Chain 'U':
    Compound: Cytochrome c oxidase subunit VIb isoform 1
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2eiku_
  • Chain 'V':
    Compound: Cytochrome c oxidase polypeptide VIc
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2eikv_
  • Chain 'W':
    Compound: Cytochrome c oxidase polypeptide VIIa-heart
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2eikw_
  • Chain 'X':
    Compound: Cytochrome c oxidase polypeptide VIIb
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2eikx_
  • Chain 'Y':
    Compound: Cytochrome c oxidase polypeptide VIIc
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2eiky_
  • Chain 'Z':
    Compound: Cytochrome c oxidase polypeptide VIII-heart
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2eikz_
  • Heterogens: CU, MG, NA, CD, HEA, TGL, PGV, CUA, PSC, CHD, DMU, PEK, CDL, ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2eikA (A:)
mfinrwlfstnhkdigtlyllfgawagmvgtalslliraelgqpgtllgddqiynvvvta
hafvmiffmvmpimiggfgnwlvplmigapdmafprmnnmsfwllppsfllllassmvea
gagtgwtvypplagnlahagasvdltifslhlagvssilgainfittiinmkppamsqyq
tplfvwsvmitavllllslpvlaagitmlltdrnlnttffdpagggdpilyqhlfwffgh
pevyililpgfgmishivtyysgkkepfgymgmvwammsigflgfivwahhmftvgmdvd
trayftsatmiiaiptgvkvfswlatlhggnikwspammwalgfiflftvggltgivlan
ssldivlhdtyyvvahfhyvlsmgavfaimggfvhwfplfsgytlndtwakihfaimfvg
vnmtffpqhflglsgmprrysdypdaytmwntissmgsfisltavmlmvfiiweafaskr
evltvdltttnlewlngcpppyhtfeeptyvnlk

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2eikB (B:)
maypmqlgfqdatspimeellhfhdhtlmivflisslvlyiislmlttklthtstmdaqe
vetiwtilpaiililialpslrilymmdeinnpsltvktmghqwywsyeytdyedlsfds
ymiptselkpgelrllevdnrvvlpmemtirmlvssedvlhswavpslglktdaipgrln
qttlmssrpglyygqcseicgsnhsfmpivlelvplkyfekwsasml

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2eikC (C:)
mthqthayhmvnpspwpltgalsallmtsgltmwfhfnsmtllmiglttnmltmyqwwrd
virestfqghhtpavqkglrygmilfiisevlfftgffwafyhsslaptpelggcwpptg
ihplnplevpllntsvllasgvsitwahhslmegdrkhmlqalfititlgvyftllqase
yyeapftisdgvygstffvatgfhglhviigstflivcffrqlkfhftsnhhfgfeaaaw
ywhfvdvvwlflyvsiywwgs

    Sequence, based on observed residues (ATOM records): (download) 
    >2eikC (C:)
hqthayhmvnpspwpltgalsallmtsgltmwfhfnsmtllmiglttnmltmyqwwrdvi
restfqghhtpavqkglrygmilfiisevlfftgffwafyhsslaptpelggcwpptgih
plnplevpllntsvllasgvsitwahhslmegdrkhmlqalfititlgvyftllqaseyy
eapftisdgvygstffvatgfhglhviigstflivcffrqlkfhftsnhhfgfeaaawyw
hfvdvvwlflyvsiywwgs

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2eikD (D:)
ahgsvvksedyalpsyvdrrdyplpdvahvknlsasqkalkekekaswsslsidekvely
rlkfkesfaemnrstnewktvvgaamffigftallliwekhyvygpiphtfeeewvakqt
krmldmkvapiqgfsakwdydknewkk

    Sequence, based on observed residues (ATOM records): (download) 
    >2eikD (D:)
svvksedyalpsyvdrrdyplpdvahvknlsasqkalkekekaswsslsidekvelyrlk
fkesfaemnrstnewktvvgaamffigftallliwekhyvygpiphtfeeewvakqtkrm
ldmkvapiqgfsakwdydknewkk

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >2eikE (E:)
shgshetdeefdarwvtyfnkpdidawelrkgmntlvgydlvpepkiidaalracrrlnd
fasavrilevvkdkagphkeiypyviqelrptlnelgistpeelgldkv

    Sequence, based on observed residues (ATOM records): (download) 
    >2eikE (E:)
hetdeefdarwvtyfnkpdidawelrkgmntlvgydlvpepkiidaalracrrlndfasa
vrilevvkdkagphkeiypyviqelrptlnelgistpeelgldkv

  • Chain 'F':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2eikF (F:)
asgggvptdeeqatglerevmlaarkgqdpynilapkatsgtkedpnlvpsitnkrivgc
iceednstviwfwlhkgeaqrcpscgthyklvphqlah

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >2eikG (G:)
asaakgdhggtgartwrfltfglalpsvalctlnswlhsghrerpafipyhhlrirtkpf
swgdgnhtffhnprvnplptgyekp

    Sequence, based on observed residues (ATOM records): (download) 
    >2eikG (G:)
asaakgdhggtgartwrfltfglalpsvalctlnswlhsghrerpafipyhhlrirtkpf
swgdgnhtffhnprvnplptgyek

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >2eikH (H:)
aediqakiknyqtapfdsrfpnqnqtrncwqnyldfhrcekamtakggdvsvcewyrrvy
kslcpiswvstwddrraegtfpgki

    Sequence, based on observed residues (ATOM records): (download) 
    >2eikH (H:)
kiknyqtapfdsrfpnqnqtrncwqnyldfhrcekamtakggdvsvcewyrrvykslcpi
swvstwddrraegtfpgki

  • Chain 'I':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2eikI (I:)
stalakpqmrgllarrlrfhivgafmvslgfatfykfavaekrkkayadfyrnydsmkdf
eemrkagifqsak

  • Chain 'J':
    Sequence, based on SEQRES records: (download) 
    >2eikJ (J:)
fenrvaekqklfqednglpvhlkggatdnilyrvtmtlclggtlyslyclgwasfphkk

    Sequence, based on observed residues (ATOM records): (download) 
    >2eikJ (J:)
fenrvaekqklfqednglpvhlkggatdnilyrvtmtlclggtlyslyclgwasfphk

  • Chain 'K':
    Sequence, based on SEQRES records: (download) 
    >2eikK (K:)
ihqkrapdfhdkygnavlasgatfcvavwvymatqigiewnpspvgrvtpkewreq

    Sequence, based on observed residues (ATOM records): (download) 
    >2eikK (K:)
apdfhdkygnavlasgatfcvavwvymatqigiewnpspvgrvtpkewr

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >2eikL (L:)
shyeegpgknipfsvenkwrllammtlffgsgfaapffivrhqllkk

    Sequence, based on observed residues (ATOM records): (download) 
    >2eikL (L:)
hyeegpgknipfsvenkwrllammtlffgsgfaapffivrhqllkk

  • Chain 'M':
    Sequence, based on SEQRES records: (download) 
    >2eikM (M:)
itakpaktptspkeqaiglsvtflsfllpagwvlyhldnykkssaa

    Sequence, based on observed residues (ATOM records): (download) 
    >2eikM (M:)
itakpaktptspkeqaiglsvtflsfllpagwvlyhldnykks

  • Chain 'N':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2eikN (N:)
mfinrwlfstnhkdigtlyllfgawagmvgtalslliraelgqpgtllgddqiynvvvta
hafvmiffmvmpimiggfgnwlvplmigapdmafprmnnmsfwllppsfllllassmvea
gagtgwtvypplagnlahagasvdltifslhlagvssilgainfittiinmkppamsqyq
tplfvwsvmitavllllslpvlaagitmlltdrnlnttffdpagggdpilyqhlfwffgh
pevyililpgfgmishivtyysgkkepfgymgmvwammsigflgfivwahhmftvgmdvd
trayftsatmiiaiptgvkvfswlatlhggnikwspammwalgfiflftvggltgivlan
ssldivlhdtyyvvahfhyvlsmgavfaimggfvhwfplfsgytlndtwakihfaimfvg
vnmtffpqhflglsgmprrysdypdaytmwntissmgsfisltavmlmvfiiweafaskr
evltvdltttnlewlngcpppyhtfeeptyvnlk

  • Chain 'O':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2eikO (O:)
maypmqlgfqdatspimeellhfhdhtlmivflisslvlyiislmlttklthtstmdaqe
vetiwtilpaiililialpslrilymmdeinnpsltvktmghqwywsyeytdyedlsfds
ymiptselkpgelrllevdnrvvlpmemtirmlvssedvlhswavpslglktdaipgrln
qttlmssrpglyygqcseicgsnhsfmpivlelvplkyfekwsasml

  • Chain 'P':
    Sequence, based on SEQRES records: (download) 
    >2eikP (P:)
mthqthayhmvnpspwpltgalsallmtsgltmwfhfnsmtllmiglttnmltmyqwwrd
virestfqghhtpavqkglrygmilfiisevlfftgffwafyhsslaptpelggcwpptg
ihplnplevpllntsvllasgvsitwahhslmegdrkhmlqalfititlgvyftllqase
yyeapftisdgvygstffvatgfhglhviigstflivcffrqlkfhftsnhhfgfeaaaw
ywhfvdvvwlflyvsiywwgs

    Sequence, based on observed residues (ATOM records): (download) 
    >2eikP (P:)
hqthayhmvnpspwpltgalsallmtsgltmwfhfnsmtllmiglttnmltmyqwwrdvi
restfqghhtpavqkglrygmilfiisevlfftgffwafyhsslaptpelggcwpptgih
plnplevpllntsvllasgvsitwahhslmegdrkhmlqalfititlgvyftllqaseyy
eapftisdgvygstffvatgfhglhviigstflivcffrqlkfhftsnhhfgfeaaawyw
hfvdvvwlflyvsiywwgs

  • Chain 'Q':
    Sequence, based on SEQRES records: (download) 
    >2eikQ (Q:)
ahgsvvksedyalpsyvdrrdyplpdvahvknlsasqkalkekekaswsslsidekvely
rlkfkesfaemnrstnewktvvgaamffigftallliwekhyvygpiphtfeeewvakqt
krmldmkvapiqgfsakwdydknewkk

    Sequence, based on observed residues (ATOM records): (download) 
    >2eikQ (Q:)
svvksedyalpsyvdrrdyplpdvahvknlsasqkalkekekaswsslsidekvelyrlk
fkesfaemnrstnewktvvgaamffigftallliwekhyvygpiphtfeeewvakqtkrm
ldmkvapiqgfsakwdydknewkk

  • Chain 'R':
    Sequence, based on SEQRES records: (download) 
    >2eikR (R:)
shgshetdeefdarwvtyfnkpdidawelrkgmntlvgydlvpepkiidaalracrrlnd
fasavrilevvkdkagphkeiypyviqelrptlnelgistpeelgldkv

    Sequence, based on observed residues (ATOM records): (download) 
    >2eikR (R:)
hetdeefdarwvtyfnkpdidawelrkgmntlvgydlvpepkiidaalracrrlndfasa
vrilevvkdkagphkeiypyviqelrptlnelgistpeelgldkv

  • Chain 'S':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2eikS (S:)
asgggvptdeeqatglerevmlaarkgqdpynilapkatsgtkedpnlvpsitnkrivgc
iceednstviwfwlhkgeaqrcpscgthyklvphqlah

  • Chain 'T':
    Sequence, based on SEQRES records: (download) 
    >2eikT (T:)
asaakgdhggtgartwrfltfglalpsvalctlnswlhsghrerpafipyhhlrirtkpf
swgdgnhtffhnprvnplptgyekp

    Sequence, based on observed residues (ATOM records): (download) 
    >2eikT (T:)
asaakgdhggtgartwrfltfglalpsvalctlnswlhsghrerpafipyhhlrirtkpf
swgdgnhtffhnprvnplptgyek

  • Chain 'U':
    Sequence, based on SEQRES records: (download) 
    >2eikU (U:)
aediqakiknyqtapfdsrfpnqnqtrncwqnyldfhrcekamtakggdvsvcewyrrvy
kslcpiswvstwddrraegtfpgki

    Sequence, based on observed residues (ATOM records): (download) 
    >2eikU (U:)
kiknyqtapfdsrfpnqnqtrncwqnyldfhrcekamtakggdvsvcewyrrvykslcpi
swvstwddrraegtfpgki

  • Chain 'V':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2eikV (V:)
stalakpqmrgllarrlrfhivgafmvslgfatfykfavaekrkkayadfyrnydsmkdf
eemrkagifqsak

  • Chain 'W':
    Sequence, based on SEQRES records: (download) 
    >2eikW (W:)
fenrvaekqklfqednglpvhlkggatdnilyrvtmtlclggtlyslyclgwasfphkk

    Sequence, based on observed residues (ATOM records): (download) 
    >2eikW (W:)
fenrvaekqklfqednglpvhlkggatdnilyrvtmtlclggtlyslyclgwasfphk

  • Chain 'X':
    Sequence, based on SEQRES records: (download) 
    >2eikX (X:)
ihqkrapdfhdkygnavlasgatfcvavwvymatqigiewnpspvgrvtpkewreq

    Sequence, based on observed residues (ATOM records): (download) 
    >2eikX (X:)
apdfhdkygnavlasgatfcvavwvymatqigiewnpspvgrvtpkewr

  • Chain 'Y':
    Sequence, based on SEQRES records: (download) 
    >2eikY (Y:)
shyeegpgknipfsvenkwrllammtlffgsgfaapffivrhqllkk

    Sequence, based on observed residues (ATOM records): (download) 
    >2eikY (Y:)
hyeegpgknipfsvenkwrllammtlffgsgfaapffivrhqllkk

  • Chain 'Z':
    Sequence, based on SEQRES records: (download) 
    >2eikZ (Z:)
itakpaktptspkeqaiglsvtflsfllpagwvlyhldnykkssaa

    Sequence, based on observed residues (ATOM records): (download) 
    >2eikZ (Z:)
itakpaktptspkeqaiglsvtflsfllpagwvlyhldnykks